| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the genistein-1235 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AHI1 | Abelson helper integration site 1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| BBC3 | BCL2 binding component 3 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C1R | complement component 1, r subcomponent |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCDC132 | coiled-coil domain containing 132 |
| CD1E | CD1e molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDC14B | cell division cycle 14B |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHMP6 | charged multivesicular body protein 6 |
| COL1A2 | collagen, type I, alpha 2 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DOCK6 | dedicator of cytokinesis 6 |
| DPYS | dihydropyrimidinase |
| EPOR | erythropoietin receptor |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FBLN1 | fibulin 1 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGF23 | fibroblast growth factor 23 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GPC3 | glypican 3 |
| GYG2 | glycogenin 2 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4D | histone cluster 1, H4d |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL11 | interleukin 11 |
| INO80B | INO80 complex subunit B |
| KIF13A | kinesin family member 13A |
| KIF1A | kinesin family member 1A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLK10 | kallikrein-related peptidase 10 |
| KRT9 | keratin 9, type I |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIPG | lipase, endothelial |
| LMF2 | lipase maturation factor 2 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NKTR | natural killer cell triggering receptor |
| NMT1 | N-myristoyltransferase 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDS5B | PDS5 cohesin associated factor B |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PKP3 | plakophilin 3 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGES2 | prostaglandin E synthase 2 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SC5D | sterol-C5-desaturase |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SERHL2 | serine hydrolase-like 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SHPK | sedoheptulokinase |
| SRCAP | Snf2-related CREBBP activator protein |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNGR1 | synaptogyrin 1 |
| TAOK2 | TAO kinase 2 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TDRKH | tudor and KH domain containing |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TMEM259 | transmembrane protein 259 |
| TMF1 | TATA element modulatory factor 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBOX5 | U-box domain containing 5 |
| UGT8 | UDP glycosyltransferase 8 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VCX2 | variable charge, X-linked 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF358 | zinc finger protein 358 |
| ZNF76 | zinc finger protein 76 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTN4 | actinin, alpha 4 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AEN | apoptosis enhancing nuclease |
| AFAP1 | actin filament associated protein 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CCDC85C | coiled-coil domain containing 85C |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD70 | CD70 molecule |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CORO2A | coronin, actin binding protein, 2A |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DMTN | dematin actin binding protein |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFHD2 | EF-hand domain family, member D2 |
| EFNA3 | ephrin-A3 |
| GLCE | glucuronic acid epimerase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH3 | G patch domain containing 3 |
| HIST1H3G | histone cluster 1, H3g |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXC10 | homeobox C10 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL17RA | interleukin 17 receptor A |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0355 | KIAA0355 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MANEA | mannosidase, endo-alpha |
| MED9 | mediator complex subunit 9 |
| MXD3 | MAX dimerization protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NME5 | NME/NM23 family member 5 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDZD2 | PDZ domain containing 2 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRPF38B | pre-mRNA processing factor 38B |
| REEP4 | receptor accessory protein 4 |
| RNF122 | ring finger protein 122 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCEL | sciellin |
| SCG5 | secretogranin V |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERTAD3 | SERTA domain containing 3 |
| SETD1B | SET domain containing 1B |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SPEG | SPEG complex locus |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNPO | synaptopodin |
| TCTN1 | tectonic family member 1 |
| TCTN2 | tectonic family member 2 |
| TGFB3 | transforming growth factor, beta 3 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TRIM9 | tripartite motif containing 9 |
| TSPAN15 | tetraspanin 15 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| USP6 | ubiquitin specific peptidase 6 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR18 | WD repeat domain 18 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF107 | zinc finger protein 107 |
| ZNF280D | zinc finger protein 280D |
| ZNF408 | zinc finger protein 408 |
| ZXDC | ZXD family zinc finger C |