genistein-1235 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the genistein-1235 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
AGGF1 angiogenic factor with G patch and FHA domains 1
AHI1 Abelson helper integration site 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BBC3 BCL2 binding component 3
C1QL1 complement component 1, q subcomponent-like 1
C1R complement component 1, r subcomponent
C22ORF29 chromosome 22 open reading frame 29
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC132 coiled-coil domain containing 132
CD1E CD1e molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC14B cell division cycle 14B
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP6 charged multivesicular body protein 6
COL1A2 collagen, type I, alpha 2
DHODH dihydroorotate dehydrogenase (quinone)
DNAAF1 dynein, axonemal, assembly factor 1
DOCK6 dedicator of cytokinesis 6
DPYS dihydropyrimidinase
EPOR erythropoietin receptor
ERO1LB ERO1-like beta (S. cerevisiae)
FBLN1 fibulin 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF23 fibroblast growth factor 23
FGFR1 fibroblast growth factor receptor 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPC3 glypican 3
GYG2 glycogenin 2
HAUS5 HAUS augmin-like complex, subunit 5
HIST1H2BN histone cluster 1, H2bn
HIST1H4D histone cluster 1, H4d
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGF1R insulin-like growth factor 1 receptor
IL11 interleukin 11
INO80B INO80 complex subunit B
KIF13A kinesin family member 13A
KIF1A kinesin family member 1A
KLF3 Kruppel-like factor 3 (basic)
KLK10 kallikrein-related peptidase 10
KRT9 keratin 9, type I
LIG3 ligase III, DNA, ATP-dependent
LIPG lipase, endothelial
LMF2 lipase maturation factor 2
LPCAT3 lysophosphatidylcholine acyltransferase 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPS12 mitochondrial ribosomal protein S12
MUC5B mucin 5B, oligomeric mucus/gel-forming
NCAPH2 non-SMC condensin II complex, subunit H2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NKTR natural killer cell triggering receptor
NMT1 N-myristoyltransferase 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OASL 2'-5'-oligoadenylate synthetase-like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAIP2B poly(A) binding protein interacting protein 2B
PDS5B PDS5 cohesin associated factor B
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PKP3 plakophilin 3
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PSD4 pleckstrin and Sec7 domain containing 4
PTGES2 prostaglandin E synthase 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RPP25 ribonuclease P/MRP 25kDa subunit
SC5D sterol-C5-desaturase
SCAND2P SCAN domain containing 2 pseudogene
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERHL2 serine hydrolase-like 2
SETD8 SET domain containing (lysine methyltransferase) 8
SHPK sedoheptulokinase
SRCAP Snf2-related CREBBP activator protein
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNGR1 synaptogyrin 1
TAOK2 TAO kinase 2
TAS2R1 taste receptor, type 2, member 1
TDRKH tudor and KH domain containing
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TMEM259 transmembrane protein 259
TMF1 TATA element modulatory factor 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
U2AF2 U2 small nuclear RNA auxiliary factor 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBOX5 U-box domain containing 5
UGT8 UDP glycosyltransferase 8
USF2 upstream transcription factor 2, c-fos interacting
VCX2 variable charge, X-linked 2
WFDC2 WAP four-disulfide core domain 2
WNK1 WNK lysine deficient protein kinase 1
ZNF358 zinc finger protein 358
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTN4 actinin, alpha 4
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AEN apoptosis enhancing nuclease
AFAP1 actin filament associated protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C3ORF52 chromosome 3 open reading frame 52
CCDC85C coiled-coil domain containing 85C
CCL20 chemokine (C-C motif) ligand 20
CD70 CD70 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CORO2A coronin, actin binding protein, 2A
CSRNP3 cysteine-serine-rich nuclear protein 3
CTNNBIP1 catenin, beta interacting protein 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DMTN dematin actin binding protein
DNAAF2 dynein, axonemal, assembly factor 2
EDC4 enhancer of mRNA decapping 4
EFHD2 EF-hand domain family, member D2
EFNA3 ephrin-A3
GLCE glucuronic acid epimerase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
HIST1H3G histone cluster 1, H3g
HIST2H2AA3 histone cluster 2, H2aa3
HOXC10 homeobox C10
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
ITPKC inositol-trisphosphate 3-kinase C
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0355 KIAA0355
LPAR3 lysophosphatidic acid receptor 3
LYPD1 LY6/PLAUR domain containing 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MANEA mannosidase, endo-alpha
MED9 mediator complex subunit 9
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NME5 NME/NM23 family member 5
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARD6A par-6 family cell polarity regulator alpha
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDZD2 PDZ domain containing 2
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POMT2 protein-O-mannosyltransferase 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRPF38B pre-mRNA processing factor 38B
REEP4 receptor accessory protein 4
RNF122 ring finger protein 122
RUSC2 RUN and SH3 domain containing 2
SCAMP5 secretory carrier membrane protein 5
SCEL sciellin
SCG5 secretogranin V
SCUBE3 signal peptide, CUB domain, EGF-like 3
SENP7 SUMO1/sentrin specific peptidase 7
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERTAD3 SERTA domain containing 3
SETD1B SET domain containing 1B
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SPEG SPEG complex locus
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SUN2 Sad1 and UNC84 domain containing 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNPO synaptopodin
TCTN1 tectonic family member 1
TCTN2 tectonic family member 2
TGFB3 transforming growth factor, beta 3
TGFBI transforming growth factor, beta-induced, 68kDa
TINAGL1 tubulointerstitial nephritis antigen-like 1
TRIM9 tripartite motif containing 9
TSPAN15 tetraspanin 15
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USP6 ubiquitin specific peptidase 6
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR18 WD repeat domain 18
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF107 zinc finger protein 107
ZNF280D zinc finger protein 280D
ZNF408 zinc finger protein 408
ZXDC ZXD family zinc finger C