gemfibrozil-5069 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the gemfibrozil-5069 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ADGRB2 adhesion G protein-coupled receptor B2
AIM2 absent in melanoma 2
AKAP8L A kinase (PRKA) anchor protein 8-like
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP4 aquaporin 4
ARHGAP44 Rho GTPase activating protein 44
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAIAP3 BAI1-associated protein 3
BLK BLK proto-oncogene, Src family tyrosine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C7ORF26 chromosome 7 open reading frame 26
CA9 carbonic anhydrase IX
CADM3 cell adhesion molecule 3
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD5 CD5 molecule
CD58 CD58 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD86 CD86 molecule
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)
CEP295 centrosomal protein 295kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCA1 chloride channel accessory 1
CLDN17 claudin 17
CLEC10A C-type lectin domain family 10, member A
CLEC1A C-type lectin domain family 1, member A
CLEC4A C-type lectin domain family 4, member A
COL14A1 collagen, type XIV, alpha 1
CRYGD crystallin, gamma D
CSHL1 chorionic somatomammotropin hormone-like 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCT dopachrome tautomerase
DGKA diacylglycerol kinase, alpha 80kDa
DTNB dystrobrevin, beta
DUSP1 dual specificity phosphatase 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPHA1 EPH receptor A1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGFR1 fibroblast growth factor receptor 1
FRMPD1 FERM and PDZ domain containing 1
GOLGA8A golgin A8 family, member A
GPR157 G protein-coupled receptor 157
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
IBSP integrin-binding sialoprotein
IGHD immunoglobulin heavy constant delta
IL9R interleukin 9 receptor
ITGA8 integrin, alpha 8
JAG1 jagged 1
JUND jun D proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LAT2 linker for activation of T cells family, member 2
LBX1 ladybird homeobox 1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC399491
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIER2 mesoderm induction early response 1, family member 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
NNAT neuronatin
PACRG PARK2 co-regulated
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARP6 poly (ADP-ribose) polymerase family, member 6
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMEL premelanosome protein
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP1R7 protein phosphatase 1, regulatory subunit 7
PTPRH protein tyrosine phosphatase, receptor type, H
PTPRS protein tyrosine phosphatase, receptor type, S
RAB40A RAB40A, member RAS oncogene family
RAD51 RAD51 recombinase
RAP1GAP RAP1 GTPase activating protein
RBBP9 retinoblastoma binding protein 9
RGS9 regulator of G-protein signaling 9
RHO rhodopsin
RNF126P1 ring finger protein 126 pseudogene 1
RSU1 Ras suppressor protein 1
RUNX1 runt-related transcription factor 1
SCAND2P SCAN domain containing 2 pseudogene
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
TBR1 T-box, brain, 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX3 TOX high mobility group box family member 3
XYLB xylulokinase homolog (H. influenzae)
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARL14 ADP-ribosylation factor-like 14
ARRB2 arrestin, beta 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAG4 BCL2-associated athanogene 4
BEX1 brain expressed, X-linked 1
CA11 carbonic anhydrase XI
CARD8 caspase recruitment domain family, member 8
CBX4 chromobox homolog 4
CBX8 chromobox homolog 8
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD82 CD82 molecule
CFD complement factor D (adipsin)
CIR1 corepressor interacting with RBPJ, 1
CPNE7 copine VII
CRELD1 cysteine-rich with EGF-like domains 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHRS11 dehydrogenase/reductase (SDR family) member 11
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
EN2 engrailed homeobox 2
EPHA4 EPH receptor A4
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC6 excision repair cross-complementation group 6
ETAA1 Ewing tumor-associated antigen 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM188A family with sequence similarity 188, member A
FIG4 FIG4 phosphoinositide 5-phosphatase
FZD3 frizzled class receptor 3
FZD7 frizzled class receptor 7
GID4 GID complex subunit 4
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HIST1H3A histone cluster 1, H3a
HMGB3P1 high mobility group box 3 pseudogene 1
IL15RA interleukin 15 receptor, alpha
INF2 inverted formin, FH2 and WH2 domain containing
KIAA0556 KIAA0556
KIAA0754 KIAA0754
KRT8P12 keratin 8 pseudogene 12
LOC100286895 cell division cycle 27 homolog pseudogene
MB myoglobin
MX1 MX dynamin-like GTPase 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARD6A par-6 family cell polarity regulator alpha
PARM1 prostate androgen-regulated mucin-like protein 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDZK1 PDZ domain containing 1
PER3 period circadian clock 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLH polymerase (DNA directed), eta
POTEKP POTE ankyrin domain family, member K, pseudogene
PRICKLE3 prickle homolog 3 (Drosophila)
PRR15L proline rich 15-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RNF44 ring finger protein 44
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RWDD3 RWD domain containing 3
S100A3 S100 calcium binding protein A3
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC35F6 solute carrier family 35, member F6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNTA1 syntrophin, alpha 1
STEAP4 STEAP family member 4
STIM1 stromal interaction molecule 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEX40 testis expressed 40
TMEM2 transmembrane protein 2
TNNI3 troponin I type 3 (cardiac)
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
TWISTNB TWIST neighbor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YOD1 YOD1 deubiquitinase
ZBTB6 zinc finger and BTB domain containing 6
ZMAT5 zinc finger, matrin-type 5
ZNF204P zinc finger protein 204, pseudogene
ZNF37BP zinc finger protein 37B, pseudogene
ZNF529 zinc finger protein 529
ZNF675 zinc finger protein 675
ZNF84 zinc finger protein 84