genistein-268 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the genistein-268 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACAA2 acetyl-CoA acyltransferase 2
ADAM12 ADAM metallopeptidase domain 12
ADAM22 ADAM metallopeptidase domain 22
ADAP1 ArfGAP with dual PH domains 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGAP19 Rho GTPase activating protein 19
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BTD biotinidase
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
CA9 carbonic anhydrase IX
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPN10 calpain 10
CBX2 chromobox homolog 2
CHPF2 chondroitin polymerizing factor 2
CHRM4 cholinergic receptor, muscarinic 4
CLASP2 cytoplasmic linker associated protein 2
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRYAA crystallin, alpha A
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DUS2 dihydrouridine synthase 2
DXO decapping exoribonuclease
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EHD2 EH-domain containing 2
ERCC1 excision repair cross-complementation group 1
ESR2 estrogen receptor 2 (ER beta)
FGFR2 fibroblast growth factor receptor 2
FRMD1 FERM domain containing 1
FSD1 fibronectin type III and SPRY domain containing 1
FXR2 fragile X mental retardation, autosomal homolog 2
GADD45B growth arrest and DNA-damage-inducible, beta
GEMIN4 gem (nuclear organelle) associated protein 4
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GK glycerol kinase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR19 G protein-coupled receptor 19
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA4 heat shock 70kDa protein 4
IFFO1 intermediate filament family orphan 1
IFI27 interferon, alpha-inducible protein 27
IL9R interleukin 9 receptor
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
LAMA3 laminin, alpha 3
LIG3 ligase III, DNA, ATP-dependent
LMF1 lipase maturation factor 1
LUZP2 leucine zipper protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MARC1 mitochondrial amidoxime reducing component 1
MBNL2 muscleblind-like splicing regulator 2
MED1 mediator complex subunit 1
MED14 mediator complex subunit 14
MICB MHC class I polypeptide-related sequence B
MON1B MON1 secretory trafficking family member B
MPPE1 metallophosphoesterase 1
N4BP1 NEDD4 binding protein 1
NRGN neurogranin (protein kinase C substrate, RC3)
NUPL2 nucleoporin like 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PARVA parvin, alpha
PCDHB3 protocadherin beta 3
PGBD5 piggyBac transposable element derived 5
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPARD peroxisome proliferator-activated receptor delta
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
RAB33B RAB33B, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RECQL5 RecQ protein-like 5
RNF24 ring finger protein 24
RRBP1 ribosome binding protein 1
RREB1 ras responsive element binding protein 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SGK1 serum/glucocorticoid regulated kinase 1
SH3BP2 SH3-domain binding protein 2
SHB Src homology 2 domain containing adaptor protein B
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX1 synovial sarcoma, X breakpoint 1
STK19 serine/threonine kinase 19
SURF2 surfeit 2
TFE3 transcription factor binding to IGHM enhancer 3
TMPRSS2 transmembrane protease, serine 2
TRIM23 tripartite motif containing 23
TSSK2 testis-specific serine kinase 2
TTLL4 tubulin tyrosine ligase-like family member 4
UBE4B ubiquitination factor E4B
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR13 WD repeat domain 13
WDR18 WD repeat domain 18
XYLT2 xylosyltransferase II
YIPF6 Yip1 domain family, member 6
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AGMAT agmatine ureohydrolase (agmatinase)
AK5 adenylate kinase 5
ALOX15B arachidonate 15-lipoxygenase, type B
ALPK1 alpha-kinase 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARSF arylsulfatase F
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN2L ataxin 2-like
ATXN3L ataxin 3-like
BCAS1 breast carcinoma amplified sequence 1
BDKRB1 bradykinin receptor B1
BEST2 bestrophin 2
C17ORF53 chromosome 17 open reading frame 53
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CADPS Ca++-dependent secretion activator
CD5 CD5 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CHD5 chromodomain helicase DNA binding protein 5
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLSTN2 calsyntenin 2
CNTNAP1 contactin associated protein 1
COL9A2 collagen, type IX, alpha 2
DNASE1L2 deoxyribonuclease I-like 2
DRP2 dystrophin related protein 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFCAB1 EF-hand calcium binding domain 1
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
EYA1 EYA transcriptional coactivator and phosphatase 1
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
G0S2 G0/G1 switch 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GALR3 galanin receptor 3
GATA1 GATA binding protein 1 (globin transcription factor 1)
GJC1 gap junction protein, gamma 1, 45kDa
GLB1L galactosidase, beta 1-like
GRIP2 glutamate receptor interacting protein 2
GRM2 glutamate receptor, metabotropic 2
GUCA1B guanylate cyclase activator 1B (retina)
GUSBP3 glucuronidase, beta pseudogene 3
HAVCR1 hepatitis A virus cellular receptor 1
HOPX HOP homeobox
HOXB1 homeobox B1
HRH2 histamine receptor H2
HSPB3 heat shock 27kDa protein 3
IL12RB1 interleukin 12 receptor, beta 1
KLHL3 kelch-like family member 3
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LRRC17 leucine rich repeat containing 17
MAGEB2 melanoma antigen family B2
MEGF6 multiple EGF-like-domains 6
MFSD11 major facilitator superfamily domain containing 11
MLXIPL MLX interacting protein-like
MYBPC3 myosin binding protein C, cardiac
NCKAP1L NCK-associated protein 1-like
NIPAL2 NIPA-like domain containing 2
ONECUT1 one cut homeobox 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDZD7 PDZ domain containing 7
PELP1 proline, glutamate and leucine rich protein 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PNOC prepronociceptin
PRDM14 PR domain containing 14
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
PRSS53 protease, serine, 53
PTPRN protein tyrosine phosphatase, receptor type, N
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
S1PR4 sphingosine-1-phosphate receptor 4
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP1 SH3-domain binding protein 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMO smoothened, frizzled class receptor
SPRYD7 SPRY domain containing 7
TAGLN transgelin
TEX13B testis expressed 13B
TGM5 transglutaminase 5
TMEM176A transmembrane protein 176A
TMPRSS4 transmembrane protease, serine 4
TSPAN15 tetraspanin 15
TSPAN32 tetraspanin 32
TUBA4B tubulin, alpha 4b
UBTD1 ubiquitin domain containing 1
USP20 ubiquitin specific peptidase 20
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT2 wingless-type MMTV integration site family member 2