genotoxic Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

96 proteins co-occuring with the biological term genotoxic in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
AKT1 v-akt murine thymoma viral oncogene homolog 1
APLF aprataxin and PNKP like factor
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
BAD BCL2-associated agonist of cell death
BARD1 BRCA1 associated RING domain 1
BCL2L1 BCL2-like 1
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC6 coiled-coil domain containing 6
CCND1 cyclin D1
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM129A family with sequence similarity 129, member A
FANCM Fanconi anemia, complementation group M
FBXO31 F-box protein 31
FOXO1 forkhead box O1
GTF2I general transcription factor IIi
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
HIST1H3A histone cluster 1, H3a
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
ING1 inhibitor of growth family, member 1
JUN jun proto-oncogene
KMT2A lysine (K)-specific methyltransferase 2A
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYH9 myosin, heavy chain 9, non-muscle
MYOD1 myogenic differentiation 1
NBN nibrin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PARN poly(A)-specific ribonuclease
PIDD1 p53-induced death domain protein 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PLSCR1 phospholipid scramblase 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCE protein kinase C, epsilon
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
RAD17 RAD17 homolog (S. pombe)
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RPA2 replication protein A2, 32kDa
RPS3 ribosomal protein S3
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRM2 ribonucleotide reductase M2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SMAD1 SMAD family member 1
SMC1A structural maintenance of chromosomes 1A
SOD2 superoxide dismutase 2, mitochondrial
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TDP1 tyrosyl-DNA phosphodiesterase 1
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TRIM28 tripartite motif containing 28
TWIST1 twist family bHLH transcription factor 1
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VIM vimentin
YAP1 Yes-associated protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZNHIT1 zinc finger, HIT-type containing 1