genistein-638 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the genistein-638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACOT11 acyl-CoA thioesterase 11
ADD2 adducin 2 (beta)
AGXT alanine-glyoxylate aminotransferase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARHGAP19 Rho GTPase activating protein 19
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCHCR1 coiled-coil alpha-helical rod protein 1
CD34 CD34 molecule
CIAO1 cytosolic iron-sulfur assembly component 1
CYB5R3 cytochrome b5 reductase 3
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DENND3 DENN/MADD domain containing 3
DIEXF digestive organ expansion factor homolog (zebrafish)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DST dystonin
E2F3 E2F transcription factor 3
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ERP44 endoplasmic reticulum protein 44
EVPL envoplakin
FAM114A2 family with sequence similarity 114, member A2
FAM46C family with sequence similarity 46, member C
FHL1 four and a half LIM domains 1
FSCN3 fascin actin-bundling protein 3, testicular
GLS2 glutaminase 2 (liver, mitochondrial)
GM2A GM2 ganglioside activator
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GP2 glycoprotein 2 (zymogen granule membrane)
GPATCH4 G patch domain containing 4
GSTCD glutathione S-transferase, C-terminal domain containing
HIPK2 homeodomain interacting protein kinase 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IRF7 interferon regulatory factor 7
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JADE3 jade family PHD finger 3
JRKL JRK-like
KLF15 Kruppel-like factor 15
KLHL35 kelch-like family member 35
KLK5 kallikrein-related peptidase 5
KPNB1 karyopherin (importin) beta 1
LARS leucyl-tRNA synthetase
LUZP1 leucine zipper protein 1
LZTFL1 leucine zipper transcription factor-like 1
MEFV Mediterranean fever
METAP2 methionyl aminopeptidase 2
MTERF4 mitochondrial transcription termination factor 4
MTMR2 myotubularin related protein 2
MYL10 myosin, light chain 10, regulatory
NGLY1 N-glycanase 1
NLRX1 NLR family member X1
NPTX1 neuronal pentraxin I
NPTXR neuronal pentraxin receptor
NXPH3 neurexophilin 3
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR6A2 olfactory receptor, family 6, subfamily A, member 2
OSTM1 osteopetrosis associated transmembrane protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLAU plasminogen activator, urokinase
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PRDM14 PR domain containing 14
PROL1 proline rich, lacrimal 1
RBM5 RNA binding motif protein 5
RDH8 retinol dehydrogenase 8 (all-trans)
RGS11 regulator of G-protein signaling 11
RPL37A ribosomal protein L37a
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RRBP1 ribosome binding protein 1
RRH retinal pigment epithelium-derived rhodopsin homolog
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEC24D SEC24 family member D
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SND1-IT1 SND1 intronic transcript 1
SRSF11 serine/arginine-rich splicing factor 11
SYT12 synaptotagmin XII
SYT2 synaptotagmin II
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAS2R1 taste receptor, type 2, member 1
TGM2 transglutaminase 2
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM51 transmembrane protein 51
TP53I11 tumor protein p53 inducible protein 11
TPT1 tumor protein, translationally-controlled 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TULP2 tubby like protein 2
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
VAC14 Vac14 homolog (S. cerevisiae)
WDR48 WD repeat domain 48
WIPF1 WAS/WASL interacting protein family, member 1
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF287 zinc finger protein 287
ZNF318 zinc finger protein 318
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ACBD4 acyl-CoA binding domain containing 4
ADAM23 ADAM metallopeptidase domain 23
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARPIN actin-related protein 2/3 complex inhibitor
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BAHCC1 BAH domain and coiled-coil containing 1
BIK BCL2-interacting killer (apoptosis-inducing)
C2ORF54 chromosome 2 open reading frame 54
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CA9 carbonic anhydrase IX
CAV3 caveolin 3
CBX2 chromobox homolog 2
CBX8 chromobox homolog 8
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDR2L cerebellar degeneration-related protein 2-like
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COPZ2 coatomer protein complex, subunit zeta 2
COQ4 coenzyme Q4
CORO7 coronin 7
CRYAA crystallin, alpha A
CTC1 CTS telomere maintenance complex component 1
DGAT1 diacylglycerol O-acyltransferase 1
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DRP2 dystrophin related protein 2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECM1 extracellular matrix protein 1
EFNA1 ephrin-A1
EPHA4 EPH receptor A4
ERN2 endoplasmic reticulum to nucleus signaling 2
FGL1 fibrinogen-like 1
FRS2 fibroblast growth factor receptor substrate 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GINS4 GINS complex subunit 4 (Sld5 homolog)
GJA5 gap junction protein, alpha 5, 40kDa
GJB1 gap junction protein, beta 1, 32kDa
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR21 G protein-coupled receptor 21
GSTT1 glutathione S-transferase theta 1
GUSBP3 glucuronidase, beta pseudogene 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IL12RB1 interleukin 12 receptor, beta 1
IL19 interleukin 19
KCTD17 potassium channel tetramerization domain containing 17
KDM8 lysine (K)-specific demethylase 8
KLHL28 kelch-like family member 28
MAPK10 mitogen-activated protein kinase 10
MARC1 mitochondrial amidoxime reducing component 1
MFAP2 microfibrillar-associated protein 2
MFSD12 major facilitator superfamily domain containing 12
MPPED1 metallophosphoesterase domain containing 1
MTG1 mitochondrial ribosome-associated GTPase 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OCLN occludin
OMG oligodendrocyte myelin glycoprotein
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PAX1 paired box 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PLA2G3 phospholipase A2, group III
PMEL premelanosome protein
POGLUT1 protein O-glucosyltransferase 1
POU5F1B POU class 5 homeobox 1B
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB4B RAB4B, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RBM47 RNA binding motif protein 47
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF187 ring finger protein 187
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
S100A4 S100 calcium binding protein A4
SGCE sarcoglycan, epsilon
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SRPK3 SRSF protein kinase 3
STARD8 StAR-related lipid transfer (START) domain containing 8
SUSD4 sushi domain containing 4
TAS2R4 taste receptor, type 2, member 4
TCEA2 transcription elongation factor A (SII), 2
TIMP2 TIMP metallopeptidase inhibitor 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM209 transmembrane protein 209
TRIM8 tripartite motif containing 8
UNC93B1 unc-93 homolog B1 (C. elegans)
ZFHX2 zinc finger homeobox 2
ZNF446 zinc finger protein 446