giant Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

166 genes co-occuring with the biological term giant in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANO1 anoctamin 1, calcium activated chloride channel
AURKB aurora kinase B
BAG3 BCL2-associated athanogene 3
BANK1 B-cell scaffold protein with ankyrin repeats 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BLK BLK proto-oncogene, Src family tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSG basigin (Ok blood group)
C5 complement component 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCNA2 cyclin A2
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD14 CD14 molecule
CD226 CD226 molecule
CD24 CD24 molecule
CD33 CD33 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLU clusterin
COL1A1 collagen, type I, alpha 1
COL6A3 collagen, type VI, alpha 3
CSF1 colony stimulating factor 1 (macrophage)
CSK c-src tyrosine kinase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL5 chemokine (C-X-C motif) ligand 5
DCAF8 DDB1 and CUL4 associated factor 8
DCN decorin
DCSTAMP dendrocyte expressed seven transmembrane protein
DPT dermatopontin
EGFR epidermal growth factor receptor
ESR2 estrogen receptor 2 (ER beta)
F2R coagulation factor II (thrombin) receptor
FBLN1 fibulin 1
FGFR2 fibroblast growth factor receptor 2
FLNA filamin A, alpha
FSTL1 follistatin-like 1
GAN gigaxonin
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GJA1 gap junction protein, alpha 1, 43kDa
GLB1 galactosidase, beta 1
GP1BB glycoprotein Ib (platelet), beta polypeptide
HCK HCK proto-oncogene, Src family tyrosine kinase
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGF2 insulin-like growth factor 2
IGFBP4 insulin-like growth factor binding protein 4
IL10 interleukin 10
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL2 interleukin 2
IL21 interleukin 21
IL23R interleukin 23 receptor
IL32 interleukin 32
IL4 interleukin 4
IL6 interleukin 6
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IRAK1 interleukin-1 receptor-associated kinase 1
IRF5 interferon regulatory factor 5
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KTN1 kinectin 1 (kinesin receptor)
LUM lumican
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR126 microRNA 126
MIR30A microRNA 30a
MITF microphthalmia-associated transcription factor
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MSX1 msh homeobox 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYH9 myosin, heavy chain 9, non-muscle
NEFL neurofilament, light polypeptide
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NLRP1 NLR family, pyrin domain containing 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPN4 opsin 4
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPARA peroxisome proliferator-activated receptor alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX2 runt-related transcription factor 2
SELE selectin E
SH3BP2 SH3-domain binding protein 2
SOS1 son of sevenless homolog 1 (Drosophila)
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT4 signal transducer and activator of transcription 4
SYNE2 spectrin repeat containing, nuclear envelope 2
TBCB tubulin folding cofactor B
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TRAF1 TNF receptor-associated factor 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTN titin
TWIST1 twist family bHLH transcription factor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP6 ubiquitin specific peptidase 6
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
VWF von Willebrand factor
ZAK sterile alpha motif and leucine zipper containing kinase AZK