| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the glimepiride-2154 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTSL4 | ADAMTS-like 4 |
| AFF4 | AF4/FMR2 family, member 4 |
| AMN | amnion associated transmembrane protein |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| AQP9 | aquaporin 9 |
| AURKA | aurora kinase A |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASZ1 | castor zinc finger 1 |
| CD300A | CD300a molecule |
| COL10A1 | collagen, type X, alpha 1 |
| CREM | cAMP responsive element modulator |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTRC | chymotrypsin C (caldecrin) |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| ENG | endoglin |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EXOSC2 | exosome component 2 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FAM110B | family with sequence similarity 110, member B |
| FAM65A | family with sequence similarity 65, member A |
| FANCA | Fanconi anemia, complementation group A |
| FBXO2 | F-box protein 2 |
| FCAR | Fc fragment of IgA receptor |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GPR3 | G protein-coupled receptor 3 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HPX | hemopexin |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL2RA | interleukin 2 receptor, alpha |
| INHBA | inhibin, beta A |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KLHL36 | kelch-like family member 36 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LTA | lymphotoxin alpha |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAP4 | microtubule-associated protein 4 |
| MED25 | mediator complex subunit 25 |
| MFAP3 | microfibrillar-associated protein 3 |
| MGLL | monoglyceride lipase |
| MTRF1L | mitochondrial translational release factor 1-like |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NIPAL2 | NIPA-like domain containing 2 |
| NNAT | neuronatin |
| NOV | nephroblastoma overexpressed |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PLAC4 | placenta-specific 4 |
| PLSCR3 | phospholipid scramblase 3 |
| PLXNA3 | plexin A3 |
| PQLC2 | PQ loop repeat containing 2 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RAB6B | RAB6B, member RAS oncogene family |
| RNASE3 | ribonuclease, RNase A family, 3 |
| S100A1 | S100 calcium binding protein A1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| SYN2 | synapsin II |
| TACR2 | tachykinin receptor 2 |
| TCF3 | transcription factor 3 |
| TGM2 | transglutaminase 2 |
| TMC7 | transmembrane channel-like 7 |
| TMEM140 | transmembrane protein 140 |
| TSKS | testis-specific serine kinase substrate |
| TSPAN14 | tetraspanin 14 |
| VCAN | versican |
| WFDC8 | WAP four-disulfide core domain 8 |
| WRAP53 | WD repeat containing, antisense to TP53 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF276 | zinc finger protein 276 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARSB | arylsulfatase B |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CAPN5 | calpain 5 |
| CDA | cytidine deaminase |
| CHM | choroideremia (Rab escort protein 1) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNMBP | dynamin binding protein |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| EGR2 | early growth response 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GID4 | GID complex subunit 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSR | glutathione reductase |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4D | histone cluster 1, H4d |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFT46 | intraflagellar transport 46 |
| IL22 | interleukin 22 |
| ISOC2 | isochorismatase domain containing 2 |
| KIAA0586 | KIAA0586 |
| LATS1 | large tumor suppressor kinase 1 |
| LOC729164 | hCG1732469 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MANSC1 | MANSC domain containing 1 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MKS1 | Meckel syndrome, type 1 |
| MTMR12 | myotubularin related protein 12 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYOZ3 | myozenin 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRBP1 | nuclear receptor binding protein 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLTP | phospholipid transfer protein |
| PMP22 | peripheral myelin protein 22 |
| PODNL1 | podocan-like 1 |
| POR | P450 (cytochrome) oxidoreductase |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| RAB17 | RAB17, member RAS oncogene family |
| RAB23 | RAB23, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RANBP17 | RAN binding protein 17 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAI1 | snail family zinc finger 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP4 | Sp4 transcription factor |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| TAGLN | transgelin |
| TCTN1 | tectonic family member 1 |
| TCTN2 | tectonic family member 2 |
| TFF2 | trefoil factor 2 |
| THEM6 | thioesterase superfamily member 6 |
| TMEM120B | transmembrane protein 120B |
| TMEM53 | transmembrane protein 53 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRIM25 | tripartite motif containing 25 |
| TRIM36 | tripartite motif containing 36 |
| TRIM45 | tripartite motif containing 45 |
| TSPAN5 | tetraspanin 5 |
| TUBA4B | tubulin, alpha 4b |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| URM1 | ubiquitin related modifier 1 |
| YY2 | YY2 transcription factor |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF528 | zinc finger protein 528 |
| ZNF747 | zinc finger protein 747 |
| ZNF787 | zinc finger protein 787 |