| Dataset | LINCS L1000 CMAP Chemical Perturbation Consensus Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. (Chemical Entities of Biological Interest Ontology, CHEBI_175901) |
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2 genes differentially expressed following the gemcitabine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3.20595 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PLK1 | polo-like kinase 1 | -3.2361 |
