| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the gentamicin-5883 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| APOC4 | apolipoprotein C-IV |
| APOM | apolipoprotein M |
| ARHGAP35 | Rho GTPase activating protein 35 |
| AUTS2 | autism susceptibility candidate 2 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CD58 | CD58 molecule |
| CD6 | CD6 molecule |
| CDC14A | cell division cycle 14A |
| CISH | cytokine inducible SH2-containing protein |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| COL16A1 | collagen, type XVI, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CRYGC | crystallin, gamma C |
| CSF1R | colony stimulating factor 1 receptor |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DLX2 | distal-less homeobox 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FLT4 | fms-related tyrosine kinase 4 |
| FZD10 | frizzled class receptor 10 |
| GAS7 | growth arrest-specific 7 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| HOXC5 | homeobox C5 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| INADL | InaD-like (Drosophila) |
| INO80B | INO80 complex subunit B |
| ITM2A | integral membrane protein 2A |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLHL4 | kelch-like family member 4 |
| LIMK2 | LIM domain kinase 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LMAN1 | lectin, mannose-binding, 1 |
| LMO7 | LIM domain 7 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL7A | methyltransferase like 7A |
| MID1 | midline 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MYF5 | myogenic factor 5 |
| MYRF | myelin regulatory factor |
| NEBL | nebulette |
| NF2 | neurofibromin 2 (merlin) |
| NIPAL2 | NIPA-like domain containing 2 |
| NOTCH4 | notch 4 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OSMR | oncostatin M receptor |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PASK | PAS domain containing serine/threonine kinase |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIPOX | pipecolic acid oxidase |
| PKP3 | plakophilin 3 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RARG | retinoic acid receptor, gamma |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGS17 | regulator of G-protein signaling 17 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPRYD7 | SPRY domain containing 7 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLE4 | transducin-like enhancer of split 4 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM121 | transmembrane protein 121 |
| TMEM206 | transmembrane protein 206 |
| TMEM53 | transmembrane protein 53 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TSPAN8 | tetraspanin 8 |
| UGT8 | UDP glycosyltransferase 8 |
| ZNF222 | zinc finger protein 222 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL2L2 | BCL2-like 2 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CASZ1 | castor zinc finger 1 |
| CCDC106 | coiled-coil domain containing 106 |
| CCNF | cyclin F |
| CCNT1 | cyclin T1 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNTNAP3B | contactin associated protein-like 3B |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| EDC3 | enhancer of mRNA decapping 3 |
| EN1 | engrailed homeobox 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERF | Ets2 repressor factor |
| EVPL | envoplakin |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM53B | family with sequence similarity 53, member B |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOXC1 | forkhead box C1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3C | histone cluster 1, H3c |
| HIST1H3G | histone cluster 1, H3g |
| HOXA7 | homeobox A7 |
| IL17RA | interleukin 17 receptor A |
| INO80D | INO80 complex subunit D |
| KIAA0556 | KIAA0556 |
| KIAA0753 | KIAA0753 |
| KIAA1462 | KIAA1462 |
| KLHL28 | kelch-like family member 28 |
| KRT31 | keratin 31, type I |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MED22 | mediator complex subunit 22 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MVP | major vault protein |
| NDE1 | nudE neurodevelopment protein 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRSN2 | neurensin 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POLM | polymerase (DNA directed), mu |
| PORCN | porcupine homolog (Drosophila) |
| PRMT7 | protein arginine methyltransferase 7 |
| PRPH | peripherin |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB3A | RAB3A, member RAS oncogene family |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNIP1 | Smad nuclear interacting protein 1 |
| STAG3 | stromal antigen 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TEP1 | telomerase-associated protein 1 |
| THBS3 | thrombospondin 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM132A | transmembrane protein 132A |
| TMEM209 | transmembrane protein 209 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM45 | tripartite motif containing 45 |
| TTC23 | tetratricopeptide repeat domain 23 |
| VN1R1 | vomeronasal 1 receptor 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF253 | zinc finger protein 253 |
| ZNF263 | zinc finger protein 263 |
| ZNF276 | zinc finger protein 276 |
| ZNF442 | zinc finger protein 442 |
| ZNF675 | zinc finger protein 675 |