genistein-6952 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the genistein-6952 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
ANGPT4 angiopoietin 4
ANKRD40 ankyrin repeat domain 40
AREG amphiregulin
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ASTN2 astrotactin 2
ATG3 autophagy related 3
BLVRA biliverdin reductase A
BTD biotinidase
C14ORF93 chromosome 14 open reading frame 93
C18ORF25 chromosome 18 open reading frame 25
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACYBP calcyclin binding protein
CD82 CD82 molecule
CEP104 centrosomal protein 104kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CRTC1 CREB regulated transcription coactivator 1
CTAGE5 CTAGE family, member 5
CTBS chitobiase, di-N-acetyl-
CUZD1 CUB and zona pellucida-like domains 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DENND5B DENN/MADD domain containing 5B
DMPK dystrophia myotonica-protein kinase
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGR3 early growth response 3
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FGF12 fibroblast growth factor 12
FN1 fibronectin 1
FRMPD1 FERM and PDZ domain containing 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GOSR2 golgi SNAP receptor complex member 2
GREB1 growth regulation by estrogen in breast cancer 1
HAUS6 HAUS augmin-like complex, subunit 6
HYI hydroxypyruvate isomerase (putative)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
JUN jun proto-oncogene
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM4B lysine (K)-specific demethylase 4B
KRT13 keratin 13, type I
KSR1 kinase suppressor of ras 1
LEFTY2 left-right determination factor 2
LTC4S leukotriene C4 synthase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MRPL44 mitochondrial ribosomal protein L44
NAV2 neuron navigator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NGLY1 N-glycanase 1
NUMA1 nuclear mitotic apparatus protein 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
OGFR opioid growth factor receptor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PDE4DIP phosphodiesterase 4D interacting protein
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLSCR4 phospholipid scramblase 4
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTBP3 polypyrimidine tract binding protein 3
PTPRF protein tyrosine phosphatase, receptor type, F
RARA retinoic acid receptor, alpha
RGS10 regulator of G-protein signaling 10
RP2 retinitis pigmentosa 2 (X-linked recessive)
S100A11 S100 calcium binding protein A11
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SENP6 SUMO1/sentrin specific peptidase 6
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIK3 SIK family kinase 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A17 solute carrier family 22, member 17
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUGP2 SURP and G patch domain containing 2
SYNM synemin, intermediate filament protein
TECTA tectorin alpha
TJAP1 tight junction associated protein 1 (peripheral)
TK2 thymidine kinase 2, mitochondrial
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
ULBP2 UL16 binding protein 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WSCD1 WSC domain containing 1
XK X-linked Kx blood group
ZHX3 zinc fingers and homeoboxes 3
ZNF318 zinc finger protein 318
ZNF37BP zinc finger protein 37B, pseudogene
ZNF571 zinc finger protein 571

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ANKHD1 ankyrin repeat and KH domain containing 1
ANXA1 annexin A1
ARMC7 armadillo repeat containing 7
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCORL1 BCL6 corepressor-like 1
BIN3 bridging integrator 3
C11ORF68 chromosome 11 open reading frame 68
C16ORF59 chromosome 16 open reading frame 59
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
CCP110 centriolar coiled coil protein 110kDa
CDKL3 cyclin-dependent kinase-like 3
CDKN2AIP CDKN2A interacting protein
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
COL9A2 collagen, type IX, alpha 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRY2 cryptochrome circadian clock 2
CTSK cathepsin K
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
EFNA1 ephrin-A1
EIF5A2 eukaryotic translation initiation factor 5A2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EYA2 EYA transcriptional coactivator and phosphatase 2
FANCE Fanconi anemia, complementation group E
FASTKD5 FAST kinase domains 5
FBRS fibrosin
GADD45G growth arrest and DNA-damage-inducible, gamma
GATA4 GATA binding protein 4
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HINFP histone H4 transcription factor
HIST1H2BC histone cluster 1, H2bc
HIST1H2BI histone cluster 1, H2bi
HOXC13 homeobox C13
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL4R interleukin 4 receptor
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KLF3 Kruppel-like factor 3 (basic)
LHFPL2 lipoma HMGIC fusion partner-like 2
LIN7B lin-7 homolog B (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LOC257152 uncharacterized LOC257152
LRRC20 leucine rich repeat containing 20
LYPD1 LY6/PLAUR domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
METTL16 methyltransferase like 16
METTL21B methyltransferase like 21B
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL52 mitochondrial ribosomal protein L52
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUAK1 NUAK family, SNF1-like kinase, 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PANK4 pantothenate kinase 4
PANX1 pannexin 1
PARPBP PARP1 binding protein
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLL polymerase (DNA directed), lambda
PPAP2C phosphatidic acid phosphatase type 2C
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PROS1 protein S (alpha)
PTPRU protein tyrosine phosphatase, receptor type, U
RAB23 RAB23, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SAMD9 sterile alpha motif domain containing 9
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
STAG3 stromal antigen 3
STARD5 StAR-related lipid transfer (START) domain containing 5
TCTN2 tectonic family member 2
TH tyrosine hydroxylase
TMC5 transmembrane channel-like 5
TMEM2 transmembrane protein 2
TMEM254 transmembrane protein 254
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM45 tripartite motif containing 45
TUBGCP5 tubulin, gamma complex associated protein 5
VASH2 vasohibin 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB48 zinc finger and BTB domain containing 48
ZNF226 zinc finger protein 226
ZNF276 zinc finger protein 276
ZNF408 zinc finger protein 408
ZNF675 zinc finger protein 675