glipizide-1926 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the glipizide-1926 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADA adenosine deaminase
ADAP2 ArfGAP with dual PH domains 2
AEN apoptosis enhancing nuclease
AKR1C2 aldo-keto reductase family 1, member C2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOC1 apolipoprotein C-I
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ASB6 ankyrin repeat and SOCS box containing 6
ATXN2 ataxin 2
AXIN1 axin 1
BIK BCL2-interacting killer (apoptosis-inducing)
C9ORF16 chromosome 9 open reading frame 16
CALD1 caldesmon 1
CCRL2 chemokine (C-C motif) receptor-like 2
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIZ1 CDKN1A interacting zinc finger protein 1
CLDN3 claudin 3
CPE carboxypeptidase E
CPT2 carnitine palmitoyltransferase 2
CPTP ceramide-1-phosphate transfer protein
CUEDC1 CUE domain containing 1
CYB561 cytochrome b561
CYFIP2 cytoplasmic FMR1 interacting protein 2
DCXR dicarbonyl/L-xylulose reductase
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DENND2A DENN/MADD domain containing 2A
DTNA dystrobrevin, alpha
ENG endoglin
ENOSF1 enolase superfamily member 1
EPN3 epsin 3
ERCC2 excision repair cross-complementation group 2
FCGRT Fc fragment of IgG, receptor, transporter, alpha
GBX2 gastrulation brain homeobox 2
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
H2AFY2 H2A histone family, member Y2
HFE hemochromatosis
HOXB13 homeobox B13
HPS1 Hermansky-Pudlak syndrome 1
INA internexin neuronal intermediate filament protein, alpha
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF5A kinesin family member 5A
KLF6 Kruppel-like factor 6
KLK12 kallikrein-related peptidase 12
MICALL1 MICAL-like 1
MINK1 misshapen-like kinase 1
MMP25 matrix metallopeptidase 25
NME5 NME/NM23 family member 5
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP205 nucleoporin 205kDa
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLXNB2 plexin B2
PNO1 partner of NOB1 homolog (S. cerevisiae)
POU5F1B POU class 5 homeobox 1B
PRKCSH protein kinase C substrate 80K-H
PRKG2 protein kinase, cGMP-dependent, type II
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11B RAB11B, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RFXANK regulatory factor X-associated ankyrin-containing protein
RUNX1 runt-related transcription factor 1
RUSC2 RUN and SH3 domain containing 2
RXRA retinoid X receptor, alpha
SAMHD1 SAM domain and HD domain 1
SCARA3 scavenger receptor class A, member 3
SEC14L1 SEC14-like 1 (S. cerevisiae)
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMG5 SMG5 nonsense mediated mRNA decay factor
SMO smoothened, frizzled class receptor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPATA2 spermatogenesis associated 2
SPN sialophorin
SREBF1 sterol regulatory element binding transcription factor 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STK10 serine/threonine kinase 10
SUGP1 SURP and G patch domain containing 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TMEM161A transmembrane protein 161A
TPRA1 transmembrane protein, adipocyte asscociated 1
TTLL4 tubulin tyrosine ligase-like family member 4
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAC14 Vac14 homolog (S. cerevisiae)
ZNF211 zinc finger protein 211
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABI1 abl-interactor 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
AMOTL2 angiomotin like 2
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
APTX aprataxin
ARGLU1 arginine and glutamate rich 1
ARHGAP5 Rho GTPase activating protein 5
ARMT1 acidic residue methyltransferase 1
C17ORF85 chromosome 17 open reading frame 85
C1ORF109 chromosome 1 open reading frame 109
C5ORF22 chromosome 5 open reading frame 22
CD302 CD302 molecule
CDC73 cell division cycle 73
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHPF chondroitin polymerizing factor
CPOX coproporphyrinogen oxidase
CRY1 cryptochrome circadian clock 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDIT4 DNA-damage-inducible transcript 4
DMXL1 Dmx-like 1
DNA2 DNA replication helicase/nuclease 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPYD dihydropyrimidine dehydrogenase
DSN1 DSN1, MIS12 kinetochore complex component
EMC2 ER membrane protein complex subunit 2
ERMP1 endoplasmic reticulum metallopeptidase 1
FAM188A family with sequence similarity 188, member A
FBXL2 F-box and leucine-rich repeat protein 2
FBXO5 F-box protein 5
FZD6 frizzled class receptor 6
HACD2 3-hydroxyacyl-CoA dehydratase 2
HMGB2 high mobility group box 2
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
ISCU iron-sulfur cluster assembly enzyme
JRKL JRK-like
KIAA0753 KIAA0753
KIF18A kinesin family member 18A
KIF20B kinesin family member 20B
KIF23 kinesin family member 23
KLC2 kinesin light chain 2
KLF10 Kruppel-like factor 10
KRCC1 lysine-rich coiled-coil 1
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MICU2 mitochondrial calcium uptake 2
MID1IP1 MID1 interacting protein 1
MORC3 MORC family CW-type zinc finger 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYL12B myosin, light chain 12B, regulatory
NDFIP1 Nedd4 family interacting protein 1
NEK7 NIMA-related kinase 7
NOD1 nucleotide-binding oligomerization domain containing 1
NUP153 nucleoporin 153kDa
NUP43 nucleoporin 43kDa
OGFRL1 opioid growth factor receptor-like 1
ORC2 origin recognition complex, subunit 2
OSTM1 osteopetrosis associated transmembrane protein 1
PARG poly (ADP-ribose) glycohydrolase
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDCD10 programmed cell death 10
PSPH phosphoserine phosphatase
PTTG3P pituitary tumor-transforming 3, pseudogene
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RNF11 ring finger protein 11
RNF14 ring finger protein 14
RNF141 ring finger protein 141
RNF38 ring finger protein 38
RPAP3 RNA polymerase II associated protein 3
RPL23AP7 ribosomal protein L23a pseudogene 7
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SH2D2A SH2 domain containing 2A
SHCBP1 SHC SH2-domain binding protein 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLMO2 slowmo homolog 2 (Drosophila)
SP3 Sp3 transcription factor
SPAG1 sperm associated antigen 1
STAC SH3 and cysteine rich domain
TDRD7 tudor domain containing 7
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TPCN1 two pore segment channel 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TUBA3C tubulin, alpha 3c
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBXN2B UBX domain protein 2B
UFM1 ubiquitin-fold modifier 1
UGDH UDP-glucose 6-dehydrogenase
UNG uracil-DNA glycosylase
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WASF1 WAS protein family, member 1
WDR11 WD repeat domain 11
WDR47 WD repeat domain 47
WLS wntless Wnt ligand secretion mediator
WRN Werner syndrome, RecQ helicase-like
YAP1 Yes-associated protein 1
ZMYM3 zinc finger, MYM-type 3
ZNF189 zinc finger protein 189
ZNF580 zinc finger protein 580