gliclazide-2870 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the gliclazide-2870 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAMTSL3 ADAMTS-like 3
APAF1 apoptotic peptidase activating factor 1
ARTN artemin
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C10ORF95 chromosome 10 open reading frame 95
C19ORF66 chromosome 19 open reading frame 66
CA1 carbonic anhydrase I
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALML3 calmodulin-like 3
CD6 CD6 molecule
CDC25C cell division cycle 25C
CES3 carboxylesterase 3
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CNGB3 cyclic nucleotide gated channel beta 3
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
COLEC12 collectin sub-family member 12
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRTC1 CREB regulated transcription coactivator 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DLK2 delta-like 2 homolog (Drosophila)
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOCK10 dedicator of cytokinesis 10
DOK5 docking protein 5
DST dystonin
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FAM131A family with sequence similarity 131, member A
FAM149A family with sequence similarity 149, member A
FGF18 fibroblast growth factor 18
FGFR1OP FGFR1 oncogene partner
FLRT2 fibronectin leucine rich transmembrane protein 2
FYB FYN binding protein
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPC3 glypican 3
GPR15 G protein-coupled receptor 15
GSTTP1 glutathione S-transferase theta pseudogene 1
GZMK granzyme K (granzyme 3; tryptase II)
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H3J histone cluster 1, H3j
HMOX1 heme oxygenase 1
HOXA9 homeobox A9
IFNA2 interferon, alpha 2
IGF1 insulin-like growth factor 1 (somatomedin C)
KATNB1 katanin p80 (WD repeat containing) subunit B 1
LAMP1 lysosomal-associated membrane protein 1
LOC100131510 uncharacterized LOC100131510
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene
MALL mal, T-cell differentiation protein-like
MINK1 misshapen-like kinase 1
MOB3B MOB kinase activator 3B
NSUN6 NOP2/Sun domain family, member 6
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR1E1 olfactory receptor, family 1, subfamily E, member 1
PCBP3 poly(rC) binding protein 3
PDE4C phosphodiesterase 4C, cAMP-specific
PDPN podoplanin
PEAK1 pseudopodium-enriched atypical kinase 1
PHOX2B paired-like homeobox 2b
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP2 plakophilin 2
POFUT2 protein O-fucosyltransferase 2
PRB1 proline-rich protein BstNI subfamily 1
PRKCE protein kinase C, epsilon
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAP2A RAP2A, member of RAS oncogene family
RHAG Rh-associated glycoprotein
RHOH ras homolog family member H
RPL18 ribosomal protein L18
RPS11 ribosomal protein S11
SCN11A sodium channel, voltage gated, type XI alpha subunit
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIRPA signal-regulatory protein alpha
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SP4 Sp4 transcription factor
SPDEF SAM pointed domain containing ETS transcription factor
SPTA1 spectrin, alpha, erythrocytic 1
SQSTM1 sequestosome 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
TAOK2 TAO kinase 2
TAS2R1 taste receptor, type 2, member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFEB transcription factor EB
TGFB2 transforming growth factor, beta 2
TMPRSS15 transmembrane protease, serine 15
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TUBA3C tubulin, alpha 3c
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ULK4 unc-51 like kinase 4
WAS Wiskott-Aldrich syndrome
WDTC1 WD and tetratricopeptide repeats 1
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR2B activin A receptor, type IIB
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ARSB arylsulfatase B
BFSP1 beaded filament structural protein 1, filensin
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
CAPRIN2 caprin family member 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK3 cyclin-dependent kinase 3
CHRM3 cholinergic receptor, muscarinic 3
CLCF1 cardiotrophin-like cytokine factor 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYBG3 beta-gamma crystallin domain containing 3
CTNNBIP1 catenin, beta interacting protein 1
DGAT1 diacylglycerol O-acyltransferase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOCK1 dedicator of cytokinesis 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFHD2 EF-hand domain family, member D2
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
FAAH fatty acid amide hydrolase
FBXO5 F-box protein 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GPATCH3 G patch domain containing 3
GPR143 G protein-coupled receptor 143
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HEATR3 HEAT repeat containing 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
IGSF1 immunoglobulin superfamily, member 1
IRF9 interferon regulatory factor 9
KIAA0355 KIAA0355
L2HGDH L-2-hydroxyglutarate dehydrogenase
LINC00115 long intergenic non-protein coding RNA 115
LRP3 low density lipoprotein receptor-related protein 3
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP9 microtubule-associated protein 9
MTCP1 mature T-cell proliferation 1
MTG1 mitochondrial ribosome-associated GTPase 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5DC3 5'-nucleotidase domain containing 3
P3H1 prolyl 3-hydroxylase 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G10 phospholipase A2, group X
PRAF2 PRA1 domain family, member 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RSF1 remodeling and spacing factor 1
SCAND1 SCAN domain containing 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2B3 SH2B adaptor protein 3
SIK1 salt-inducible kinase 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMAD7 SMAD family member 7
SND1-IT1 SND1 intronic transcript 1
SPIDR scaffolding protein involved in DNA repair
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TH tyrosine hydroxylase
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMSB15A thymosin beta 15a
TNNT1 troponin T type 1 (skeletal, slow)
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC2 trafficking protein particle complex 2
TRIM5 tripartite motif containing 5
TRIM8 tripartite motif containing 8
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TTBK2 tau tubulin kinase 2
TUBA3D tubulin, alpha 3d
TWISTNB TWIST neighbor
USP6NL USP6 N-terminal like
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR33 WD repeat domain 33
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YEATS4 YEATS domain containing 4
YIPF3 Yip1 domain family, member 3
ZBTB25 zinc finger and BTB domain containing 25
ZBTB39 zinc finger and BTB domain containing 39
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF211 zinc finger protein 211
ZNF365 zinc finger protein 365
ZNF41 zinc finger protein 41
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516
ZNF532 zinc finger protein 532
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652