glaucoma Gene Set

Dataset DISEASES Curated Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)|Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor. (Experimental Factor Ontology, EFO_0000516)
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Genes

10 genes involed in the disease glaucoma from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

Symbol Name
ASB10 ankyrin repeat and SOCS box containing 10
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
LOXL1 lysyl oxidase-like 1
LTBP2 latent transforming growth factor beta binding protein 2
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NTF4 neurotrophin 4
OPTN optineurin
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
TBK1 TANK-binding kinase 1
WDR36 WD repeat domain 36