genistein-1015 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the genistein-1015 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
AGFG1 ArfGAP with FG repeats 1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ALOX15 arachidonate 15-lipoxygenase
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATXN2L ataxin 2-like
BTN2A2 butyrophilin, subfamily 2, member A2
C11ORF63 chromosome 11 open reading frame 63
C17ORF59 chromosome 17 open reading frame 59
C9ORF9 chromosome 9 open reading frame 9
CA11 carbonic anhydrase XI
CABIN1 calcineurin binding protein 1
CDADC1 cytidine and dCMP deaminase domain containing 1
CNGB3 cyclic nucleotide gated channel beta 3
DALRD3 DALR anticodon binding domain containing 3
DFNB31 deafness, autosomal recessive 31
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGR3 early growth response 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F12 coagulation factor XII (Hageman factor)
FAM131A family with sequence similarity 131, member A
FKBP15 FK506 binding protein 15, 133kDa
GADD45B growth arrest and DNA-damage-inducible, beta
GK3P glycerol kinase 3 pseudogene
GLE1 GLE1 RNA export mediator
GPM6B glycoprotein M6B
GRK5 G protein-coupled receptor kinase 5
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HFE hemochromatosis
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXB6 homeobox B6
ICAM1 intercellular adhesion molecule 1
KLHL18 kelch-like family member 18
LOC157562 uncharacterized LOC157562
LPIN1 lipin 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MED16 mediator complex subunit 16
MGC12488
MTAP methylthioadenosine phosphorylase
MTRF1L mitochondrial translational release factor 1-like
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NBL1 neuroblastoma 1, DAN family BMP antagonist
NF2 neurofibromin 2 (merlin)
NFE2L3 nuclear factor, erythroid 2-like 3
NPFFR1 neuropeptide FF receptor 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PACS1 phosphofurin acidic cluster sorting protein 1
PDE12 phosphodiesterase 12
PDE4DIP phosphodiesterase 4D interacting protein
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDM9 PR domain containing 9
PRDX2 peroxiredoxin 2
PSEN2 presenilin 2
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGES prostaglandin E synthase
RALGDS ral guanine nucleotide dissociation stimulator
RCAN1 regulator of calcineurin 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS3 regulator of G-protein signaling 3
RPGRIP1L RPGRIP1-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RTEL1 regulator of telomere elongation helicase 1
SAPCD1 suppressor APC domain containing 1
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SMA4 glucuronidase, beta pseudogene
SND1-IT1 SND1 intronic transcript 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRD5A3 steroid 5 alpha-reductase 3
STK17A serine/threonine kinase 17a
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAOK1 TAO kinase 1
TCHH trichohyalin
TGFA transforming growth factor, alpha
TJAP1 tight junction associated protein 1 (peripheral)
TLR5 toll-like receptor 5
TMEM242 transmembrane protein 242
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOP3A topoisomerase (DNA) III alpha
TRAK1 trafficking protein, kinesin binding 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZCCHC24 zinc finger, CCHC domain containing 24
ZFAND5 zinc finger, AN1-type domain 5
ZNF10 zinc finger protein 10
ZNF287 zinc finger protein 287
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76
ZNF79 zinc finger protein 79
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD4 abhydrolase domain containing 4
ACVR2B activin A receptor, type IIB
ACYP2 acylphosphatase 2, muscle type
ADGRL2 adhesion G protein-coupled receptor L2
ADORA2B adenosine A2b receptor
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKAP12 A kinase (PRKA) anchor protein 12
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BBS7 Bardet-Biedl syndrome 7
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
CAPN15 calpain 15
CCDC130 coiled-coil domain containing 130
CCNO cyclin O
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CIDEC cell death-inducing DFFA-like effector c
COL9A2 collagen, type IX, alpha 2
CSTA cystatin A (stefin A)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EFHD1 EF-hand domain family, member D1
EHD3 EH-domain containing 3
EPHA4 EPH receptor A4
FAM155B family with sequence similarity 155, member B
FAM179B family with sequence similarity 179, member B
FER fer (fps/fes related) tyrosine kinase
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALK1 galactokinase 1
GJA1 gap junction protein, alpha 1, 43kDa
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HIST1H2AJ histone cluster 1, H2aj
HPSE heparanase
ITPKB inositol-trisphosphate 3-kinase B
KAT2A K(lysine) acetyltransferase 2A
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA0895 KIAA0895
LAMB3 laminin, beta 3
LINC00339 long intergenic non-protein coding RNA 339
LMBR1L limb development membrane protein 1-like
LMNB1 lamin B1
LNPEP leucyl/cystinyl aminopeptidase
LOC730101 uncharacterized LOC730101
LYPLA2P1 lysophospholipase II pseudogene 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
METTL16 methyltransferase like 16
MEX3C mex-3 RNA binding family member C
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD11 major facilitator superfamily domain containing 11
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MNT MAX network transcriptional repressor
NUAK1 NUAK family, SNF1-like kinase, 1
P3H1 prolyl 3-hydroxylase 1
PBLD phenazine biosynthesis-like protein domain containing
PCNXL4 pecanex-like 4 (Drosophila)
PEX12 peroxisomal biogenesis factor 12
PGAP1 post-GPI attachment to proteins 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
POTEKP POTE ankyrin domain family, member K, pseudogene
PRMT7 protein arginine methyltransferase 7
PTBP2 polypyrimidine tract binding protein 2
PTDSS2 phosphatidylserine synthase 2
RABL6 RAB, member RAS oncogene family-like 6
RBL1 retinoblastoma-like 1
RGS17 regulator of G-protein signaling 17
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SALL2 spalt-like transcription factor 2
SHARPIN SHANK-associated RH domain interactor
SLC25A40 solute carrier family 25, member 40
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
STARD5 StAR-related lipid transfer (START) domain containing 5
STBD1 starch binding domain 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYCP2 synaptonemal complex protein 2
SYT17 synaptotagmin XVII
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
VAV3 vav 3 guanine nucleotide exchange factor
ZBTB3 zinc finger and BTB domain containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF226 zinc finger protein 226
ZNF280D zinc finger protein 280D
ZNF408 zinc finger protein 408
ZNF668 zinc finger protein 668
ZNF721 zinc finger protein 721
ZNF770 zinc finger protein 770