glibenclamide-3163 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the glibenclamide-3163 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ADAMDEC1 ADAM-like, decysin 1
ADGRG3 adhesion G protein-coupled receptor G3
ADRB1 adrenoceptor beta 1
AKAP1 A kinase (PRKA) anchor protein 1
ARL3 ADP-ribosylation factor-like 3
ARPIN actin-related protein 2/3 complex inhibitor
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C14ORF1 chromosome 14 open reading frame 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALD1 caldesmon 1
CCDC28B coiled-coil domain containing 28B
CCDC30 coiled-coil domain containing 30
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CD4 CD4 molecule
CD84 CD84 molecule
CDHR2 cadherin-related family member 2
CDK13 cyclin-dependent kinase 13
CDRT1 CMT1A duplicated region transcript 1
CEP164 centrosomal protein 164kDa
COL4A2 collagen, type IV, alpha 2
CRHR2 corticotropin releasing hormone receptor 2
CRLF2 cytokine receptor-like factor 2
DCBLD2 discoidin, CUB and LCCL domain containing 2
DPYS dihydropyrimidinase
EMCN endomucin
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FGF16 fibroblast growth factor 16
FOXG1 forkhead box G1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GLUD2 glutamate dehydrogenase 2
GM2A GM2 ganglioside activator
GRM2 glutamate receptor, metabotropic 2
GSTA3 glutathione S-transferase alpha 3
HCG4 HLA complex group 4 (non-protein coding)
IGF1 insulin-like growth factor 1 (somatomedin C)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIAA0040 KIAA0040
KRT6B keratin 6B, type II
KSR1 kinase suppressor of ras 1
LAMA4 laminin, alpha 4
LECT2 leukocyte cell-derived chemotaxin 2
MBNL2 muscleblind-like splicing regulator 2
MCF2 MCF.2 cell line derived transforming sequence
MEG3 maternally expressed 3 (non-protein coding)
MORC1 MORC family CW-type zinc finger 1
MR1 major histocompatibility complex, class I-related
MUC2 mucin 2, oligomeric mucus/gel-forming
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NCOA2 nuclear receptor coactivator 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NID1 nidogen 1
NIN ninein (GSK3B interacting protein)
NUP214 nucleoporin 214kDa
PAX8 paired box 8
PCDH12 protocadherin 12
PCDHA5 protocadherin alpha 5
PHF7 PHD finger protein 7
PIGR polymeric immunoglobulin receptor
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
PPP5C protein phosphatase 5, catalytic subunit
PRAMEF10 PRAME family member 10
PSD4 pleckstrin and Sec7 domain containing 4
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTCRA pre T-cell antigen receptor alpha
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RCAN3 RCAN family member 3
RORA RAR-related orphan receptor A
RSU1 Ras suppressor protein 1
RTEL1 regulator of telomere elongation helicase 1
RUSC2 RUN and SH3 domain containing 2
S100A2 S100 calcium binding protein A2
SIGLEC8 sialic acid binding Ig-like lectin 8
SNPH syntaphilin
STK24 serine/threonine kinase 24
SZT2 seizure threshold 2 homolog (mouse)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFEC transcription factor EC
THEMIS2 thymocyte selection associated family member 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLL2 tolloid-like 2
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TTC28 tetratricopeptide repeat domain 28
WNT1 wingless-type MMTV integration site family, member 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YPEL1 yippee-like 1 (Drosophila)
ZIC3 Zic family member 3
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF41 zinc finger protein 41
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
AFAP1 actin filament associated protein 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P3 annexin A2 pseudogene 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
C14ORF93 chromosome 14 open reading frame 93
C2ORF44 chromosome 2 open reading frame 44
C8ORF60 chromosome 8 open reading frame 60
CAMKV CaM kinase-like vesicle-associated
CAPN15 calpain 15
CAPRIN2 caprin family member 2
CCDC88C coiled-coil domain containing 88C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDR2L cerebellar degeneration-related protein 2-like
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN6 chloride channel, voltage-sensitive 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORT cortistatin
CRY2 cryptochrome circadian clock 2
CST6 cystatin E/M
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DYSF dysferlin
FAM189A2 family with sequence similarity 189, member A2
FBXO22 F-box protein 22
FLRT3 fibronectin leucine rich transmembrane protein 3
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLI3 GLI family zinc finger 3
GMPR guanosine monophosphate reductase
GRB7 growth factor receptor-bound protein 7
GRTP1 growth hormone regulated TBC protein 1
HIRA histone cell cycle regulator
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL17RA interleukin 17 receptor A
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
LDHB lactate dehydrogenase B
LIN7B lin-7 homolog B (C. elegans)
LOC100287590 uncharacterized LOC100287590
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LYZ lysozyme
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MATK megakaryocyte-associated tyrosine kinase
MDM4 MDM4, p53 regulator
MED9 mediator complex subunit 9
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPO myeloperoxidase
MRPL52 mitochondrial ribosomal protein L52
MVD mevalonate (diphospho) decarboxylase
NRSN2 neurensin 2
NXPH4 neurexophilin 4
ONECUT2 one cut homeobox 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCDHA6 protocadherin alpha 6
PGPEP1 pyroglutamyl-peptidase I
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRR4 proline rich 4 (lacrimal)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFTN1 raftlin, lipid raft linker 1
S100A4 S100 calcium binding protein A4
SCGB2A2 secretoglobin, family 2A, member 2
SGK1 serum/glucocorticoid regulated kinase 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOCS7 suppressor of cytokine signaling 7
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
SRGN serglycin
STX5 syntaxin 5
SYT17 synaptotagmin XVII
TAOK1 TAO kinase 1
THBS3 thrombospondin 3
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TNRC6B trinucleotide repeat containing 6B
TOM1 target of myb1 (chicken)
TPST1 tyrosylprotein sulfotransferase 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF205 zinc finger protein 205
ZNF227 zinc finger protein 227
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF446 zinc finger protein 446
ZNF623 zinc finger protein 623