| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the glafenine-2387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOL2 | apolipoprotein L, 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| BMP7 | bone morphogenetic protein 7 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD200 | CD200 molecule |
| CD38 | CD38 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CHN2 | chimerin 2 |
| CLEC3B | C-type lectin domain family 3, member B |
| COL15A1 | collagen, type XV, alpha 1 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CUX1 | cut-like homeobox 1 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| F11R | F11 receptor |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGB | fibrinogen beta chain |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| FZD1 | frizzled class receptor 1 |
| G0S2 | G0/G1 switch 2 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GPR153 | G protein-coupled receptor 153 |
| H2AFX | H2A histone family, member X |
| HOMER3 | homer scaffolding protein 3 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL6ST | interleukin 6 signal transducer |
| INE1 | inactivation escape 1 (non-protein coding) |
| ING2 | inhibitor of growth family, member 2 |
| KIF13B | kinesin family member 13B |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KSR1 | kinase suppressor of ras 1 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRRC23 | leucine rich repeat containing 23 |
| LY96 | lymphocyte antigen 96 |
| MAPT | microtubule-associated protein tau |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFYA | nuclear transcription factor Y, alpha |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NRP1 | neuropilin 1 |
| PCGF2 | polycomb group ring finger 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCG1 | phospholipase C, gamma 1 |
| PLEK2 | pleckstrin 2 |
| PLSCR1 | phospholipid scramblase 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRSS22 | protease, serine, 22 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAP2B | RAP2B, member of RAS oncogene family |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SC5D | sterol-C5-desaturase |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SNN | stannin |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAPBP | TAP binding protein (tapasin) |
| TBL1X | transducin (beta)-like 1X-linked |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TSC22D4 | TSC22 domain family, member 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBOX5 | U-box domain containing 5 |
| VPS9D1 | VPS9 domain containing 1 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZMYM5 | zinc finger, MYM-type 5 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ADRB2 | adrenoceptor beta 2, surface |
| AGO4 | argonaute RISC catalytic component 4 |
| ALPK1 | alpha-kinase 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOBR | apolipoprotein B receptor |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARMC7 | armadillo repeat containing 7 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPN | asporin |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BBC3 | BCL2 binding component 3 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC176 | coiled-coil domain containing 176 |
| CCNT1 | cyclin T1 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DBF4B | DBF4 zinc finger B |
| DDN | dendrin |
| DENND2D | DENN/MADD domain containing 2D |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DYM | dymeclin |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECM1 | extracellular matrix protein 1 |
| FAM163A | family with sequence similarity 163, member A |
| FILIP1L | filamin A interacting protein 1-like |
| FOXN2 | forkhead box N2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRPR | gastrin-releasing peptide receptor |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HAL | histidine ammonia-lyase |
| HAMP | hepcidin antimicrobial peptide |
| HMG20A | high mobility group 20A |
| HOPX | HOP homeobox |
| HSPA4L | heat shock 70kDa protein 4-like |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IRF7 | interferon regulatory factor 7 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KIAA0753 | KIAA0753 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MEGF8 | multiple EGF-like-domains 8 |
| METRN | meteorin, glial cell differentiation regulator |
| MGAM | maltase-glucoamylase |
| MTA2 | metastasis associated 1 family, member 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NOTCH1 | notch 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDZD7 | PDZ domain containing 7 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PTDSS2 | phosphatidylserine synthase 2 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SALL2 | spalt-like transcription factor 2 |
| SCAI | suppressor of cancer cell invasion |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SERTAD3 | SERTA domain containing 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SNX16 | sorting nexin 16 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SPP1 | secreted phosphoprotein 1 |
| STXBP1 | syntaxin binding protein 1 |
| TASP1 | taspase, threonine aspartase, 1 |
| TEC | tec protein tyrosine kinase |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM127 | transmembrane protein 127 |
| TMEM209 | transmembrane protein 209 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC31 | tetratricopeptide repeat domain 31 |
| TUBA3C | tubulin, alpha 3c |
| UNC13B | unc-13 homolog B (C. elegans) |
| WASF3 | WAS protein family, member 3 |
| XAF1 | XIAP associated factor 1 |
| ZNF480 | zinc finger protein 480 |
| ZNF675 | zinc finger protein 675 |
| ZNF747 | zinc finger protein 747 |