gentamicin-5883 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the gentamicin-5883 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOC4 apolipoprotein C-IV
APOM apolipoprotein M
ARHGAP35 Rho GTPase activating protein 35
AUTS2 autism susceptibility candidate 2
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTF3P12 basic transcription factor 3 pseudogene 12
C5ORF42 chromosome 5 open reading frame 42
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD58 CD58 molecule
CD6 CD6 molecule
CDC14A cell division cycle 14A
CISH cytokine inducible SH2-containing protein
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL16A1 collagen, type XVI, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CROCC ciliary rootlet coiled-coil, rootletin
CRYGC crystallin, gamma C
CSF1R colony stimulating factor 1 receptor
DDIT3 DNA-damage-inducible transcript 3
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DLX2 distal-less homeobox 2
DNAL4 dynein, axonemal, light chain 4
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DPF3 D4, zinc and double PHD fingers, family 3
ERAP2 endoplasmic reticulum aminopeptidase 2
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FZD10 frizzled class receptor 10
GAS7 growth arrest-specific 7
GEMIN8 gem (nuclear organelle) associated protein 8
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HOXC5 homeobox C5
HSPB6 heat shock protein, alpha-crystallin-related, B6
IGHA1 immunoglobulin heavy constant alpha 1
INADL InaD-like (Drosophila)
INO80B INO80 complex subunit B
ITM2A integral membrane protein 2A
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLHL4 kelch-like family member 4
LIMK2 LIM domain kinase 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMAN1 lectin, mannose-binding, 1
LMO7 LIM domain 7
LRRK1 leucine-rich repeat kinase 1
MAPK7 mitogen-activated protein kinase 7
MBNL2 muscleblind-like splicing regulator 2
MBTPS1 membrane-bound transcription factor peptidase, site 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MID1 midline 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYF5 myogenic factor 5
MYRF myelin regulatory factor
NEBL nebulette
NF2 neurofibromin 2 (merlin)
NIPAL2 NIPA-like domain containing 2
NOTCH4 notch 4
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OSMR oncostatin M receptor
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAOX polyamine oxidase (exo-N4-amino)
PASK PAS domain containing serine/threonine kinase
PBX2 pre-B-cell leukemia homeobox 2
PDE4DIP phosphodiesterase 4D interacting protein
PIPOX pipecolic acid oxidase
PKP3 plakophilin 3
PNMAL1 paraneoplastic Ma antigen family-like 1
PTK7 protein tyrosine kinase 7 (inactive)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54B RAD54 homolog B (S. cerevisiae)
RARG retinoic acid receptor, gamma
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS17 regulator of G-protein signaling 17
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35F6 solute carrier family 35, member F6
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPRYD7 SPRY domain containing 7
TACC1 transforming, acidic coiled-coil containing protein 1
TAS2R10 taste receptor, type 2, member 10
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLE4 transducin-like enhancer of split 4
TM4SF5 transmembrane 4 L six family member 5
TMEM121 transmembrane protein 121
TMEM206 transmembrane protein 206
TMEM53 transmembrane protein 53
TMPRSS4 transmembrane protease, serine 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSPAN8 tetraspanin 8
UGT8 UDP glycosyltransferase 8
ZNF222 zinc finger protein 222
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ANAPC2 anaphase promoting complex subunit 2
ANG angiogenin, ribonuclease, RNase A family, 5
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATP7B ATPase, Cu++ transporting, beta polypeptide
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL2L2 BCL2-like 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
C19ORF24 chromosome 19 open reading frame 24
C1ORF115 chromosome 1 open reading frame 115
CA5BP1 carbonic anhydrase VB pseudogene 1
CASZ1 castor zinc finger 1
CCDC106 coiled-coil domain containing 106
CCNF cyclin F
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTNAP3B contactin associated protein-like 3B
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGKE diacylglycerol kinase, epsilon 64kDa
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
EDC3 enhancer of mRNA decapping 3
EN1 engrailed homeobox 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERF Ets2 repressor factor
EVPL envoplakin
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM53B family with sequence similarity 53, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXC1 forkhead box C1
FRS3 fibroblast growth factor receptor substrate 3
GJA8 gap junction protein, alpha 8, 50kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H2AM histone cluster 1, H2am
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HOXA7 homeobox A7
IL17RA interleukin 17 receptor A
INO80D INO80 complex subunit D
KIAA0556 KIAA0556
KIAA0753 KIAA0753
KIAA1462 KIAA1462
KLHL28 kelch-like family member 28
KRT31 keratin 31, type I
LPPR4 lipid phosphate phosphatase-related protein type 4
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYPD3 LY6/PLAUR domain containing 3
MED22 mediator complex subunit 22
MTERF4 mitochondrial transcription termination factor 4
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NRSN2 neurensin 2
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUD3 OTU deubiquitinase 3
OVGP1 oviductal glycoprotein 1, 120kDa
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAN2 PAN2 poly(A) specific ribonuclease subunit
PECR peroxisomal trans-2-enoyl-CoA reductase
PID1 phosphotyrosine interaction domain containing 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLM polymerase (DNA directed), mu
PORCN porcupine homolog (Drosophila)
PRMT7 protein arginine methyltransferase 7
PRPH peripherin
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB3A RAB3A, member RAS oncogene family
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SLC12A9 solute carrier family 12, member 9
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SNIP1 Smad nuclear interacting protein 1
STAG3 stromal antigen 3
STARD13 StAR-related lipid transfer (START) domain containing 13
TEP1 telomerase-associated protein 1
THBS3 thrombospondin 3
TMC7 transmembrane channel-like 7
TMEM132A transmembrane protein 132A
TMEM209 transmembrane protein 209
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM45 tripartite motif containing 45
TTC23 tetratricopeptide repeat domain 23
VN1R1 vomeronasal 1 receptor 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF253 zinc finger protein 253
ZNF263 zinc finger protein 263
ZNF276 zinc finger protein 276
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675