| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the gelsemine-2817 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALS2CL | ALS2 C-terminal like |
| APOE | apolipoprotein E |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP10B | ATPase, class V, type 10B |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C2 | complement component 2 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CD82 | CD82 molecule |
| CES3 | carboxylesterase 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLTA | clathrin, light chain A |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EMC1 | ER membrane protein complex subunit 1 |
| FAM120C | family with sequence similarity 120C |
| FGF5 | fibroblast growth factor 5 |
| FH | fumarate hydratase |
| FRY | furry homolog (Drosophila) |
| GGT1 | gamma-glutamyltransferase 1 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HSF1 | heat shock transcription factor 1 |
| IL22 | interleukin 22 |
| IQCC | IQ motif containing C |
| ITGB6 | integrin, beta 6 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KRT6B | keratin 6B, type II |
| LEPR | leptin receptor |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MST1L | macrophage stimulating 1-like |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYOF | myoferlin |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NXPH4 | neurexophilin 4 |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAX2 | paired box 2 |
| PCDHB3 | protocadherin beta 3 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHF8 | PHD finger protein 8 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| RAB3B | RAB3B, member RAS oncogene family |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RETN | resistin |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL37A | ribosomal protein L37a |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RUNX1 | runt-related transcription factor 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPHK2 | sphingosine kinase 2 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRR2B | small proline-rich protein 2B |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAPBP | TAP binding protein (tapasin) |
| TFDP3 | transcription factor Dp family, member 3 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TUBA4B | tubulin, alpha 4b |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VILL | villin-like |
| VIM | vimentin |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARRB1 | arrestin, beta 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCNO | cyclin O |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL4A5 | collagen, type IV, alpha 5 |
| CPTP | ceramide-1-phosphate transfer protein |
| CSTA | cystatin A (stefin A) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EVPL | envoplakin |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FCHO1 | FCH domain only 1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GFI1 | growth factor independent 1 transcription repressor |
| GNL1 | guanine nucleotide binding protein-like 1 |
| HIST1H2AL | histone cluster 1, H2al |
| IQCG | IQ motif containing G |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KIAA0355 | KIAA0355 |
| KIAA0513 | KIAA0513 |
| KLHL26 | kelch-like family member 26 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| METTL16 | methyltransferase like 16 |
| METTL2B | methyltransferase like 2B |
| MFAP2 | microfibrillar-associated protein 2 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MON1B | MON1 secretory trafficking family member B |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLAC8 | placenta-specific 8 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRSS8 | protease, serine, 8 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF31 | ring finger protein 31 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SIRT6 | sirtuin 6 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SPHK1 | sphingosine kinase 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STRN | striatin, calmodulin binding protein |
| TAOK1 | TAO kinase 1 |
| TESC | tescalcin |
| TESK2 | testis-specific kinase 2 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRABD | TraB domain containing |
| TRIM21 | tripartite motif containing 21 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBA3C | tubulin, alpha 3c |
| TWF2 | twinfilin actin binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR25 | WD repeat domain 25 |
| WDR91 | WD repeat domain 91 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF219 | zinc finger protein 219 |
| ZNF282 | zinc finger protein 282 |
| ZNF668 | zinc finger protein 668 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |