| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the gelsemine-2162 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AGTPBP1 | ATP/GTP binding protein 1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ATP10A | ATPase, class V, type 10A |
| AURKA | aurora kinase A |
| B9D2 | B9 protein domain 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTNL3 | butyrophilin-like 3 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CASZ1 | castor zinc finger 1 |
| CEP68 | centrosomal protein 68kDa |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRP | C-reactive protein, pentraxin-related |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DND1 | DND microRNA-mediated repression inhibitor 1 |
| EFHD1 | EF-hand domain family, member D1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPHB2 | EPH receptor B2 |
| FAM127B | family with sequence similarity 127, member B |
| FAM65A | family with sequence similarity 65, member A |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGF9 | fibroblast growth factor 9 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXG1 | forkhead box G1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GALC | galactosylceramidase |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GK | glycerol kinase |
| GPR135 | G protein-coupled receptor 135 |
| GPR20 | G protein-coupled receptor 20 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H1B | histone cluster 1, H1b |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HPX | hemopexin |
| IFT74 | intraflagellar transport 74 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0040 | KIAA0040 |
| KIAA1456 | KIAA1456 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MMP25 | matrix metallopeptidase 25 |
| MTAP | methylthioadenosine phosphorylase |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NARFL | nuclear prelamin A recognition factor-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEK11 | NIMA-related kinase 11 |
| NIPAL2 | NIPA-like domain containing 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PTEN | phosphatase and tensin homolog |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| REC8 | REC8 meiotic recombination protein |
| RGS19 | regulator of G-protein signaling 19 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH3BP1 | SH3-domain binding protein 1 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SIL1 | SIL1 nucleotide exchange factor |
| SIN3B | SIN3 transcription regulator family member B |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMC1A | structural maintenance of chromosomes 1A |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STOM | stomatin |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UBOX5 | U-box domain containing 5 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WDR25 | WD repeat domain 25 |
| WRAP53 | WD repeat containing, antisense to TP53 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| APOBR | apolipoprotein B receptor |
| ARG1 | arginase 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AVPI1 | arginine vasopressin-induced 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C5 | complement component 5 |
| CA11 | carbonic anhydrase XI |
| CCDC186 | coiled-coil domain containing 186 |
| CNTN1 | contactin 1 |
| CORO7 | coronin 7 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DOK5 | docking protein 5 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBRS | fibrosin |
| FNBP1L | formin binding protein 1-like |
| GAMT | guanidinoacetate N-methyltransferase |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR19 | G protein-coupled receptor 19 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H4D | histone cluster 1, H4d |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HYAL3 | hyaluronoglucosaminidase 3 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| ITGA10 | integrin, alpha 10 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAK | male germ cell-associated kinase |
| MAPK3 | mitogen-activated protein kinase 3 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MED15 | mediator complex subunit 15 |
| MKS1 | Meckel syndrome, type 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYOZ3 | myozenin 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| POMZP3 | POM121 and ZP3 fusion |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAMEF11 | PRAME family member 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PROCR | protein C receptor, endothelial |
| PRSS53 | protease, serine, 53 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RETN | resistin |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF122 | ring finger protein 122 |
| RNF39 | ring finger protein 39 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STX17 | syntaxin 17 |
| TCTN1 | tectonic family member 1 |
| TEC | tec protein tyrosine kinase |
| TMEM120B | transmembrane protein 120B |
| TMEM212 | transmembrane protein 212 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| USP19 | ubiquitin specific peptidase 19 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR91 | WD repeat domain 91 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF197 | zinc finger protein 197 |
| ZNF225 | zinc finger protein 225 |
| ZNF345 | zinc finger protein 345 |
| ZNF528 | zinc finger protein 528 |
| ZNF749 | zinc finger protein 749 |
| ZNF93 | zinc finger protein 93 |
