genistein-2695 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the genistein-2695 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADIRF adipogenesis regulatory factor
ALOX5 arachidonate 5-lipoxygenase
AXL AXL receptor tyrosine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C16ORF45 chromosome 16 open reading frame 45
CALD1 caldesmon 1
CCDC40 coiled-coil domain containing 40
CCL20 chemokine (C-C motif) ligand 20
CDH10 cadherin 10, type 2 (T2-cadherin)
CDO1 cysteine dioxygenase type 1
COL9A3 collagen, type IX, alpha 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREM cAMP responsive element modulator
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DOCK4 dedicator of cytokinesis 4
DUSP4 dual specificity phosphatase 4
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EDN3 endothelin 3
EGR1 early growth response 1
EVI5 ecotropic viral integration site 5
FAM149B1 family with sequence similarity 149, member B1
FAM182A family with sequence similarity 182, member A
FLOT1 flotillin 1
FOXO4 forkhead box O4
FTH1 ferritin, heavy polypeptide 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GEM GTP binding protein overexpressed in skeletal muscle
GPC3 glypican 3
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRM1 glutamate receptor, metabotropic 1
HOXD10 homeobox D10
HPCA hippocalcin
HRH1 histamine receptor H1
HSPA2 heat shock 70kDa protein 2
HSPB3 heat shock 27kDa protein 3
IFT54 intraflagellar transport 54
ISG20 interferon stimulated exonuclease gene 20kDa
JPH3 junctophilin 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF1C kinesin family member 1C
KYNU kynureninase
LOC257152 uncharacterized LOC257152
LTBP2 latent transforming growth factor beta binding protein 2
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL2 muscleblind-like splicing regulator 2
MCTP2 multiple C2 domains, transmembrane 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MOBP myelin-associated oligodendrocyte basic protein
MUC3B mucin 3B, cell surface associated
N4BP2L2 NEDD4 binding protein 2-like 2
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NEUROG2 neurogenin 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOTCH4 notch 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRG1 neuregulin 1
NTN1 netrin 1
PADI4 peptidyl arginine deiminase, type IV
PAX8 paired box 8
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM3 PDZ and LIM domain 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLSCR1 phospholipid scramblase 1
PLVAP plasmalemma vesicle associated protein
PPAP2B phosphatidic acid phosphatase type 2B
PPARD peroxisome proliferator-activated receptor delta
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKCQ protein kinase C, theta
PRO2964 uncharacterized protein PRO2964
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBPMS RNA binding protein with multiple splicing
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC16A4 solute carrier family 16, member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX11 syntaxin 11
SUGCT succinyl-CoA:glutarate-CoA transferase
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TAPT1 transmembrane anterior posterior transformation 1
TCAF1 TRPM8 channel-associated factor 1
THBS1 thrombospondin 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRPS1 trichorhinophalangeal syndrome I
TUBB2A tubulin, beta 2A class IIa
ZER1 zyg-11 related, cell cycle regulator
ZNF385D zinc finger protein 385D
ZNF415 zinc finger protein 415

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AMT aminomethyltransferase
ANKRD55 ankyrin repeat domain 55
ANKRD7 ankyrin repeat domain 7
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASGR2 asialoglycoprotein receptor 2
AXIN1 axin 1
BBC3 BCL2 binding component 3
BCAS3 breast carcinoma amplified sequence 3
C19ORF73 chromosome 19 open reading frame 73
CCL2 chemokine (C-C motif) ligand 2
CD160 CD160 molecule
CDK3 cyclin-dependent kinase 3
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLCF1 cardiotrophin-like cytokine factor 1
CLGN calmegin
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEPDC5 DEP domain containing 5
ENO3 enolase 3 (beta, muscle)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FLT3 fms-related tyrosine kinase 3
FMOD fibromodulin
FOXN2 forkhead box N2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GIF gastric intrinsic factor (vitamin B synthesis)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC1 glypican 1
GSTT1 glutathione S-transferase theta 1
HDAC9 histone deacetylase 9
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HOPX HOP homeobox
HYAL3 hyaluronoglucosaminidase 3
IFNA14 interferon, alpha 14
INHBE inhibin, beta E
IRF8 interferon regulatory factor 8
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDM8 lysine (K)-specific demethylase 8
KRT8P12 keratin 8 pseudogene 12
LRP5 low density lipoprotein receptor-related protein 5
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MARC1 mitochondrial amidoxime reducing component 1
MATK megakaryocyte-associated tyrosine kinase
MED22 mediator complex subunit 22
MED9 mediator complex subunit 9
MEST mesoderm specific transcript
MMP9 matrix metallopeptidase 9
MNX1 motor neuron and pancreas homeobox 1
MRPL28 mitochondrial ribosomal protein L28
MXD3 MAX dimerization protein 3
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OCLN occludin
OVGP1 oviductal glycoprotein 1, 120kDa
PARP16 poly (ADP-ribose) polymerase family, member 16
PCBP4 poly(rC) binding protein 4
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLA2G15 phospholipase A2, group XV
PRDM12 PR domain containing 12
PRICKLE3 prickle homolog 3 (Drosophila)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PYGB phosphorylase, glycogen; brain
RHOH ras homolog family member H
RIN1 Ras and Rab interactor 1
RNF25 ring finger protein 25
RPL23AP7 ribosomal protein L23a pseudogene 7
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
S100A12 S100 calcium binding protein A12
SALL2 spalt-like transcription factor 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC16A6 solute carrier family 16, member 6
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A14 solute carrier family 22, member 14
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLITRK5 SLIT and NTRK-like family, member 5
SLPI secretory leukocyte peptidase inhibitor
STC2 stanniocalcin 2
STEAP4 STEAP family member 4
TAGLN transgelin
TEC tec protein tyrosine kinase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM212 transmembrane protein 212
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEZT vezatin, adherens junctions transmembrane protein
WNT10B wingless-type MMTV integration site family, member 10B
ZNF276 zinc finger protein 276
ZNF350 zinc finger protein 350
ZNF692 zinc finger protein 692
ZNF696 zinc finger protein 696
ZNHIT2 zinc finger, HIT-type containing 2