genistein-5595 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the genistein-5595 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AKAP1 A kinase (PRKA) anchor protein 1
ALS2CL ALS2 C-terminal like
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATXN7L1 ataxin 7-like 1
BIN1 bridging integrator 1
BTNL3 butyrophilin-like 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CA5B carbonic anhydrase VB, mitochondrial
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASP10 caspase 10, apoptosis-related cysteine peptidase
CELF2 CUGBP, Elav-like family member 2
CEP250 centrosomal protein 250kDa
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLEC4E C-type lectin domain family 4, member E
CNN1 calponin 1, basic, smooth muscle
CNTNAP2 contactin associated protein-like 2
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNASE1L3 deoxyribonuclease I-like 3
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYSF dysferlin
EGR3 early growth response 3
EZR ezrin
FAM188A family with sequence similarity 188, member A
FBXO21 F-box protein 21
FGF3 fibroblast growth factor 3
FLJ11292
FRK fyn-related Src family tyrosine kinase
GREB1 growth regulation by estrogen in breast cancer 1
GREB1L growth regulation by estrogen in breast cancer-like
GSPT2 G1 to S phase transition 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H2BN histone cluster 1, H2bn
HIST1H4C histone cluster 1, H4c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HUS1 HUS1 checkpoint homolog (S. pombe)
IL24 interleukin 24
ING2 inhibitor of growth family, member 2
IRF4 interferon regulatory factor 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD17 potassium channel tetramerization domain containing 17
LIF leukemia inhibitory factor
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMTK1 lemur tail kinase 1
MAOA monoamine oxidase A
MAPK10 mitogen-activated protein kinase 10
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NCKIPSD NCK interacting protein with SH3 domain
NDOR1 NADPH dependent diflavin oxidoreductase 1
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NELL2 NEL-like 2 (chicken)
NOVA2 neuro-oncological ventral antigen 2
NPC1 Niemann-Pick disease, type C1
NPY1R neuropeptide Y receptor Y1
NTM neurotrimin
NXPH3 neurexophilin 3
PCDHB12 protocadherin beta 12
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
POPDC3 popeye domain containing 3
PRKCI protein kinase C, iota
PTPN11 protein tyrosine phosphatase, non-receptor type 11
R3HDM1 R3H domain containing 1
RASAL2 RAS protein activator like 2
RIPK2 receptor-interacting serine-threonine kinase 2
RPLP2 ribosomal protein, large, P2
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC24D SEC24 family member D
SGK1 serum/glucocorticoid regulated kinase 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPP1 secreted phosphoprotein 1
SRSF5 serine/arginine-rich splicing factor 5
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAAR5 trace amine associated receptor 5
TAS2R1 taste receptor, type 2, member 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCP11L1 t-complex 11, testis-specific-like 1
TGFA transforming growth factor, alpha
TMEM38B transmembrane protein 38B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP63 tumor protein p63
TRBC1 T cell receptor beta constant 1
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
USP34 ubiquitin specific peptidase 34
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WIPI1 WD repeat domain, phosphoinositide interacting 1
YY2 YY2 transcription factor
ZNF235 zinc finger protein 235
ZNF236 zinc finger protein 236
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABLIM3 actin binding LIM protein family, member 3
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ARC activity-regulated cytoskeleton-associated protein
ARRB1 arrestin, beta 1
ATP10D ATPase, class V, type 10D
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
CA5BP1 carbonic anhydrase VB pseudogene 1
CD1A CD1a molecule
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CEP112 centrosomal protein 112kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLSPN claspin
CORO7 coronin 7
CRLF1 cytokine receptor-like factor 1
CRYGC crystallin, gamma C
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
DUSP13 dual specificity phosphatase 13
DUSP2 dual specificity phosphatase 2
EGFL7 EGF-like-domain, multiple 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EVPL envoplakin
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLI3 GLI family zinc finger 3
HCAR3 hydroxycarboxylic acid receptor 3
HCRTR2 hypocretin (orexin) receptor 2
HIST1H2BO histone cluster 1, H2bo
HIST1H4A histone cluster 1, H4a
HOXA4 homeobox A4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT54 intraflagellar transport 54
IQCC IQ motif containing C
IRF1 interferon regulatory factor 1
KREMEN2 kringle containing transmembrane protein 2
KRT15 keratin 15, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC157562 uncharacterized LOC157562
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC15 leucine rich repeat containing 15
LRRC37A3 leucine rich repeat containing 37, member A3
LRRTM2 leucine rich repeat transmembrane neuronal 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MANBA mannosidase, beta A, lysosomal
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL41 mitochondrial ribosomal protein L41
MSI1 musashi RNA-binding protein 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NOD2 nucleotide-binding oligomerization domain containing 2
NPFFR1 neuropeptide FF receptor 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NYNRIN NYN domain and retroviral integrase containing
ONECUT2 one cut homeobox 2
OVOL1 ovo-like zinc finger 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PKD2L2 polycystic kidney disease 2-like 2
PLA2G3 phospholipase A2, group III
PODNL1 podocan-like 1
PROL1 proline rich, lacrimal 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHOBTB2 Rho-related BTB domain containing 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF122 ring finger protein 122
S100A9 S100 calcium binding protein A9
SECTM1 secreted and transmembrane 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC12A8 solute carrier family 12, member 8
SLC16A4 solute carrier family 16, member 4
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLMO1 slowmo homolog 1 (Drosophila)
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPAG4 sperm associated antigen 4
SPRY2 sprouty homolog 2 (Drosophila)
SSTR4 somatostatin receptor 4
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
THBS3 thrombospondin 3
TMEM121 transmembrane protein 121
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
WFDC2 WAP four-disulfide core domain 2
ZFHX2 zinc finger homeobox 2
ZNF408 zinc finger protein 408
ZNF747 zinc finger protein 747