| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the gliclazide-1720 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APC | adenomatous polyposis coli |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BLVRA | biliverdin reductase A |
| BMP7 | bone morphogenetic protein 7 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CAPN5 | calpain 5 |
| CCDC64 | coiled-coil domain containing 64 |
| CD5 | CD5 molecule |
| CD70 | CD70 molecule |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEP152 | centrosomal protein 152kDa |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTTN | cortactin |
| CXORF56 | chromosome X open reading frame 56 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DSG2 | desmoglein 2 |
| DUS2 | dihydrouridine synthase 2 |
| EFNB3 | ephrin-B3 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| EMC9 | ER membrane protein complex subunit 9 |
| FAM134B | family with sequence similarity 134, member B |
| FAM214B | family with sequence similarity 214, member B |
| FASTK | Fas-activated serine/threonine kinase |
| FBLN1 | fibulin 1 |
| FBXO31 | F-box protein 31 |
| FHL1 | four and a half LIM domains 1 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| FOXO1 | forkhead box O1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GRB10 | growth factor receptor-bound protein 10 |
| HEMK1 | HemK methyltransferase family member 1 |
| HNF1A | HNF1 homeobox A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL21 | kelch-like family member 21 |
| KRT32 | keratin 32, type I |
| LPAR3 | lysophosphatidic acid receptor 3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MED20 | mediator complex subunit 20 |
| METTL13 | methyltransferase like 13 |
| MINK1 | misshapen-like kinase 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MPPE1 | metallophosphoesterase 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NPC1L1 | NPC1-like 1 |
| NUP210 | nucleoporin 210kDa |
| ODF2 | outer dense fiber of sperm tails 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCDHB6 | protocadherin beta 6 |
| PDCD6 | programmed cell death 6 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G5 | phospholipase A2, group V |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDM11 | PR domain containing 11 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB11B | RAB11B, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHOT2 | ras homolog family member T2 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| RNF216 | ring finger protein 216 |
| RUNX1 | runt-related transcription factor 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| TBC1D22A | TBC1 domain family, member 22A |
| TCTN1 | tectonic family member 1 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| UCN | urocortin |
| WDR13 | WD repeat domain 13 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| Symbol | Name |
|---|---|
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACVR1 | activin A receptor, type I |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATG7 | autophagy related 7 |
| ATP13A3 | ATPase type 13A3 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCOR | BCL6 corepressor |
| BRD9 | bromodomain containing 9 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| CCNT1 | cyclin T1 |
| CDC73 | cell division cycle 73 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| COMMD10 | COMM domain containing 10 |
| CTSK | cathepsin K |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DCTN4 | dynactin 4 (p62) |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DDHD2 | DDHD domain containing 2 |
| DERL2 | derlin 2 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DUSP5 | dual specificity phosphatase 5 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| EHD4 | EH-domain containing 4 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| EXOC5 | exocyst complex component 5 |
| EXOSC9 | exosome component 9 |
| FAM188A | family with sequence similarity 188, member A |
| FOXK2 | forkhead box K2 |
| FPGS | folylpolyglutamate synthase |
| GDI1 | GDP dissociation inhibitor 1 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GLOD4 | glyoxalase domain containing 4 |
| GPR18 | G protein-coupled receptor 18 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IL10RB | interleukin 10 receptor, beta |
| INTS12 | integrator complex subunit 12 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIAA0922 | KIAA0922 |
| KIAA1598 | |
| KNTC1 | kinetochore associated 1 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| MAD2L1BP | MAD2L1 binding protein |
| MATK | megakaryocyte-associated tyrosine kinase |
| MED17 | mediator complex subunit 17 |
| MEN1 | multiple endocrine neoplasia I |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MRPL28 | mitochondrial ribosomal protein L28 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NHLRC2 | NHL repeat containing 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NRBF2 | nuclear receptor binding factor 2 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| PFDN1 | prefoldin subunit 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PREP | prolyl endopeptidase |
| PSKH1 | protein serine kinase H1 |
| RBM14 | RNA binding motif protein 14 |
| RCOR1 | REST corepressor 1 |
| RNMTL1 | RNA methyltransferase like 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIRT1 | sirtuin 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| SUCO | SUN domain containing ossification factor |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TMEM14A | transmembrane protein 14A |
| TMEM53 | transmembrane protein 53 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM22 | tripartite motif containing 22 |
| TRIM45 | tripartite motif containing 45 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTPAL | tocopherol (alpha) transfer protein-like |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBL4A | ubiquitin-like 4A |
| USP8 | ubiquitin specific peptidase 8 |
| WASF1 | WAS protein family, member 1 |
| XYLT1 | xylosyltransferase I |
| YAF2 | YY1 associated factor 2 |
| ZNF280D | zinc finger protein 280D |
