glibenclamide-7202 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the glibenclamide-7202 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AGMAT agmatine ureohydrolase (agmatinase)
ALK anaplastic lymphoma receptor tyrosine kinase
AMACR alpha-methylacyl-CoA racemase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC64 coiled-coil domain containing 64
CD7 CD7 molecule
CD82 CD82 molecule
CNTNAP2 contactin associated protein-like 2
CRYGC crystallin, gamma C
CTNS cystinosin, lysosomal cystine transporter
CXCL8 chemokine (C-X-C motif) ligand 8
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DLX4 distal-less homeobox 4
DPYS dihydropyrimidinase
EAF2 ELL associated factor 2
ELL2 elongation factor, RNA polymerase II, 2
EN2 engrailed homeobox 2
EXO5 exonuclease 5
FGFR3 fibroblast growth factor receptor 3
FRMD4B FERM domain containing 4B
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GM2A GM2 ganglioside activator
GPR137 G protein-coupled receptor 137
GSTP1 glutathione S-transferase pi 1
HFE hemochromatosis
HIST1H2BN histone cluster 1, H2bn
HIST1H3I histone cluster 1, H3i
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HR hair growth associated
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IAPP islet amyloid polypeptide
IGHA1 immunoglobulin heavy constant alpha 1
IGLJ3 immunoglobulin lambda joining 3
IL12B interleukin 12B
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KDM4C lysine (K)-specific demethylase 4C
KIAA1109 KIAA1109
KIF25 kinesin family member 25
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRT6B keratin 6B, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIN7A lin-7 homolog A (C. elegans)
LY86 lymphocyte antigen 86
MAPK7 mitogen-activated protein kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTA1 metastasis associated 1
MTA2 metastasis associated 1 family, member 2
MVP major vault protein
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NPVF neuropeptide VF precursor
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUD4 OTU deubiquitinase 4
PGAP3 post-GPI attachment to proteins 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
POM121 POM121 transmembrane nucleoporin
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRB1 proline-rich protein BstNI subfamily 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCA protein kinase C, alpha
PRR16 proline rich 16
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPRA protein tyrosine phosphatase, receptor type, A
PVR poliovirus receptor
RBM3 RNA binding motif (RNP1, RRM) protein 3
RCAN1 regulator of calcineurin 1
RNF170 ring finger protein 170
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SERHL2 serine hydrolase-like 2
SLC25A30 solute carrier family 25, member 30
SND1-IT1 SND1 intronic transcript 1
SPTBN4 spectrin, beta, non-erythrocytic 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSPN sarcospan
SYCE1L synaptonemal complex central element protein 1-like
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBX10 T-box 10
THAP3 THAP domain containing, apoptosis associated protein 3
THRB thyroid hormone receptor, beta
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM19 transmembrane protein 19
TMEM212 transmembrane protein 212
TUBA3C tubulin, alpha 3c
USP34 ubiquitin specific peptidase 34
VPRBP Vpr (HIV-1) binding protein
WIZ widely interspaced zinc finger motifs
ZBTB7A zinc finger and BTB domain containing 7A
ZMIZ2 zinc finger, MIZ-type containing 2
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BCL9 B-cell CLL/lymphoma 9
C10ORF88 chromosome 10 open reading frame 88
C14ORF132 chromosome 14 open reading frame 132
C1ORF159 chromosome 1 open reading frame 159
C9ORF40 chromosome 9 open reading frame 40
CALCOCO1 calcium binding and coiled-coil domain 1
CAMKMT calmodulin-lysine N-methyltransferase
CAMTA2 calmodulin binding transcription activator 2
CBX4 chromobox homolog 4
CD302 CD302 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP131 centrosomal protein 131kDa
CIDEC cell death-inducing DFFA-like effector c
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNM1 dynamin 1
EGR3 early growth response 3
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
ERCC4 excision repair cross-complementation group 4
ERO1L ERO1-like (S. cerevisiae)
EVPL envoplakin
FAM134C family with sequence similarity 134, member C
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GAB2 GRB2-associated binding protein 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMPPA GDP-mannose pyrophosphorylase A
HIST1H2BO histone cluster 1, H2bo
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KLHL2 kelch-like family member 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LNPEP leucyl/cystinyl aminopeptidase
MAMLD1 mastermind-like domain containing 1
MANBA mannosidase, beta A, lysosomal
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAST3 microtubule associated serine/threonine kinase 3
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MKS1 Meckel syndrome, type 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MNS1 meiosis-specific nuclear structural 1
MOGS mannosyl-oligosaccharide glucosidase
MORC3 MORC family CW-type zinc finger 3
MOSPD3 motile sperm domain containing 3
MRPL52 mitochondrial ribosomal protein L52
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYL5 myosin, light chain 5, regulatory
NBAS neuroblastoma amplified sequence
NPIPB15 nuclear pore complex interacting protein family, member B15
NUP62CL nucleoporin 62kDa C-terminal like
PARD6A par-6 family cell polarity regulator alpha
PARG poly (ADP-ribose) glycohydrolase
PC pyruvate carboxylase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POLH polymerase (DNA directed), eta
POLI polymerase (DNA directed) iota
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBL1 retinoblastoma-like 1
SAMHD1 SAM domain and HD domain 1
SAV1 salvador family WW domain containing protein 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SH2B3 SH2B adaptor protein 3
SLC12A9 solute carrier family 12, member 9
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNHG3 small nucleolar RNA host gene 3
SPIDR scaffolding protein involved in DNA repair
SUGP1 SURP and G patch domain containing 1
TET3 tet methylcytosine dioxygenase 3
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM62 transmembrane protein 62
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNK1 tyrosine kinase, non-receptor, 1
TNRC6B trinucleotide repeat containing 6B
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
ZBTB39 zinc finger and BTB domain containing 39
ZNF219 zinc finger protein 219
ZNF23 zinc finger protein 23
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675
ZNF767P zinc finger family member 767, pseudogene
ZNF8 zinc finger protein 8
ZNF813 zinc finger protein 813
ZXDC ZXD family zinc finger C