genistein-6194 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the genistein-6194 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABHD2 abhydrolase domain containing 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALDOB aldolase B, fructose-bisphosphate
ANK2 ankyrin 2, neuronal
APOL2 apolipoprotein L, 2
AQP2 aquaporin 2 (collecting duct)
AREG amphiregulin
ARG1 arginase 1
ARHGAP44 Rho GTPase activating protein 44
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUD31 BUD31 homolog (S. cerevisiae)
C5ORF45 chromosome 5 open reading frame 45
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCL27 chemokine (C-C motif) ligand 27
CHN2 chimerin 2
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
CPA2 carboxypeptidase A2 (pancreatic)
CREM cAMP responsive element modulator
CSPG4 chondroitin sulfate proteoglycan 4
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DMC1 DNA meiotic recombinase 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DPEP2 dipeptidase 2
DST dystonin
DUSP26 dual specificity phosphatase 26 (putative)
DVL2 dishevelled segment polarity protein 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FDXR ferredoxin reductase
FGD1 FYVE, RhoGEF and PH domain containing 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
HBP1 HMG-box transcription factor 1
HPCAL4 hippocalcin like 4
ICOSLG inducible T-cell co-stimulator ligand
IFNA7 interferon, alpha 7
IGL immunoglobulin lambda locus
JPH3 junctophilin 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0513 KIAA0513
KLHL1 kelch-like family member 1
KYNU kynureninase
LAMP1 lysosomal-associated membrane protein 1
LEPR leptin receptor
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LMF1 lipase maturation factor 1
LMTK1 lemur tail kinase 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBNL2 muscleblind-like splicing regulator 2
MOBP myelin-associated oligodendrocyte basic protein
MST1 macrophage stimulating 1
NNMT nicotinamide N-methyltransferase
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRCAM neuronal cell adhesion molecule
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAX8 paired box 8
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM4 PDZ and LIM domain 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RASAL2 RAS protein activator like 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBBP4 retinoblastoma binding protein 4
RBMS3 RNA binding motif, single stranded interacting protein 3
REC8 REC8 meiotic recombination protein
REG1B regenerating islet-derived 1 beta
RGS4 regulator of G-protein signaling 4
SCN5A sodium channel, voltage gated, type V alpha subunit
SEZ6L seizure related 6 homolog (mouse)-like
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC26A10 solute carrier family 26, member 10
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPDEF SAM pointed domain containing ETS transcription factor
TCF3 transcription factor 3
TESPA1 thymocyte expressed, positive selection associated 1
THBS1 thrombospondin 1
TK2 thymidine kinase 2, mitochondrial
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRH thyrotropin-releasing hormone
USH2A Usher syndrome 2A (autosomal recessive, mild)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VSNL1 visinin-like 1
WFDC2 WAP four-disulfide core domain 2
ZC3H13 zinc finger CCCH-type containing 13
ZER1 zyg-11 related, cell cycle regulator
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AMT aminomethyltransferase
ANXA3 annexin A3
APOL6 apolipoprotein L, 6
ARMC6 armadillo repeat containing 6
ATAD3A ATPase family, AAA domain containing 3A
BAHCC1 BAH domain and coiled-coil containing 1
C12ORF29 chromosome 12 open reading frame 29
C22ORF29 chromosome 22 open reading frame 29
CCNJ cyclin J
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD1C CD1c molecule
CDK20 cyclin-dependent kinase 20
CDKL3 cyclin-dependent kinase-like 3
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COL15A1 collagen, type XV, alpha 1
CTAGE9 CTAGE family, member 9
CUX2 cut-like homeobox 2
DDN dendrin
DEAF1 DEAF1 transcription factor
DKK2 dickkopf WNT signaling pathway inhibitor 2
DVL1 dishevelled segment polarity protein 1
DYSF dysferlin
F8 coagulation factor VIII, procoagulant component
FADS2 fatty acid desaturase 2
FAM86B1 family with sequence similarity 86, member B1
FJX1 four jointed box 1 (Drosophila)
FMO4 flavin containing monooxygenase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPATCH2L G patch domain containing 2-like
GPR35 G protein-coupled receptor 35
HIST1H2AJ histone cluster 1, H2aj
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IMPAD1 inositol monophosphatase domain containing 1
INHBE inhibin, beta E
INO80D INO80 complex subunit D
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIF1B kinesin family member 1B
KLF11 Kruppel-like factor 11
KLHL26 kelch-like family member 26
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LOC100286895 cell division cycle 27 homolog pseudogene
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPPR3 lipid phosphate phosphatase-related protein type 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP5 low density lipoprotein receptor-related protein 5
MAGEB2 melanoma antigen family B2
MBNL3 muscleblind-like splicing regulator 3
MED9 mediator complex subunit 9
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
MOCOS molybdenum cofactor sulfurase
MOSPD3 motile sperm domain containing 3
MTERF1 mitochondrial transcription termination factor 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PARP16 poly (ADP-ribose) polymerase family, member 16
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
PTPRS protein tyrosine phosphatase, receptor type, S
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SOX12 SRY (sex determining region Y)-box 12
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCEA2 transcription elongation factor A (SII), 2
TERT telomerase reverse transcriptase
TMEM254 transmembrane protein 254
TRAIP TRAF interacting protein
TRIM58 tripartite motif containing 58
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWISTNB TWIST neighbor
TXLNG taxilin gamma
WDR3 WD repeat domain 3
WDR43 WD repeat domain 43
WWC2 WW and C2 domain containing 2
ZHX2 zinc fingers and homeoboxes 2
ZNF232 zinc finger protein 232
ZNF493 zinc finger protein 493
ZNF667 zinc finger protein 667
ZNF76 zinc finger protein 76
ZNRD1-AS1 ZNRD1 antisense RNA 1