glipizide-2008 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the glipizide-2008 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACBD4 acyl-CoA binding domain containing 4
AHI1 Abelson helper integration site 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
BLK BLK proto-oncogene, Src family tyrosine kinase
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CA5BP1 carbonic anhydrase VB pseudogene 1
CACFD1 calcium channel flower domain containing 1
CACYBP calcyclin binding protein
CAMKMT calmodulin-lysine N-methyltransferase
CAST calpastatin
CCPG1 cell cycle progression 1
CD22 CD22 molecule
CDHR2 cadherin-related family member 2
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CENPT centromere protein T
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEC cell death-inducing DFFA-like effector c
CLDN11 claudin 11
CRYM crystallin, mu
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYB561 cytochrome b561
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
EPHA1 EPH receptor A1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPX eosinophil peroxidase
FAM134B family with sequence similarity 134, member B
FASTK Fas-activated serine/threonine kinase
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FKBP6 FK506 binding protein 6, 36kDa
FYB FYN binding protein
G6PD glucose-6-phosphate dehydrogenase
GABPB1 GA binding protein transcription factor, beta subunit 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GSK3A glycogen synthase kinase 3 alpha
GTSE1 G-2 and S-phase expressed 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFITM3 interferon induced transmembrane protein 3
IGHM immunoglobulin heavy constant mu
IQSEC1 IQ motif and Sec7 domain 1
IRF2 interferon regulatory factor 2
ITSN1 intersectin 1 (SH3 domain protein)
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLHL18 kelch-like family member 18
KRT32 keratin 32, type I
LAD1 ladinin 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LPPR2 lipid phosphate phosphatase-related protein type 2
LTB4R leukotriene B4 receptor
MASP2 mannan-binding lectin serine peptidase 2
MCTP2 multiple C2 domains, transmembrane 2
MED27 mediator complex subunit 27
MSH3 mutS homolog 3
MST1 macrophage stimulating 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTMR3 myotubularin related protein 3
N4BP1 NEDD4 binding protein 1
N4BP2L1 NEDD4 binding protein 2-like 1
NADK NAD kinase
NPEPL1 aminopeptidase-like 1
PBX2 pre-B-cell leukemia homeobox 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGC progastricsin (pepsinogen C)
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PID1 phosphotyrosine interaction domain containing 1
PLEK2 pleckstrin 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP6R2 protein phosphatase 6, regulatory subunit 2
PSD4 pleckstrin and Sec7 domain containing 4
RAP1GAP RAP1 GTPase activating protein
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF144A ring finger protein 144A
SDC2 syndecan 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNX19 sorting nexin 19
SUGP1 SURP and G patch domain containing 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYMPK symplekin
SYT13 synaptotagmin XIII
TBL1X transducin (beta)-like 1X-linked
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFE3 transcription factor binding to IGHM enhancer 3
TMPRSS5 transmembrane protease, serine 5
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TP63 tumor protein p63
TRAC T cell receptor alpha constant
USP46 ubiquitin specific peptidase 46
VPRBP Vpr (HIV-1) binding protein
ZNF219 zinc finger protein 219
ZNF224 zinc finger protein 224
ZNF23 zinc finger protein 23
ZNF518A zinc finger protein 518A
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AHR aryl hydrocarbon receptor
ARG1 arginase 1
ATAT1 alpha tubulin acetyltransferase 1
ATXN2 ataxin 2
B3GNT1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C17ORF70 chromosome 17 open reading frame 70
C5ORF15 chromosome 5 open reading frame 15
CD244 CD244 molecule, natural killer cell receptor 2B4
CD248 CD248 molecule, endosialin
CDC25B cell division cycle 25B
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP170B centrosomal protein 170B
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTD2 cyclin N-terminal domain containing 2
CSRNP2 cysteine-serine-rich nuclear protein 2
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DBR1 debranching RNA lariats 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DEAF1 DEAF1 transcription factor
DENND1A DENN/MADD domain containing 1A
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ECM1 extracellular matrix protein 1
ELP5 elongator acetyltransferase complex subunit 5
ERCC6L excision repair cross-complementation group 6-like
EXOC5 exocyst complex component 5
FAF1 Fas (TNFRSF6) associated factor 1
FANCF Fanconi anemia, complementation group F
FBRS fibrosin
FOXM1 forkhead box M1
HACD3 3-hydroxyacyl-CoA dehydratase 3
HIST1H2BF histone cluster 1, H2bf
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INO80D INO80 complex subunit D
ITPKC inositol-trisphosphate 3-kinase C
JRKL JRK-like
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF18A kinesin family member 18A
KIFAP3 kinesin-associated protein 3
LOC729164 hCG1732469
MAPKAP1 mitogen-activated protein kinase associated protein 1
MNS1 meiosis-specific nuclear structural 1
MON1B MON1 secretory trafficking family member B
MTERF4 mitochondrial transcription termination factor 4
MTMR11 myotubularin related protein 11
MX2 MX dynamin-like GTPase 2
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NEK11 NIMA-related kinase 11
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALM paralemmin
PCSK7 proprotein convertase subtilisin/kexin type 7
PDZD8 PDZ domain containing 8
PGPEP1 pyroglutamyl-peptidase I
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMEL premelanosome protein
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PSKH1 protein serine kinase H1
RECQL4 RecQ protein-like 4
RNASE6 ribonuclease, RNase A family, k6
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF170 ring finger protein 170
S1PR4 sphingosine-1-phosphate receptor 4
SATB1 SATB homeobox 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMC6 structural maintenance of chromosomes 6
STXBP2 syntaxin binding protein 2
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TMEM127 transmembrane protein 127
TMEM14A transmembrane protein 14A
TMPRSS6 transmembrane protease, serine 6
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM22 tripartite motif containing 22
TRIM45 tripartite motif containing 45
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
UNC93B1 unc-93 homolog B1 (C. elegans)
UNKL unkempt family zinc finger-like
VASP vasodilator-stimulated phosphoprotein
VILL villin-like
XDH xanthine dehydrogenase
ZBTB39 zinc finger and BTB domain containing 39
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF134 zinc finger protein 134
ZNF32 zinc finger protein 32
ZNF536 zinc finger protein 536
ZNF606 zinc finger protein 606
ZNF804A zinc finger protein 804A