gelsemine-2817 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the gelsemine-2817 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP7 A kinase (PRKA) anchor protein 7
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALS2CL ALS2 C-terminal like
APOE apolipoprotein E
ARHGAP33 Rho GTPase activating protein 33
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP10B ATPase, class V, type 10B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF66 chromosome 19 open reading frame 66
C2 complement component 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK1D calcium/calmodulin-dependent protein kinase ID
CD82 CD82 molecule
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CLCN7 chloride channel, voltage-sensitive 7
CLTA clathrin, light chain A
CRIP1 cysteine-rich protein 1 (intestinal)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ELOVL5 ELOVL fatty acid elongase 5
EMC1 ER membrane protein complex subunit 1
FAM120C family with sequence similarity 120C
FGF5 fibroblast growth factor 5
FH fumarate hydratase
FRY furry homolog (Drosophila)
GGT1 gamma-glutamyltransferase 1
HPS1 Hermansky-Pudlak syndrome 1
HSF1 heat shock transcription factor 1
IL22 interleukin 22
IQCC IQ motif containing C
ITGB6 integrin, beta 6
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNIP1 Kv channel interacting protein 1
KRT6B keratin 6B, type II
LEPR leptin receptor
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP2 mannan-binding lectin serine peptidase 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MST1L macrophage stimulating 1-like
MYH14 myosin, heavy chain 14, non-muscle
MYOF myoferlin
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NXPH4 neurexophilin 4
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAX2 paired box 2
PCDHB3 protocadherin beta 3
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4DIP phosphodiesterase 4D interacting protein
PHF8 PHD finger protein 8
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
PRF1 perforin 1 (pore forming protein)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB3B RAB3B, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RETN resistin
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL37A ribosomal protein L37a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNX1 runt-related transcription factor 1
SCN1B sodium channel, voltage gated, type I beta subunit
SH3BP2 SH3-domain binding protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNX29P2 sorting nexin 29 pseudogene 2
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPDEF SAM pointed domain containing ETS transcription factor
SPHK2 sphingosine kinase 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR2B small proline-rich protein 2B
SYNDIG1 synapse differentiation inducing 1
TAPBP TAP binding protein (tapasin)
TFDP3 transcription factor Dp family, member 3
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TRIL TLR4 interactor with leucine-rich repeats
TUBA4B tubulin, alpha 4b
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VILL villin-like
VIM vimentin
WNT2B wingless-type MMTV integration site family, member 2B
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ARHGAP17 Rho GTPase activating protein 17
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARRB1 arrestin, beta 1
BCORL1 BCL6 corepressor-like 1
C21ORF91 chromosome 21 open reading frame 91
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNO cyclin O
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CLCN6 chloride channel, voltage-sensitive 6
COL4A5 collagen, type IV, alpha 5
CPTP ceramide-1-phosphate transfer protein
CSTA cystatin A (stefin A)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EVPL envoplakin
F3 coagulation factor III (thromboplastin, tissue factor)
FCHO1 FCH domain only 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FSD1 fibronectin type III and SPRY domain containing 1
GCHFR GTP cyclohydrolase I feedback regulator
GFI1 growth factor independent 1 transcription repressor
GNL1 guanine nucleotide binding protein-like 1
HIST1H2AL histone cluster 1, H2al
IQCG IQ motif containing G
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIAA0355 KIAA0355
KIAA0513 KIAA0513
KLHL26 kelch-like family member 26
LRRC8E leucine rich repeat containing 8 family, member E
LYPD1 LY6/PLAUR domain containing 1
MATK megakaryocyte-associated tyrosine kinase
METTL16 methyltransferase like 16
METTL2B methyltransferase like 2B
MFAP2 microfibrillar-associated protein 2
MKNK2 MAP kinase interacting serine/threonine kinase 2
MNX1 motor neuron and pancreas homeobox 1
MON1B MON1 secretory trafficking family member B
MRPS18C mitochondrial ribosomal protein S18C
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PARP12 poly (ADP-ribose) polymerase family, member 12
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC8 placenta-specific 8
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRSS8 protease, serine, 8
QTRT1 queuine tRNA-ribosyltransferase 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHOBTB2 Rho-related BTB domain containing 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF31 ring finger protein 31
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
SAYSD1 SAYSVFN motif domain containing 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIRT6 sirtuin 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SPHK1 sphingosine kinase 1
SPINK4 serine peptidase inhibitor, Kazal type 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STRN striatin, calmodulin binding protein
TAOK1 TAO kinase 1
TESC tescalcin
TESK2 testis-specific kinase 2
TFPI2 tissue factor pathway inhibitor 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRABD TraB domain containing
TRIM21 tripartite motif containing 21
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VWA1 von Willebrand factor A domain containing 1
WDR25 WD repeat domain 25
WDR91 WD repeat domain 91
ZBED1 zinc finger, BED-type containing 1
ZNF16 zinc finger protein 16
ZNF219 zinc finger protein 219
ZNF282 zinc finger protein 282
ZNF668 zinc finger protein 668
ZSCAN26 zinc finger and SCAN domain containing 26