genistein-1073 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the genistein-1073 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
ACTL6A actin-like 6A
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
AREG amphiregulin
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX3 armadillo repeat containing, X-linked 3
ATG13 autophagy related 13
AZI2 5-azacytidine induced 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BRAF B-Raf proto-oncogene, serine/threonine kinase
C12ORF29 chromosome 12 open reading frame 29
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CBY1 chibby homolog 1 (Drosophila)
CENPQ centromere protein Q
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIC capicua transcriptional repressor
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPT2 carnitine palmitoyltransferase 2
CXORF56 chromosome X open reading frame 56
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DND1 DND microRNA-mediated repression inhibitor 1
EGR3 early growth response 3
ELF1 E74-like factor 1 (ets domain transcription factor)
EXOC7 exocyst complex component 7
FAM53B family with sequence similarity 53, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GALK2 galactokinase 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLI3 GLI family zinc finger 3
GNL1 guanine nucleotide binding protein-like 1
HOMER2 homer scaffolding protein 2
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
INO80B INO80 complex subunit B
INSIG1 insulin induced gene 1
ISOC1 isochorismatase domain containing 1
ITM2B integral membrane protein 2B
KIF3C kinesin family member 3C
KLF5 Kruppel-like factor 5 (intestinal)
KLHL2 kelch-like family member 2
KLHL22 kelch-like family member 22
MADD MAP-kinase activating death domain
MAGEF1 melanoma antigen family F1
MANEA mannosidase, endo-alpha
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NAP1L1 nucleosome assembly protein 1-like 1
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NDRG4 NDRG family member 4
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
OGFR opioid growth factor receptor
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX14 peroxisomal biogenesis factor 14
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PQLC1 PQ loop repeat containing 1
RAD17 RAD17 homolog (S. pombe)
RFK riboflavin kinase
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS2 ribosomal protein S2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A11 S100 calcium binding protein A11
SCAMP1 secretory carrier membrane protein 1
SEC23B Sec23 homolog B (S. cerevisiae)
SESN1 sestrin 1
SGK1 serum/glucocorticoid regulated kinase 1
SIAH1 siah E3 ubiquitin protein ligase 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC38A10 solute carrier family 38, member 10
SMC2 structural maintenance of chromosomes 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMOX spermine oxidase
SND1-IT1 SND1 intronic transcript 1
SOCS5 suppressor of cytokine signaling 5
SPAG4 sperm associated antigen 4
SSR2 signal sequence receptor, beta (translocon-associated protein beta)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STX2 syntaxin 2
SVIL supervillin
TBCD tubulin folding cofactor D
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM80 transmembrane protein 80
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPCN1 two pore segment channel 1
TSPAN31 tetraspanin 31
TUSC2 tumor suppressor candidate 2
TWF2 twinfilin actin binding protein 2
UNC119 unc-119 homolog (C. elegans)
ZBED1 zinc finger, BED-type containing 1
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMC7 armadillo repeat containing 7
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
BATF basic leucine zipper transcription factor, ATF-like
C16ORF59 chromosome 16 open reading frame 59
C1ORF56 chromosome 1 open reading frame 56
C2CD2 C2 calcium-dependent domain containing 2
C5 complement component 5
CALHM2 calcium homeostasis modulator 2
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CBR3 carbonyl reductase 3
CENPJ centromere protein J
CIR1 corepressor interacting with RBPJ, 1
CLASRP CLK4-associating serine/arginine rich protein
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COG4 component of oligomeric golgi complex 4
CTNNBL1 catenin, beta like 1
DENND4C DENN/MADD domain containing 4C
DGKD diacylglycerol kinase, delta 130kDa
DNA2 DNA replication helicase/nuclease 2
EDC4 enhancer of mRNA decapping 4
EFNA1 ephrin-A1
FAM160B2 family with sequence similarity 160, member B2
FAM32A family with sequence similarity 32, member A
FBXO46 F-box protein 46
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GCC1 GRIP and coiled-coil domain containing 1
GHR growth hormone receptor
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
HCFC2 host cell factor C2
HOXC11 homeobox C11
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFT88 intraflagellar transport 88
INF2 inverted formin, FH2 and WH2 domain containing
IRAK4 interleukin-1 receptor-associated kinase 4
IREB2 iron-responsive element binding protein 2
ISG15 ISG15 ubiquitin-like modifier
KCTD15 potassium channel tetramerization domain containing 15
KDM5C lysine (K)-specific demethylase 5C
LAMB2 laminin, beta 2 (laminin S)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC42 leucine rich repeat containing 42
LUC7L LUC7-like (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MOCS3 molybdenum cofactor synthesis 3
MTCH1 mitochondrial carrier 1
MYLIP myosin regulatory light chain interacting protein
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NSD1 nuclear receptor binding SET domain protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
OFD1 oral-facial-digital syndrome 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDZRN3 PDZ domain containing ring finger 3
PEX12 peroxisomal biogenesis factor 12
PMCH pro-melanin-concentrating hormone
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP6R3 protein phosphatase 6, regulatory subunit 3
RAB32 RAB32, member RAS oncogene family
RBM15B RNA binding motif protein 15B
REPS2 RALBP1 associated Eps domain containing 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SAMHD1 SAM domain and HD domain 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A6 solute carrier family 16, member 6
SLC25A40 solute carrier family 25, member 40
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SMA4 glucuronidase, beta pseudogene
SP140L SP140 nuclear body protein-like
SYTL2 synaptotagmin-like 2
TBL3 transducin (beta)-like 3
TET3 tet methylcytosine dioxygenase 3
THAP4 THAP domain containing 4
THRAP3 thyroid hormone receptor associated protein 3
TMEM57 transmembrane protein 57
TRAF5 TNF receptor-associated factor 5
TRAPPC2 trafficking protein particle complex 2
TSPAN15 tetraspanin 15
TXNL4B thioredoxin-like 4B
ZNF165 zinc finger protein 165
ZNF675 zinc finger protein 675
ZNF721 zinc finger protein 721
ZNF91 zinc finger protein 91
ZNHIT2 zinc finger, HIT-type containing 2