glafenine-7418 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the glafenine-7418 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
AIM1L absent in melanoma 1-like
AKAP11 A kinase (PRKA) anchor protein 11
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ARL4C ADP-ribosylation factor-like 4C
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASIC1 acid sensing (proton gated) ion channel 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CA12 carbonic anhydrase XII
CDHR2 cadherin-related family member 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP350 centrosomal protein 350kDa
CLDN1 claudin 1
CLMN calmin (calponin-like, transmembrane)
COL8A1 collagen, type VIII, alpha 1
CTAGE5 CTAGE family, member 5
CTAGE9 CTAGE family, member 9
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCT dopachrome tautomerase
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DHRS2 dehydrogenase/reductase (SDR family) member 2
DST dystonin
E2F4 E2F transcription factor 4, p107/p130-binding
EGR1 early growth response 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ELL2 elongation factor, RNA polymerase II, 2
ELP6 elongator acetyltransferase complex subunit 6
FCMR Fc fragment of IgM receptor
FER1L4 fer-1-like family member 4, pseudogene (functional)
FLT4 fms-related tyrosine kinase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GMPR guanosine monophosphate reductase
GOLGA2 golgin A2
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPG2 heparan sulfate proteoglycan 2
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IDS iduronate 2-sulfatase
IL1RN interleukin 1 receptor antagonist
IL4R interleukin 4 receptor
KAZN kazrin, periplakin interacting protein
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5A lysine (K)-specific demethylase 5A
KIAA0319L KIAA0319-like
KIF3C kinesin family member 3C
KLF3 Kruppel-like factor 3 (basic)
KRT8 keratin 8, type II
LOC730101 uncharacterized LOC730101
MAGOH2P mago-nashi homolog 2, pseudogene
MAN1C1 mannosidase, alpha, class 1C, member 1
MAST3 microtubule associated serine/threonine kinase 3
MECP2 methyl CpG binding protein 2
MTERF4 mitochondrial transcription termination factor 4
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NF1 neurofibromin 1
OTUD3 OTU deubiquitinase 3
PDLIM5 PDZ and LIM domain 5
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PILRB paired immunoglobin-like type 2 receptor beta
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POFUT1 protein O-fucosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRMT2 protein arginine methyltransferase 2
PSKH1 protein serine kinase H1
PTN pleiotrophin
RANBP3 RAN binding protein 3
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBKS ribokinase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REPS1 RALBP1 associated Eps domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNFT2 ring finger protein, transmembrane 2
RPL7 ribosomal protein L7
RPS4Y1 ribosomal protein S4, Y-linked 1
SETD4 SET domain containing 4
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRT3 sirtuin 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLE2 transducin-like enhancer of split 2
TMEM63A transmembrane protein 63A
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TTC9 tetratricopeptide repeat domain 9
UNC119 unc-119 homolog (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP20 ubiquitin specific peptidase 20
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene
ZNF571 zinc finger protein 571
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
BAX BCL2-associated X protein
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
CCDC9 coiled-coil domain containing 9
CCNL2 cyclin L2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CGREF1 cell growth regulator with EF-hand domain 1
COL9A2 collagen, type IX, alpha 2
CTNNBIP1 catenin, beta interacting protein 1
DEAF1 DEAF1 transcription factor
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
ETAA1 Ewing tumor-associated antigen 1
EXOC5 exocyst complex component 5
FA2H fatty acid 2-hydroxylase
FANCC Fanconi anemia, complementation group C
FBXL15 F-box and leucine-rich repeat protein 15
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
FRS2 fibroblast growth factor receptor substrate 2
GAREM GRB2 associated, regulator of MAPK1
GAS8 growth arrest-specific 8
GJA1 gap junction protein, alpha 1, 43kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR27 G protein-coupled receptor 27
GTF2I general transcription factor IIi
H2AFY2 H2A histone family, member Y2
HIRA histone cell cycle regulator
HMBOX1 homeobox containing 1
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
ICK intestinal cell (MAK-like) kinase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL17RA interleukin 17 receptor A
INSIG1 insulin induced gene 1
IPO8 importin 8
IRF9 interferon regulatory factor 9
LINC00115 long intergenic non-protein coding RNA 115
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC37A2 leucine rich repeat containing 37, member A2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MMP9 matrix metallopeptidase 9
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NBAS neuroblastoma amplified sequence
NUBPL nucleotide binding protein-like
PADI2 peptidyl arginine deiminase, type II
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PDZRN3 PDZ domain containing ring finger 3
PFDN6 prefoldin subunit 6
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYCRL pyrroline-5-carboxylate reductase-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB32 RAB32, member RAS oncogene family
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SGK1 serum/glucocorticoid regulated kinase 1
SH2D4A SH2 domain containing 4A
SIDT1 SID1 transmembrane family, member 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SNORA21 small nucleolar RNA, H/ACA box 21
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
TESK1 testis-specific kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THRAP3 thyroid hormone receptor associated protein 3
TPCN1 two pore segment channel 1
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
WDR5B WD repeat domain 5B
WDR60 WD repeat domain 60
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF248 zinc finger protein 248
ZNF286A zinc finger protein 286A
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480
ZNF586 zinc finger protein 586
ZNF7 zinc finger protein 7
ZNF8 zinc finger protein 8
ZNF813 zinc finger protein 813