| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the glafenine-7418 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AIM1L | absent in melanoma 1-like |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CA12 | carbonic anhydrase XII |
| CDHR2 | cadherin-related family member 2 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP350 | centrosomal protein 350kDa |
| CLDN1 | claudin 1 |
| CLMN | calmin (calponin-like, transmembrane) |
| COL8A1 | collagen, type VIII, alpha 1 |
| CTAGE5 | CTAGE family, member 5 |
| CTAGE9 | CTAGE family, member 9 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCT | dopachrome tautomerase |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DST | dystonin |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGR1 | early growth response 1 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FCMR | Fc fragment of IgM receptor |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FLT4 | fms-related tyrosine kinase 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GMPR | guanosine monophosphate reductase |
| GOLGA2 | golgin A2 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IDS | iduronate 2-sulfatase |
| IL1RN | interleukin 1 receptor antagonist |
| IL4R | interleukin 4 receptor |
| KAZN | kazrin, periplakin interacting protein |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA0319L | KIAA0319-like |
| KIF3C | kinesin family member 3C |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT8 | keratin 8, type II |
| LOC730101 | uncharacterized LOC730101 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MECP2 | methyl CpG binding protein 2 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| NF1 | neurofibromin 1 |
| OTUD3 | OTU deubiquitinase 3 |
| PDLIM5 | PDZ and LIM domain 5 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| POFUT1 | protein O-fucosyltransferase 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRMT2 | protein arginine methyltransferase 2 |
| PSKH1 | protein serine kinase H1 |
| PTN | pleiotrophin |
| RANBP3 | RAN binding protein 3 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBKS | ribokinase |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) |
| RNFT2 | ring finger protein, transmembrane 2 |
| RPL7 | ribosomal protein L7 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SETD4 | SET domain containing 4 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIRT3 | sirtuin 3 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLE2 | transducin-like enhancer of split 2 |
| TMEM63A | transmembrane protein 63A |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TTC9 | tetratricopeptide repeat domain 9 |
| UNC119 | unc-119 homolog (C. elegans) |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| USP20 | ubiquitin specific peptidase 20 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF571 | zinc finger protein 571 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAX | BCL2-associated X protein |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNL2 | cyclin L2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DEAF1 | DEAF1 transcription factor |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXOC5 | exocyst complex component 5 |
| FA2H | fatty acid 2-hydroxylase |
| FANCC | Fanconi anemia, complementation group C |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBP5 | FK506 binding protein 5 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GAS8 | growth arrest-specific 8 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GPR27 | G protein-coupled receptor 27 |
| GTF2I | general transcription factor IIi |
| H2AFY2 | H2A histone family, member Y2 |
| HIRA | histone cell cycle regulator |
| HMBOX1 | homeobox containing 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| ICK | intestinal cell (MAK-like) kinase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL17RA | interleukin 17 receptor A |
| INSIG1 | insulin induced gene 1 |
| IPO8 | importin 8 |
| IRF9 | interferon regulatory factor 9 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MMP9 | matrix metallopeptidase 9 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| NBAS | neuroblastoma amplified sequence |
| NUBPL | nucleotide binding protein-like |
| PADI2 | peptidyl arginine deiminase, type II |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PFDN6 | prefoldin subunit 6 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB32 | RAB32, member RAS oncogene family |
| RNF121 | ring finger protein 121 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH2D4A | SH2 domain containing 4A |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TESK1 | testis-specific kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TPCN1 | two pore segment channel 1 |
| TRIM25 | tripartite motif containing 25 |
| TUBA3C | tubulin, alpha 3c |
| WDR5B | WD repeat domain 5B |
| WDR60 | WD repeat domain 60 |
| WDR76 | WD repeat domain 76 |
| XYLT2 | xylosyltransferase II |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF248 | zinc finger protein 248 |
| ZNF286A | zinc finger protein 286A |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZNF586 | zinc finger protein 586 |
| ZNF7 | zinc finger protein 7 |
| ZNF8 | zinc finger protein 8 |
| ZNF813 | zinc finger protein 813 |