| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the gliclazide-5089 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACVR1B | activin A receptor, type IB |
| ADCY9 | adenylate cyclase 9 |
| AFF4 | AF4/FMR2 family, member 4 |
| AGRP | agouti related neuropeptide |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| APOC1 | apolipoprotein C-I |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| BCL2 | B-cell CLL/lymphoma 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD82 | CD82 molecule |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| COL8A1 | collagen, type VIII, alpha 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTBP2 | C-terminal binding protein 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DMC1 | DNA meiotic recombinase 1 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| FAM53B | family with sequence similarity 53, member B |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGFR2 | fibroblast growth factor receptor 2 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| HBP1 | HMG-box transcription factor 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HES2 | hes family bHLH transcription factor 2 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| IFT140 | intraflagellar transport 140 |
| INADL | InaD-like (Drosophila) |
| ITGA7 | integrin, alpha 7 |
| ITGB7 | integrin, beta 7 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LEFTY1 | left-right determination factor 1 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC75B | leucine rich repeat containing 75B |
| LRRN3 | leucine rich repeat neuronal 3 |
| LTC4S | leukotriene C4 synthase |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MEFV | Mediterranean fever |
| MGP | matrix Gla protein |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MVB12B | multivesicular body subunit 12B |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NELL2 | NEL-like 2 (chicken) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PBRM1 | polybromo 1 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PITX1 | paired-like homeodomain 1 |
| PKN2 | protein kinase N2 |
| PLA2G3 | phospholipase A2, group III |
| PLCE1 | phospholipase C, epsilon 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RFPL2 | ret finger protein-like 2 |
| RGS10 | regulator of G-protein signaling 10 |
| SAA3P | serum amyloid A3 pseudogene |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SFTPB | surfactant protein B |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STAB2 | stabilin 2 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D30 | TBC1 domain family, member 30 |
| TCF3 | transcription factor 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNXB | tenascin XB |
| TTC30A | tetratricopeptide repeat domain 30A |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZIC3 | Zic family member 3 |
| ZNF528 | zinc finger protein 528 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABT1 | activator of basal transcription 1 |
| AKTIP | AKT interacting protein |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANKRD36 | ankyrin repeat domain 36 |
| APOL6 | apolipoprotein L, 6 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BEX1 | brain expressed, X-linked 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLSPN | claspin |
| CNTLN | centlein, centrosomal protein |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| DLL3 | delta-like 3 (Drosophila) |
| DMXL1 | Dmx-like 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC5 | excision repair cross-complementation group 5 |
| ERF | Ets2 repressor factor |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO46 | F-box protein 46 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FZD7 | frizzled class receptor 7 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMIP | GEM interacting protein |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GRAMD4 | GRAM domain containing 4 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IL7R | interleukin 7 receptor |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF1 | interferon regulatory factor 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MBTD1 | mbt domain containing 1 |
| METTL16 | methyltransferase like 16 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MGC12488 | |
| MID1IP1 | MID1 interacting protein 1 |
| MMP13 | matrix metallopeptidase 13 |
| MTA2 | metastasis associated 1 family, member 2 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 |
| NLK | nemo-like kinase |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PEG3 | paternally expressed 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RINT1 | RAD50 interactor 1 |
| RNF121 | ring finger protein 121 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SDC3 | syndecan 3 |
| SESN1 | sestrin 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRAL2 | SIR2 antiphage like 2 |
| SIRT2 | sirtuin 2 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBX19 | T-box 19 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM132A | transmembrane protein 132A |
| TMEM2 | transmembrane protein 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TUBA3C | tubulin, alpha 3c |
| WDR91 | WD repeat domain 91 |
| YEATS2 | YEATS domain containing 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF136 | zinc finger protein 136 |
| ZNF197 | zinc finger protein 197 |
| ZNF215 | zinc finger protein 215 |
| ZNF552 | zinc finger protein 552 |
| ZNF701 | zinc finger protein 701 |
