gfi1b Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description growth factor independent 1B transcription repressor|This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] (NCBI Entrez Gene Database, 8328)
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Genes

16 genes co-occuring with the biological term gfi1b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BCR breakpoint cluster region
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GFI1 growth factor independent 1 transcription repressor
GFI1B growth factor independent 1B transcription repressor
HMGB2 high mobility group box 2
KDM1A lysine (K)-specific demethylase 1A
POU2F1 POU class 2 homeobox 1
RCOR1 REST corepressor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
TAL1 T-cell acute lymphocytic leukemia 1
TCF3 transcription factor 3