genistein-5232 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the genistein-5232 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APP amyloid beta (A4) precursor protein
ARTN artemin
ASPH aspartate beta-hydroxylase
BAX BCL2-associated X protein
BMP1 bone morphogenetic protein 1
C21ORF2 chromosome 21 open reading frame 2
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAPN5 calpain 5
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK10 cyclin-dependent kinase 10
CFAP69 cilia and flagella associated protein 69
CLCN7 chloride channel, voltage-sensitive 7
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DAZAP1 DAZ associated protein 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DMTN dematin actin binding protein
DVL3 dishevelled segment polarity protein 3
EGR3 early growth response 3
EPPK1 epiplakin 1
FAM174B family with sequence similarity 174, member B
FHOD1 formin homology 2 domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GATAD2A GATA zinc finger domain containing 2A
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GOLGA8A golgin A8 family, member A
GPR3 G protein-coupled receptor 3
HAMP hepcidin antimicrobial peptide
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H4C histone cluster 1, H4c
HMGN5 high mobility group nucleosome binding domain 5
IDS iduronate 2-sulfatase
IGHM immunoglobulin heavy constant mu
INSR insulin receptor
IRF8 interferon regulatory factor 8
ITPK1 inositol-tetrakisphosphate 1-kinase
JAK3 Janus kinase 3
KAT6A K(lysine) acetyltransferase 6A
KHSRP KH-type splicing regulatory protein
KIF1C kinesin family member 1C
KRT15 keratin 15, type I
LAMP1 lysosomal-associated membrane protein 1
LIMK1 LIM domain kinase 1
LINC00597 long intergenic non-protein coding RNA 597
LPP LIM domain containing preferred translocation partner in lipoma
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAG18 NAG18 mRNA
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPHP4 nephronophthisis 4
NPM3 nucleophosmin/nucleoplasmin 3
PACS1 phosphofurin acidic cluster sorting protein 1
PBX2 pre-B-cell leukemia homeobox 2
PCDHA5 protocadherin alpha 5
PDIA4 protein disulfide isomerase family A, member 4
PELP1 proline, glutamate and leucine rich protein 1
PLAC4 placenta-specific 4
PLK3 polo-like kinase 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRB3 proline-rich protein BstNI subfamily 3
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGS10 regulator of G-protein signaling 10
RHBG Rh family, B glycoprotein (gene/pseudogene)
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFXN1 sideroflexin 1
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC35E2 solute carrier family 35, member E2
SLC38A7 solute carrier family 38, member 7
SMG7 SMG7 nonsense mediated mRNA decay factor
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SPAG8 sperm associated antigen 8
SRRM2 serine/arginine repetitive matrix 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TNPO2 transportin 2
TRAF4 TNF receptor-associated factor 4
TRIO trio Rho guanine nucleotide exchange factor
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
VIM vimentin
ZC3H7B zinc finger CCCH-type containing 7B
ZNF609 zinc finger protein 609
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP12 Rho GTPase activating protein 12
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BEX4 brain expressed, X-linked 4
BMP4 bone morphogenetic protein 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BSG basigin (Ok blood group)
C1ORF56 chromosome 1 open reading frame 56
C4ORF29 chromosome 4 open reading frame 29
CCDC121 coiled-coil domain containing 121
CCDC88C coiled-coil domain containing 88C
CFD complement factor D (adipsin)
COMMD10 COMM domain containing 10
CYB5R1 cytochrome b5 reductase 1
CYB5R4 cytochrome b5 reductase 4
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
ERMP1 endoplasmic reticulum metallopeptidase 1
EXOC5 exocyst complex component 5
F2R coagulation factor II (thrombin) receptor
FNTB farnesyltransferase, CAAX box, beta
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDE1 glycerophosphodiester phosphodiesterase 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLUD2 glutamate dehydrogenase 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GSTM4 glutathione S-transferase mu 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HELLS helicase, lymphoid-specific
HOXA4 homeobox A4
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDI2-AS1 IDI2 antisense RNA 1
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
INSIG2 insulin induced gene 2
IPP intracisternal A particle-promoted polypeptide
KIAA0894 KIAA0894 protein
KLHL12 kelch-like family member 12
KLHL28 kelch-like family member 28
LIG4 ligase IV, DNA, ATP-dependent
LOC730101 uncharacterized LOC730101
MBTD1 mbt domain containing 1
MOCS3 molybdenum cofactor synthesis 3
MPDU1 mannose-P-dolichol utilization defect 1
MPHOSPH8 M-phase phosphoprotein 8
NMD3 NMD3 ribosome export adaptor
OSMR oncostatin M receptor
PARD6A par-6 family cell polarity regulator alpha
PHC1 polyhomeotic homolog 1 (Drosophila)
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB8B RAB8B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAI suppressor of cancer cell invasion
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A40 solute carrier family 25, member 40
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SPRYD7 SPRY domain containing 7
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STK19 serine/threonine kinase 19
STRN striatin, calmodulin binding protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYTL2 synaptotagmin-like 2
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TMEM230 transmembrane protein 230
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSPAN1 tetraspanin 1
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YAF2 YY1 associated factor 2
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF286A zinc finger protein 286A
ZNF557 zinc finger protein 557
ZNF586 zinc finger protein 586
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF91 zinc finger protein 91