glafenine-2387 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the glafenine-2387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APAF1 apoptotic peptidase activating factor 1
APOL2 apolipoprotein L, 2
ARNT aryl hydrocarbon receptor nuclear translocator
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BMP7 bone morphogenetic protein 7
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD200 CD200 molecule
CD38 CD38 molecule
CD59 CD59 molecule, complement regulatory protein
CHN2 chimerin 2
CLEC3B C-type lectin domain family 3, member B
COL15A1 collagen, type XV, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CRTC1 CREB regulated transcription coactivator 1
CUX1 cut-like homeobox 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
F11R F11 receptor
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGB fibrinogen beta chain
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
FZD1 frizzled class receptor 1
G0S2 G0/G1 switch 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAS2L1 growth arrest-specific 2 like 1
GPR153 G protein-coupled receptor 153
H2AFX H2A histone family, member X
HOMER3 homer scaffolding protein 3
HYAL3 hyaluronoglucosaminidase 3
IDI2-AS1 IDI2 antisense RNA 1
IL6ST interleukin 6 signal transducer
INE1 inactivation escape 1 (non-protein coding)
ING2 inhibitor of growth family, member 2
KIF13B kinesin family member 13B
KMT2A lysine (K)-specific methyltransferase 2A
KSR1 kinase suppressor of ras 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOC100287590 uncharacterized LOC100287590
LRRC23 leucine rich repeat containing 23
LY96 lymphocyte antigen 96
MAPT microtubule-associated protein tau
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFYA nuclear transcription factor Y, alpha
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRP1 neuropilin 1
PCGF2 polycomb group ring finger 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDLIM2 PDZ and LIM domain 2 (mystique)
PHACTR1 phosphatase and actin regulator 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCG1 phospholipase C, gamma 1
PLEK2 pleckstrin 2
PLSCR1 phospholipid scramblase 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRSS22 protease, serine, 22
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP2B RAP2B, member of RAS oncogene family
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SC5D sterol-C5-desaturase
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNN stannin
SOX15 SRY (sex determining region Y)-box 15
SS18 synovial sarcoma translocation, chromosome 18
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAPBP TAP binding protein (tapasin)
TBL1X transducin (beta)-like 1X-linked
TJAP1 tight junction associated protein 1 (peripheral)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPST1 tyrosylprotein sulfotransferase 1
TREM1 triggering receptor expressed on myeloid cells 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSC22D4 TSC22 domain family, member 4
TTLL1 tubulin tyrosine ligase-like family member 1
UBOX5 U-box domain containing 5
VPS9D1 VPS9 domain containing 1
ZBTB6 zinc finger and BTB domain containing 6
ZMYM5 zinc finger, MYM-type 5

decreased expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ADRB2 adrenoceptor beta 2, surface
AGO4 argonaute RISC catalytic component 4
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
AOAH acyloxyacyl hydrolase (neutrophil)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOBR apolipoprotein B receptor
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARMC7 armadillo repeat containing 7
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPN asporin
BAHCC1 BAH domain and coiled-coil containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBC3 BCL2 binding component 3
C6ORF47 chromosome 6 open reading frame 47
CCDC176 coiled-coil domain containing 176
CCNT1 cyclin T1
CD244 CD244 molecule, natural killer cell receptor 2B4
CDH10 cadherin 10, type 2 (T2-cadherin)
CECR1 cat eye syndrome chromosome region, candidate 1
CLCN6 chloride channel, voltage-sensitive 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYSLTR1 cysteinyl leukotriene receptor 1
DBF4B DBF4 zinc finger B
DDN dendrin
DENND2D DENN/MADD domain containing 2D
DKK2 dickkopf WNT signaling pathway inhibitor 2
DYM dymeclin
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECM1 extracellular matrix protein 1
FAM163A family with sequence similarity 163, member A
FILIP1L filamin A interacting protein 1-like
FOXN2 forkhead box N2
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAL histidine ammonia-lyase
HAMP hepcidin antimicrobial peptide
HMG20A high mobility group 20A
HOPX HOP homeobox
HSPA4L heat shock 70kDa protein 4-like
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF7 interferon regulatory factor 7
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KIAA0753 KIAA0753
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMP5 lysosomal-associated membrane protein family, member 5
LIN7A lin-7 homolog A (C. elegans)
LTBP2 latent transforming growth factor beta binding protein 2
MEGF8 multiple EGF-like-domains 8
METRN meteorin, glial cell differentiation regulator
MGAM maltase-glucoamylase
MTA2 metastasis associated 1 family, member 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NARFL nuclear prelamin A recognition factor-like
NOTCH1 notch 1
NPFFR1 neuropeptide FF receptor 1
PAQR6 progestin and adipoQ receptor family member VI
PCYOX1 prenylcysteine oxidase 1
PDZD7 PDZ domain containing 7
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRKG2 protein kinase, cGMP-dependent, type II
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTDSS2 phosphatidylserine synthase 2
PYCR1 pyrroline-5-carboxylate reductase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SALL2 spalt-like transcription factor 2
SCAI suppressor of cancer cell invasion
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SERTAD3 SERTA domain containing 3
SLC22A14 solute carrier family 22, member 14
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SNX16 sorting nexin 16
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
SPP1 secreted phosphoprotein 1
STXBP1 syntaxin binding protein 1
TASP1 taspase, threonine aspartase, 1
TEC tec protein tyrosine kinase
TM7SF2 transmembrane 7 superfamily member 2
TMEM127 transmembrane protein 127
TMEM209 transmembrane protein 209
TNRC6B trinucleotide repeat containing 6B
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC31 tetratricopeptide repeat domain 31
TUBA3C tubulin, alpha 3c
UNC13B unc-13 homolog B (C. elegans)
WASF3 WAS protein family, member 3
XAF1 XIAP associated factor 1
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747