gingival Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The tissue that surrounds the necks of teeth and covers the alveolar parts of the jaws; broadly: the alveolar portion of a jaw with its enveloping soft tissues.|The soft tissue surrounding the neck of individual teeth as well as covering the alveolar bone. The tissue is fibrous and continuous with the periodontal ligament and mucosal covering. (Experimental Factor Ontology, EFO_0001925)
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Genes

159 genes co-occuring with the biological term gingival in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADM adrenomedullin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIM2 absent in melanoma 2
BCL2L1 BCL2-like 1
BDKRB2 bradykinin receptor B2
BIRC2 baculoviral IAP repeat containing 2
BSG basigin (Ok blood group)
CAMP cathelicidin antimicrobial peptide
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD14 CD14 molecule
CD151 CD151 molecule (Raph blood group)
CD180 CD180 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD9 CD9 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHEK2 checkpoint kinase 2
COL1A1 collagen, type I, alpha 1
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
DEC1 deleted in esophageal cancer 1
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DEFB1 defensin, beta 1
DEFB103A defensin, beta 103A
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DICER1 dicer 1, ribonuclease type III
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM20A family with sequence similarity 20, member A
FASLG Fas ligand (TNF superfamily, member 6)
FGF7 fibroblast growth factor 7
HACD1 3-hydroxyacyl-CoA dehydratase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
HSPG2 heparan sulfate proteoglycan 2
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGFBP5 insulin-like growth factor binding protein 5
IL10 interleukin 10
IL11 interleukin 11
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL2RA interleukin 2 receptor, alpha
IL34 interleukin 34
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JUN jun proto-oncogene
MAPK1 mitogen-activated protein kinase 1
MDK midkine (neurite growth-promoting factor 2)
MIR203A microRNA 203a
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MUC7 mucin 7, secreted
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP2 NLR family, pyrin domain containing 2
NLRP3 NLR family, pyrin domain containing 3
ODC1 ornithine decarboxylase 1
OSM oncostatin M
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PANX1 pannexin 1
PBX2 pre-B-cell leukemia homeobox 2
PDGFB platelet-derived growth factor beta polypeptide
PDPN podoplanin
PER1 period circadian clock 1
PER3 period circadian clock 3
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PON1 paraoxonase 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRTN3 proteinase 3
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB5A RAB5A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RB1 retinoblastoma 1
RHOA ras homolog family member A
RUNX2 runt-related transcription factor 2
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
SCX scleraxis basic helix-loop-helix transcription factor
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMAD2 SMAD family member 2
SMAD7 SMAD family member 7
SMC3 structural maintenance of chromosomes 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
TAC1 tachykinin, precursor 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TSC2 tuberous sclerosis 2
VEGFA vascular endothelial growth factor A