genistein-703 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the genistein-703 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADSL adenylosuccinate lyase
AGGF1 angiogenic factor with G patch and FHA domains 1
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AHCYL2 adenosylhomocysteinase-like 2
ANXA2P3 annexin A2 pseudogene 3
AQP3 aquaporin 3 (Gill blood group)
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BEGAIN brain-enriched guanylate kinase-associated
C6ORF47 chromosome 6 open reading frame 47
CALD1 caldesmon 1
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CDT1 chromatin licensing and DNA replication factor 1
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CTNNBIP1 catenin, beta interacting protein 1
DAXX death-domain associated protein
DHFR dihydrofolate reductase
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DPYSL3 dihydropyrimidinase-like 3
DXO decapping exoribonuclease
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPOR erythropoietin receptor
ESRP2 epithelial splicing regulatory protein 2
FAM188A family with sequence similarity 188, member A
FGF4 fibroblast growth factor 4
FNDC3A fibronectin type III domain containing 3A
GMDS GDP-mannose 4,6-dehydratase
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSE1 Gse1 coiled-coil protein
H2AFY2 H2A histone family, member Y2
HCG26 HLA complex group 26 (non-protein coding)
HEATR1 HEAT repeat containing 1
HIRIP3 HIRA interacting protein 3
HMOX2 heme oxygenase 2
IL1RN interleukin 1 receptor antagonist
INTS12 integrator complex subunit 12
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIAA0195 KIAA0195
KIAA1467 KIAA1467
KLHDC10 kelch domain containing 10
KRT32 keratin 32, type I
LARP1 La ribonucleoprotein domain family, member 1
LDHC lactate dehydrogenase C
MANBA mannosidase, beta A, lysosomal
MOB3B MOB kinase activator 3B
MYH10 myosin, heavy chain 10, non-muscle
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NMB neuromedin B
NOV nephroblastoma overexpressed
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTAN1 N-terminal asparagine amidase
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUCB2 nucleobindin 2
OSBPL3 oxysterol binding protein-like 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCIF1 PDX1 C-terminal inhibiting factor 1
PDCD2 programmed cell death 2
PGAP2 post-GPI attachment to proteins 2
PGK1 phosphoglycerate kinase 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLAC1 placenta-specific 1
PLAUR plasminogen activator, urokinase receptor
PNRC1 proline-rich nuclear receptor coactivator 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAD51AP1 RAD51 associated protein 1
RBBP6 retinoblastoma binding protein 6
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SBF1 SET binding factor 1
SIK3 SIK family kinase 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SOCS5 suppressor of cytokine signaling 5
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STAB2 stabilin 2
STAC SH3 and cysteine rich domain
STK19 serine/threonine kinase 19
STX2 syntaxin 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D31 TBC1 domain family, member 31
TDG thymine-DNA glycosylase
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAK2 trafficking protein, kinesin binding 2
TRIM10 tripartite motif containing 10
USP6 ubiquitin specific peptidase 6
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR11 WD repeat domain 11
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD4 acyl-CoA binding domain containing 4
ADAP2 ArfGAP with dual PH domains 2
ADTRP androgen-dependent TFPI-regulating protein
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMT aminomethyltransferase
ANKRD36B ankyrin repeat domain 36B
ANKRD40 ankyrin repeat domain 40
ASCC2 activating signal cointegrator 1 complex subunit 2
BANP BTG3 associated nuclear protein
CA11 carbonic anhydrase XI
CA7 carbonic anhydrase VII
CCNA1 cyclin A1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD1A CD1a molecule
CFAP74 cilia and flagella associated protein 74
CNTD2 cyclin N-terminal domain containing 2
CNTNAP1 contactin associated protein 1
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DOLK dolichol kinase
EAPP E2F-associated phosphoprotein
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPS8L3 EPS8-like 3
ETV7 ets variant 7
FAM155B family with sequence similarity 155, member B
FBXL2 F-box and leucine-rich repeat protein 2
FBXW4 F-box and WD repeat domain containing 4
FRS3 fibroblast growth factor receptor substrate 3
FSCN3 fascin actin-bundling protein 3, testicular
G6PC2 glucose-6-phosphatase, catalytic, 2
GAST gastrin
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GBX2 gastrulation brain homeobox 2
GPR21 G protein-coupled receptor 21
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HAS2 hyaluronan synthase 2
HELLS helicase, lymphoid-specific
HIST1H2BC histone cluster 1, H2bc
HIST3H2A histone cluster 3, H2a
HMX1 H6 family homeobox 1
HOXC11 homeobox C11
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
KIFC1 kinesin family member C1
KLF15 Kruppel-like factor 15
KLHL21 kelch-like family member 21
KLHL3 kelch-like family member 3
LHX6 LIM homeobox 6
LRRC37A3 leucine rich repeat containing 37, member A3
MAP7D1 MAP7 domain containing 1
MAPK10 mitogen-activated protein kinase 10
MAPKBP1 mitogen-activated protein kinase binding protein 1
MARC1 mitochondrial amidoxime reducing component 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NAP1L4 nucleosome assembly protein 1-like 4
NARF nuclear prelamin A recognition factor
NELL2 NEL-like 2 (chicken)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPDC1 neural proliferation, differentiation and control, 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NXN nucleoredoxin
OMG oligodendrocyte myelin glycoprotein
OSBPL11 oxysterol binding protein-like 11
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PANK4 pantothenate kinase 4
PAQR4 progestin and adipoQ receptor family member IV
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGR polymeric immunoglobulin receptor
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
RAD54L RAD54-like (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBBP5 retinoblastoma binding protein 5
RBM4B RNA binding motif protein 4B
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPAP2 RNA polymerase II associated protein 2
RSF1 remodeling and spacing factor 1
SCNM1 sodium channel modifier 1
SDC3 syndecan 3
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC12A9 solute carrier family 12, member 9
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATS2 spermatogenesis associated, serine-rich 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
UBOX5 U-box domain containing 5
UNC13B unc-13 homolog B (C. elegans)
VASP vasodilator-stimulated phosphoprotein
VIPR1 vasoactive intestinal peptide receptor 1
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC6 zinc finger, DHHC-type containing 6
ZFP36 ZFP36 ring finger protein