genistein-1176 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the genistein-1176 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD3 abhydrolase domain containing 3
ADAP2 ArfGAP with dual PH domains 2
ADGRE2 adhesion G protein-coupled receptor E2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APOLD1 apolipoprotein L domain containing 1
APP amyloid beta (A4) precursor protein
AREG amphiregulin
ARNT aryl hydrocarbon receptor nuclear translocator
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BLZF1 basic leucine zipper nuclear factor 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CD86 CD86 molecule
CHN2 chimerin 2
CLCA1 chloride channel accessory 1
CREM cAMP responsive element modulator
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOCK4 dedicator of cytokinesis 4
DUSP4 dual specificity phosphatase 4
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EGR3 early growth response 3
EIF1 eukaryotic translation initiation factor 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELF2 E74-like factor 2 (ets domain transcription factor)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERAP1 endoplasmic reticulum aminopeptidase 1
FH fumarate hydratase
FOS FBJ murine osteosarcoma viral oncogene homolog
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GLIPR1 GLI pathogenesis-related 1
GPR183 G protein-coupled receptor 183
HBEGF heparin-binding EGF-like growth factor
HOXA9 homeobox A9
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
INHBA inhibin, beta A
ISG20 interferon stimulated exonuclease gene 20kDa
KIAA0753 KIAA0753
KLF6 Kruppel-like factor 6
KYNU kynureninase
LMAN1 lectin, mannose-binding, 1
LOC642236 FSHD region gene 1 pseudogene
LRP12 low density lipoprotein receptor-related protein 12
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP2K3 mitogen-activated protein kinase kinase 3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCL1 myeloid cell leukemia 1
MCTP2 multiple C2 domains, transmembrane 2
MED20 mediator complex subunit 20
MOB1A MOB kinase activator 1A
MPZL1 myelin protein zero-like 1
MT1HL1 metallothionein 1H-like 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLK nemo-like kinase
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PAM peptidylglycine alpha-amidating monooxygenase
PCYOX1 prenylcysteine oxidase 1
PDE4B phosphodiesterase 4B, cAMP-specific
PEX11A peroxisomal biogenesis factor 11 alpha
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAGL1 pleiomorphic adenoma gene-like 1
PLSCR1 phospholipid scramblase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOB ras homolog family member B
RPS9 ribosomal protein S9
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SNX15 sorting nexin 15
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SPAST spastin
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STAT2 signal transducer and activator of transcription 2, 113kDa
STX5 syntaxin 5
SYNJ2BP synaptojanin 2 binding protein
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TEX261 testis expressed 261
THBS1 thrombospondin 1
VAMP4 vesicle-associated membrane protein 4
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC11 zinc finger, CCHC domain containing 11
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALPK1 alpha-kinase 1
ANKRD55 ankyrin repeat domain 55
ARMC7 armadillo repeat containing 7
B3GNT1
BRD9 bromodomain containing 9
C10ORF2 chromosome 10 open reading frame 2
C14ORF159 chromosome 14 open reading frame 159
C19ORF24 chromosome 19 open reading frame 24
C2CD2 C2 calcium-dependent domain containing 2
CA2 carbonic anhydrase II
CCDC86 coiled-coil domain containing 86
CCNA1 cyclin A1
CDIP1 cell death-inducing p53 target 1
CDK5 cyclin-dependent kinase 5
CLSPN claspin
CTSG cathepsin G
DEAF1 DEAF1 transcription factor
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DPH2 DPH2 homolog (S. cerevisiae)
EFCAB2 EF-hand calcium binding domain 2
ELP6 elongator acetyltransferase complex subunit 6
ENDOG endonuclease G
EVL Enah/Vasp-like
FAM53B family with sequence similarity 53, member B
FAM86B1 family with sequence similarity 86, member B1
FBXL7 F-box and leucine-rich repeat protein 7
FERMT1 fermitin family member 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GSE1 Gse1 coiled-coil protein
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
IFRD2 interferon-related developmental regulator 2
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KIAA0754 KIAA0754
KIAA0930 KIAA0930
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRC37A3 leucine rich repeat containing 37, member A3
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAK16 MAK16 homolog (S. cerevisiae)
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRPL12 mitochondrial ribosomal protein L12
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NABP2 nucleic acid binding protein 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NFE2 nuclear factor, erythroid 2
NLRX1 NLR family member X1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSD1 nuclear receptor binding SET domain protein 1
NTHL1 nth endonuclease III-like 1 (E. coli)
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PARPBP PARP1 binding protein
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PELP1 proline, glutamate and leucine rich protein 1
PFKM phosphofructokinase, muscle
PFKP phosphofructokinase, platelet
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRTN3 proteinase 3
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
PYCR1 pyrroline-5-carboxylate reductase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFPL1S RFPL1 antisense RNA 1
RNF122 ring finger protein 122
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUVBL1 RuvB-like AAA ATPase 1
SALL2 spalt-like transcription factor 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIPA1 signal-induced proliferation-associated 1
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SPATA2L spermatogenesis associated 2-like
SRM spermidine synthase
STBD1 starch binding domain 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TELO2 telomere maintenance 2
TERT telomerase reverse transcriptase
THBS4 thrombospondin 4
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TTLL12 tubulin tyrosine ligase-like family member 12
URGCP upregulator of cell proliferation
VILL villin-like
WDR46 WD repeat domain 46
XYLT2 xylosyltransferase II
ZNF692 zinc finger protein 692