genistein-382 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the genistein-382 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
APOA1 apolipoprotein A-I
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARRB2 arrestin, beta 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG12 autophagy related 12
BAGE B melanoma antigen
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC87 coiled-coil domain containing 87
CDC25A cell division cycle 25A
CEP131 centrosomal protein 131kDa
COMMD9 COMM domain containing 9
CPD carboxypeptidase D
CRIPT cysteine-rich PDZ-binding protein
DHPS deoxyhypusine synthase
DIXDC1 DIX domain containing 1
DOC2B double C2-like domains, beta
DOPEY1 dopey family member 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECE1 endothelin converting enzyme 1
EMC1 ER membrane protein complex subunit 1
EPHA4 EPH receptor A4
EPX eosinophil peroxidase
ESR1 estrogen receptor 1
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
FBLN1 fibulin 1
FLJ42627 uncharacterized LOC645644
FRMD1 FERM domain containing 1
FSD1 fibronectin type III and SPRY domain containing 1
FXR2 fragile X mental retardation, autosomal homolog 2
GABPB1 GA binding protein transcription factor, beta subunit 1
GADD45B growth arrest and DNA-damage-inducible, beta
GAS8 growth arrest-specific 8
GDF11 growth differentiation factor 11
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLG1 golgi glycoprotein 1
GLI3 GLI family zinc finger 3
GLRX glutaredoxin (thioltransferase)
GPC1 glypican 1
GPR107 G protein-coupled receptor 107
HIRIP3 HIRA interacting protein 3
HIST1H3G histone cluster 1, H3g
HIST1H4J histone cluster 1, H4j
HN1L hematological and neurological expressed 1-like
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL15RA interleukin 15 receptor, alpha
KIAA0040 KIAA0040
LMF2 lipase maturation factor 2
MAGOHB mago-nashi homolog B (Drosophila)
MBNL2 muscleblind-like splicing regulator 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NADK NAD kinase
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NOL6 nucleolar protein 6 (RNA-associated)
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OXLD1 oxidoreductase-like domain containing 1
PCDHB6 protocadherin beta 6
PCGF1 polycomb group ring finger 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PEX14 peroxisomal biogenesis factor 14
PIAS4 protein inhibitor of activated STAT, 4
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRRC2B proline-rich coiled-coil 2B
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RALBP1 ralA binding protein 1
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RBL2 retinoblastoma-like 2
RNF186 ring finger protein 186
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPS2 ribosomal protein S2
RUNX2 runt-related transcription factor 2
SIRPA signal-regulatory protein alpha
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SNX10 sorting nexin 10
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SYF2 SYF2 pre-mRNA-splicing factor
SZRD1 SUZ RNA binding domain containing 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TMEM187 transmembrane protein 187
TMEM70 transmembrane protein 70
TOB2 transducer of ERBB2, 2
TOE1 target of EGR1, member 1 (nuclear)
TSFM Ts translation elongation factor, mitochondrial
TSPO2 translocator protein 2
TUBGCP3 tubulin, gamma complex associated protein 3
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VRK3 vaccinia related kinase 3
WDR46 WD repeat domain 46
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADRA2B adrenoceptor alpha 2B
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMN amnion associated transmembrane protein
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATG10 autophagy related 10
BTBD2 BTB (POZ) domain containing 2
C14ORF132 chromosome 14 open reading frame 132
C19ORF66 chromosome 19 open reading frame 66
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAMKMT calmodulin-lysine N-methyltransferase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD27 CD27 molecule
CD48 CD48 molecule
CD5 CD5 molecule
CHRM5 cholinergic receptor, muscarinic 5
CLCN2 chloride channel, voltage-sensitive 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRYAB crystallin, alpha B
DAGLA diacylglycerol lipase, alpha
DLK1 delta-like 1 homolog (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DOC2A double C2-like domains, alpha
DUSP13 dual specificity phosphatase 13
FAM184A family with sequence similarity 184, member A
FBXL6 F-box and leucine-rich repeat protein 6
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FGF4 fibroblast growth factor 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GJB1 gap junction protein, beta 1, 32kDa
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
HAO1 hydroxyacid oxidase (glycolate oxidase) 1
HIST1H3J histone cluster 1, H3j
HMGA2 high mobility group AT-hook 2
HOXA4 homeobox A4
HOXB1 homeobox B1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL10RA interleukin 10 receptor, alpha
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL22 interleukin 22
IRF8 interferon regulatory factor 8
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLHL26 kelch-like family member 26
KLHL3 kelch-like family member 3
KRT2 keratin 2, type II
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LEMD3 LEM domain containing 3
LOC100286895 cell division cycle 27 homolog pseudogene
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAPK3 mitogen-activated protein kinase 3
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MC5R melanocortin 5 receptor
MOB3B MOB kinase activator 3B
MYO1F myosin IF
NBAS neuroblastoma amplified sequence
NLRP2 NLR family, pyrin domain containing 2
NPR3 natriuretic peptide receptor 3
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PHOX2A paired-like homeobox 2a
PMEL premelanosome protein
PMEPA1 prostate transmembrane protein, androgen induced 1
PON3 paraoxonase 3
PQLC2 PQ loop repeat containing 2
PRKCE protein kinase C, epsilon
PRKG2 protein kinase, cGMP-dependent, type II
PRODH2 proline dehydrogenase (oxidase) 2
PRY PTPN13-like, Y-linked
RASL11B RAS-like, family 11, member B
REG1B regenerating islet-derived 1 beta
RHOH ras homolog family member H
SCIN scinderin
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SPON2 spondin 2, extracellular matrix protein
STARD5 StAR-related lipid transfer (START) domain containing 5
STARD8 StAR-related lipid transfer (START) domain containing 8
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNDIG1 synapse differentiation inducing 1
TAAR2 trace amine associated receptor 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCP10L t-complex 10-like
TEX15 testis expressed 15
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TOLLIP toll interacting protein
TP53I3 tumor protein p53 inducible protein 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSNAXIP1 translin-associated factor X interacting protein 1
ZBED1 zinc finger, BED-type containing 1
ZFR2 zinc finger RNA binding protein 2
ZNF580 zinc finger protein 580