gentamicin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

47 genes differentially expressed following the gentamicin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CRYGB crystallin, gamma B 4.8878
CCDC71 coiled-coil domain containing 71 4.70072
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 4.30605
ZNF586 zinc finger protein 586 4.20348
ZNF134 zinc finger protein 134 4.12285
HMX1 H6 family homeobox 1 3.99374
TCF15 transcription factor 15 (basic helix-loop-helix) 3.96327
ZNF646 zinc finger protein 646 3.94048
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 3.92628
LINC02249 long intergenic non-protein coding RNA 2249 3.77219
B9D2 B9 protein domain 2 3.7721
PROZ protein Z, vitamin K-dependent plasma glycoprotein 3.69616
ETV7 ets variant 7 3.60649
ESRP2 epithelial splicing regulatory protein 2 3.4782
DPF1 D4, zinc and double PHD fingers family 1 3.46552
HDAC9 histone deacetylase 9 3.42292
IGFALS insulin-like growth factor binding protein, acid labile subunit 3.38941
CCDC33 coiled-coil domain containing 33 3.37624
BBC3 BCL2 binding component 3 3.33806
MYL10 myosin, light chain 10, regulatory 3.29344
ELAVL3 ELAV like neuron-specific RNA binding protein 3 3.26639
HAO2 hydroxyacid oxidase 2 (long chain) 3.24655
HMG20B high mobility group 20B 3.23416
SNPH syntaphilin 3.23391
MAP2K7 mitogen-activated protein kinase kinase 7 3.21317
IQCC IQ motif containing C 3.17544
TLE6 transducin-like enhancer of split 6 3.15172
MYOG myogenin (myogenic factor 4) 3.14809
PROC protein C (inactivator of coagulation factors Va and VIIIa) 3.13949
FAM182A family with sequence similarity 182, member A 3.11776
UNC93B1 unc-93 homolog B1 (C. elegans) 3.10501
EDA ectodysplasin A 3.08422
NPEPL1 aminopeptidase-like 1 3.02756
CLDN6 claudin 6 3.01977

decreased expression

Symbol Name Standardized Value
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.14595
PRLR prolactin receptor -3.61908
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -3.50344
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.49446
EBF2 early B-cell factor 2 -3.43528
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 -3.34477
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -3.3218
EPHB2 EPH receptor B2 -3.31965
GPR35 G protein-coupled receptor 35 -3.30976
SPOP speckle-type POZ protein -3.25631
CCDC85C coiled-coil domain containing 85C -3.24083
ISOC1 isochorismatase domain containing 1 -3.23447
MCTP1 multiple C2 domains, transmembrane 1 -3.23259