genistein Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description 7-Hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties. (Chemical Entities of Biological Interest Ontology, CHEBI_28088)
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Genes

74 genes co-occuring with the biological term genistein in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AKT1 v-akt murine thymoma viral oncogene homolog 1
APP amyloid beta (A4) precursor protein
AR androgen receptor
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATM ATM serine/threonine kinase
BIRC7 baculoviral IAP repeat containing 7
BMP2 bone morphogenetic protein 2
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CREB1 cAMP responsive element binding protein 1
CTGF connective tissue growth factor
CXADR coxsackie virus and adenovirus receptor
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGF epidermal growth factor
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GCLC glutamate-cysteine ligase, catalytic subunit
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
IGF1R insulin-like growth factor 1 receptor
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL10 interleukin 10
JUN jun proto-oncogene
KIF20A kinesin family member 20A
KISS1 KiSS-1 metastasis-suppressor
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MGMT O-6-methylguanine-DNA methyltransferase
MIR1260B microRNA 1260b
NFE2L2 nuclear factor, erythroid 2-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
PCNA proliferating cell nuclear antigen
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARA retinoic acid receptor, alpha
RUNX2 runt-related transcription factor 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFRP1 secreted frizzled-related protein 1
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SRF serum response factor (c-fos serum response element-binding transcription factor)
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TTR transthyretin
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
VEGFA vascular endothelial growth factor A