gelsemine-4097 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the gelsemine-4097 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ADAM20 ADAM metallopeptidase domain 20
ADCK2 aarF domain containing kinase 2
AFF1 AF4/FMR2 family, member 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALOX5 arachidonate 5-lipoxygenase
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APP amyloid beta (A4) precursor protein
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B9D2 B9 protein domain 2
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BST1 bone marrow stromal cell antigen 1
C21ORF2 chromosome 21 open reading frame 2
C2CD2L C2CD2-like
CADM1 cell adhesion molecule 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMP cathelicidin antimicrobial peptide
CCDC134 coiled-coil domain containing 134
CCDC177 coiled-coil domain containing 177
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLTA clathrin, light chain A
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DIO2 deiodinase, iodothyronine, type II
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DTNA dystrobrevin, alpha
EPHA1 EPH receptor A1
EPX eosinophil peroxidase
EPYC epiphycan
FAM105A family with sequence similarity 105, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FILIP1L filamin A interacting protein 1-like
FLJ42627 uncharacterized LOC645644
FRMD4B FERM domain containing 4B
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GSPT1 G1 to S phase transition 1
HBB hemoglobin, beta
HNF4A hepatocyte nuclear factor 4, alpha
HOXD1 homeobox D1
IFNA16 interferon, alpha 16
IGF1 insulin-like growth factor 1 (somatomedin C)
IHH indian hedgehog
ITM2A integral membrane protein 2A
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA0485 uncharacterized LOC57235
KIF25 kinesin family member 25
KLF12 Kruppel-like factor 12
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MST1 macrophage stimulating 1
MTMR3 myotubularin related protein 3
NFASC neurofascin
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
ONECUT2 one cut homeobox 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALMD palmdelphin
PAPPA2 pappalysin 2
PCDH1 protocadherin 1
PHF3 PHD finger protein 3
PIP prolactin-induced protein
PKP4 plakophilin 4
PLAG1 pleiomorphic adenoma gene 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PRB3 proline-rich protein BstNI subfamily 3
PRSS21 protease, serine, 21 (testisin)
PTCRA pre T-cell antigen receptor alpha
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBBP9 retinoblastoma binding protein 9
RNF122 ring finger protein 122
RRH retinal pigment epithelium-derived rhodopsin homolog
SARM1 sterile alpha and TIR motif containing 1
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIGLEC6 sialic acid binding Ig-like lectin 6
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SOX5 SRY (sex determining region Y)-box 5
SRSF7 serine/arginine-rich splicing factor 7
STXBP5L syntaxin binding protein 5-like
SUGP1 SURP and G patch domain containing 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUSD5 sushi domain containing 5
SYCP2 synaptonemal complex protein 2
TBX1 T-box 1
TFEB transcription factor EB
TNIK TRAF2 and NCK interacting kinase
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSC22D2 TSC22 domain family, member 2
TSPAN9 tetraspanin 9
TSPY1 testis specific protein, Y-linked 1
ZNF235 zinc finger protein 235
ZNF277 zinc finger protein 277
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AK5 adenylate kinase 5
AKAP5 A kinase (PRKA) anchor protein 5
AMH anti-Mullerian hormone
ANXA2P3 annexin A2 pseudogene 3
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARHGAP22 Rho GTPase activating protein 22
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B3GAT1 beta-1,3-glucuronyltransferase 1
BMP10 bone morphogenetic protein 10
BRSK2 BR serine/threonine kinase 2
CCL21 chemokine (C-C motif) ligand 21
CCL27 chemokine (C-C motif) ligand 27
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
ECM1 extracellular matrix protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBRS fibrosin
FBXO22 F-box protein 22
FBXO31 F-box protein 31
FGF6 fibroblast growth factor 6
FRMPD1 FERM and PDZ domain containing 1
GAB1 GRB2-associated binding protein 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H1D histone cluster 1, H1d
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA4 homeobox A4
HOXA6 homeobox A6
IL12A interleukin 12A
IL36RN interleukin 36 receptor antagonist
IRAK4 interleukin-1 receptor-associated kinase 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KLF1 Kruppel-like factor 1 (erythroid)
KLHL25 kelch-like family member 25
KRT31 keratin 31, type I
KRT8P12 keratin 8 pseudogene 12
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC2 leucine rich repeat containing 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYPD3 LY6/PLAUR domain containing 3
MAGEC3 melanoma antigen family C3
MGC2889 uncharacterized protein MGC2889
MGP matrix Gla protein
MMRN2 multimerin 2
MON1B MON1 secretory trafficking family member B
MRAS muscle RAS oncogene homolog
MTCP1 mature T-cell proliferation 1
MTSS1L metastasis suppressor 1-like
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NGF nerve growth factor (beta polypeptide)
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
OSBP2 oxysterol binding protein 2
OXCT2 3-oxoacid CoA transferase 2
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PARP8 poly (ADP-ribose) polymerase family, member 8
PBOV1 prostate and breast cancer overexpressed 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCOLCE procollagen C-endopeptidase enhancer
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRO2964 uncharacterized protein PRO2964
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RFPL3 ret finger protein-like 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROM1 retinal outer segment membrane protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPS4Y1 ribosomal protein S4, Y-linked 1
SAA3P serum amyloid A3 pseudogene
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPTBN5 spectrin, beta, non-erythrocytic 5
SYP synaptophysin
THAP7 THAP domain containing 7
TMEM180 transmembrane protein 180
TUBA3C tubulin, alpha 3c
WDR4 WD repeat domain 4
WDR62 WD repeat domain 62
ZNF280A zinc finger protein 280A
ZNF768 zinc finger protein 768
ZSCAN2 zinc finger and SCAN domain containing 2
ZXDB zinc finger, X-linked, duplicated B