gentamicin-2082 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the gentamicin-2082 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATAD2B ATPase family, AAA domain containing 2B
BAX BCL2-associated X protein
BCL9 B-cell CLL/lymphoma 9
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
C1ORF54 chromosome 1 open reading frame 54
CACFD1 calcium channel flower domain containing 1
CACYBP calcyclin binding protein
CAMTA2 calmodulin binding transcription activator 2
CCDC106 coiled-coil domain containing 106
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DSC2 desmocollin 2
DTX2 deltex 2, E3 ubiquitin ligase
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPS8L1 EPS8-like 1
FAM174B family with sequence similarity 174, member B
FOXO1 forkhead box O1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GPR4 G protein-coupled receptor 4
HABP4 hyaluronan binding protein 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCTD17 potassium channel tetramerization domain containing 17
KIAA0930 KIAA0930
KIAA1456 KIAA1456
KIAA1644 KIAA1644
KIDINS220 kinase D-interacting substrate, 220kDa
KIF1C kinesin family member 1C
KRT16 keratin 16, type I
LAMP1 lysosomal-associated membrane protein 1
LOC730101 uncharacterized LOC730101
LPAR4 lysophosphatidic acid receptor 4
LRRN2 leucine rich repeat neuronal 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK7 mitogen-activated protein kinase 7
MAPT microtubule-associated protein tau
MIIP migration and invasion inhibitory protein
MLX MLX, MAX dimerization protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPI mannose phosphate isomerase
MRPS34 mitochondrial ribosomal protein S34
MTSS1L metastasis suppressor 1-like
MYRF myelin regulatory factor
N4BP2L2 NEDD4 binding protein 2-like 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPBL Nipped-B homolog (Drosophila)
NMT2 N-myristoyltransferase 2
NPM3 nucleophosmin/nucleoplasmin 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PBX2 pre-B-cell leukemia homeobox 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PIDD1 p53-induced death domain protein 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPCS phosphopantothenoylcysteine synthetase
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTGES prostaglandin E synthase
PVR poliovirus receptor
RAB5B RAB5B, member RAS oncogene family
RARG retinoic acid receptor, gamma
RBPMS RNA binding protein with multiple splicing
RPS9 ribosomal protein S9
SFTPB surfactant protein B
SLC25A44 solute carrier family 25, member 44
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPATS2L spermatogenesis associated, serine-rich 2-like
SQSTM1 sequestosome 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SUGP1 SURP and G patch domain containing 1
SYT17 synaptotagmin XVII
TBCD tubulin folding cofactor D
TLN2 talin 2
TMEM120B transmembrane protein 120B
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN9 tetraspanin 9
TUBA3C tubulin, alpha 3c
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF358 zinc finger protein 358
ZNF41 zinc finger protein 41
ZNF710 zinc finger protein 710
ZNF79 zinc finger protein 79
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
ACAD8 acyl-CoA dehydrogenase family, member 8
ACVR2A activin A receptor, type IIA
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ANKRD40 ankyrin repeat domain 40
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARL14 ADP-ribosylation factor-like 14
AZI2 5-azacytidine induced 2
BAG4 BCL2-associated athanogene 4
C19ORF40 chromosome 19 open reading frame 40
CA11 carbonic anhydrase XI
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNF cyclin F
CCNT1 cyclin T1
CDK3 cyclin-dependent kinase 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CNGB3 cyclic nucleotide gated channel beta 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL2 chemokine (C-X-C motif) ligand 2
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DCAF17 DDB1 and CUL4 associated factor 17
EGF epidermal growth factor
EPN3 epsin 3
EXOC5 exocyst complex component 5
FA2H fatty acid 2-hydroxylase
FBRS fibrosin
FCHSD2 FCH and double SH3 domains 2
GLT8D2 glycosyltransferase 8 domain containing 2
GPR1 G protein-coupled receptor 1
HDAC7 histone deacetylase 7
HINFP histone H4 transcription factor
HMHA1 histocompatibility (minor) HA-1
IFT22 intraflagellar transport 22
IGFLR1 IGF-like family receptor 1
JMJD4 jumonji domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KIAA0355 KIAA0355
KIF3A kinesin family member 3A
KLHL12 kelch-like family member 12
LIG4 ligase IV, DNA, ATP-dependent
LRRC8E leucine rich repeat containing 8 family, member E
MAGEA6 melanoma antigen family A6
NOD1 nucleotide-binding oligomerization domain containing 1
NOL12 nucleolar protein 12
NT5M 5',3'-nucleotidase, mitochondrial
OSMR oncostatin M receptor
OXR1 oxidation resistance 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPCDC phosphopantothenoylcysteine decarboxylase
PRICKLE3 prickle homolog 3 (Drosophila)
RARS arginyl-tRNA synthetase
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RUNX3 runt-related transcription factor 3
SCAMP5 secretory carrier membrane protein 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SDC3 syndecan 3
SEPP1 selenoprotein P, plasma, 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SP140L SP140 nuclear body protein-like
SPATA2L spermatogenesis associated 2-like
SPATA7 spermatogenesis associated 7
SYNJ2BP synaptojanin 2 binding protein
SYTL2 synaptotagmin-like 2
TBC1D19 TBC1 domain family, member 19
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMC5 transmembrane channel-like 5
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TMOD3 tropomodulin 3 (ubiquitous)
TMSB15A thymosin beta 15a
TNS2 tensin 2
TRIM21 tripartite motif containing 21
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTPAL tocopherol (alpha) transfer protein-like
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
VEGFB vascular endothelial growth factor B
ZMAT3 zinc finger, matrin-type 3
ZMYM3 zinc finger, MYM-type 3
ZNF124 zinc finger protein 124
ZNF215 zinc finger protein 215
ZNF273 zinc finger protein 273
ZNF33B zinc finger protein 33B
ZNF37BP zinc finger protein 37B, pseudogene
ZNF767P zinc finger family member 767, pseudogene
ZSCAN26 zinc finger and SCAN domain containing 26