gentamicin Gene Set
Genes
47 genes differentially expressed following the gentamicin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CRYGB
|
crystallin, gamma B
|
4.8878
|
|
CCDC71
|
coiled-coil domain containing 71
|
4.70072
|
|
TNFRSF13B
|
tumor necrosis factor receptor superfamily, member 13B
|
4.30605
|
|
ZNF586
|
zinc finger protein 586
|
4.20348
|
|
ZNF134
|
zinc finger protein 134
|
4.12285
|
|
HMX1
|
H6 family homeobox 1
|
3.99374
|
|
TCF15
|
transcription factor 15 (basic helix-loop-helix)
|
3.96327
|
|
ZNF646
|
zinc finger protein 646
|
3.94048
|
|
YIF1B
|
Yip1 interacting factor homolog B (S. cerevisiae)
|
3.92628
|
|
LINC02249
|
long intergenic non-protein coding RNA 2249
|
3.77219
|
|
B9D2
|
B9 protein domain 2
|
3.7721
|
|
PROZ
|
protein Z, vitamin K-dependent plasma glycoprotein
|
3.69616
|
|
ETV7
|
ets variant 7
|
3.60649
|
|
ESRP2
|
epithelial splicing regulatory protein 2
|
3.4782
|
|
DPF1
|
D4, zinc and double PHD fingers family 1
|
3.46552
|
|
HDAC9
|
histone deacetylase 9
|
3.42292
|
|
IGFALS
|
insulin-like growth factor binding protein, acid labile subunit
|
3.38941
|
|
CCDC33
|
coiled-coil domain containing 33
|
3.37624
|
|
BBC3
|
BCL2 binding component 3
|
3.33806
|
|
MYL10
|
myosin, light chain 10, regulatory
|
3.29344
|
|
ELAVL3
|
ELAV like neuron-specific RNA binding protein 3
|
3.26639
|
|
HAO2
|
hydroxyacid oxidase 2 (long chain)
|
3.24655
|
|
HMG20B
|
high mobility group 20B
|
3.23416
|
|
SNPH
|
syntaphilin
|
3.23391
|
|
MAP2K7
|
mitogen-activated protein kinase kinase 7
|
3.21317
|
|
IQCC
|
IQ motif containing C
|
3.17544
|
|
TLE6
|
transducin-like enhancer of split 6
|
3.15172
|
|
MYOG
|
myogenin (myogenic factor 4)
|
3.14809
|
|
PROC
|
protein C (inactivator of coagulation factors Va and VIIIa)
|
3.13949
|
|
FAM182A
|
family with sequence similarity 182, member A
|
3.11776
|
|
UNC93B1
|
unc-93 homolog B1 (C. elegans)
|
3.10501
|
|
EDA
|
ectodysplasin A
|
3.08422
|
|
NPEPL1
|
aminopeptidase-like 1
|
3.02756
|
|
CLDN6
|
claudin 6
|
3.01977
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-4.14595
|
|
PRLR
|
prolactin receptor
|
-3.61908
|
|
SLC12A7
|
solute carrier family 12 (potassium/chloride transporter), member 7
|
-3.50344
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.49446
|
|
EBF2
|
early B-cell factor 2
|
-3.43528
|
|
KCNC3
|
potassium channel, voltage gated Shaw related subfamily C, member 3
|
-3.34477
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-3.3218
|
|
EPHB2
|
EPH receptor B2
|
-3.31965
|
|
GPR35
|
G protein-coupled receptor 35
|
-3.30976
|
|
SPOP
|
speckle-type POZ protein
|
-3.25631
|
|
CCDC85C
|
coiled-coil domain containing 85C
|
-3.24083
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.23447
|
|
MCTP1
|
multiple C2 domains, transmembrane 1
|
-3.23259
|