| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the glipizide-4991 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ART1 | ADP-ribosyltransferase 1 |
| ATN1 | atrophin 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CD58 | CD58 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHN2 | chimerin 2 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CUL7 | cullin 7 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DAPK2 | death-associated protein kinase 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR6L | DiGeorge syndrome critical region gene 6-like |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EDNRA | endothelin receptor type A |
| FSCN1 | fascin actin-bundling protein 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNAS | GNAS complex locus |
| GRPR | gastrin-releasing peptide receptor |
| HAMP | hepcidin antimicrobial peptide |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL11 | interleukin 11 |
| IL1B | interleukin 1, beta |
| IL2 | interleukin 2 |
| ITGA7 | integrin, alpha 7 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LENEP | lens epithelial protein |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMF1 | lipase maturation factor 1 |
| LMF2 | lipase maturation factor 2 |
| LMX1B | LIM homeobox transcription factor 1, beta |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| METTL7A | methyltransferase like 7A |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PLXNB3 | plexin B3 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RAPSN | receptor-associated protein of the synapse |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RGS20 | regulator of G-protein signaling 20 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SECTM1 | secreted and transmembrane 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERHL2 | serine hydrolase-like 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIX3 | SIX homeobox 3 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SMC1A | structural maintenance of chromosomes 1A |
| SPAG8 | sperm associated antigen 8 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| STAB2 | stabilin 2 |
| STATH | statherin |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| TK2 | thymidine kinase 2, mitochondrial |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TYMS | thymidylate synthetase |
| USP22 | ubiquitin specific peptidase 22 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| XAF1 | XIAP associated factor 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF440 | zinc finger protein 440 |
| ZNF552 | zinc finger protein 552 |
| ZNF614 | zinc finger protein 614 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANKRD36 | ankyrin repeat domain 36 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BAGE | B melanoma antigen |
| BBC3 | BCL2 binding component 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAPRIN2 | caprin family member 2 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CD302 | CD302 molecule |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| FAM184A | family with sequence similarity 184, member A |
| FBXO22 | F-box protein 22 |
| FCF1 | FCF1 rRNA-processing protein |
| FEM1C | fem-1 homolog c (C. elegans) |
| FER | fer (fps/fes related) tyrosine kinase |
| FRK | fyn-related Src family tyrosine kinase |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GLCE | glucuronic acid epimerase |
| GPR1 | G protein-coupled receptor 1 |
| IL15RA | interleukin 15 receptor, alpha |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF13B | kinesin family member 13B |
| KLHL9 | kelch-like family member 9 |
| LAMA3 | laminin, alpha 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL2B | methyltransferase like 2B |
| METTL8 | methyltransferase like 8 |
| MGC12488 | |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MTA2 | metastasis associated 1 family, member 2 |
| N4BP3 | NEDD4 binding protein 3 |
| NME5 | NME/NM23 family member 5 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OSMR | oncostatin M receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PROS1 | protein S (alpha) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASA2 | RAS p21 protein activator 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF122 | ring finger protein 122 |
| RNF146 | ring finger protein 146 |
| RNF170 | ring finger protein 170 |
| RNF25 | ring finger protein 25 |
| ROM1 | retinal outer segment membrane protein 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RRAGB | Ras-related GTP binding B |
| SHROOM2 | shroom family member 2 |
| SIRT6 | sirtuin 6 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TET3 | tet methylcytosine dioxygenase 3 |
| TOM1 | target of myb1 (chicken) |
| TRIM66 | tripartite motif containing 66 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN1 | tetraspanin 1 |
| TTBK2 | tau tubulin kinase 2 |
| TUBG2 | tubulin, gamma 2 |
| UBXN6 | UBX domain protein 6 |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR19 | WD repeat domain 19 |
| XK | X-linked Kx blood group |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
| ZNF675 | zinc finger protein 675 |
| ZNF74 | zinc finger protein 74 |
| ZNF778 | zinc finger protein 778 |
| ZNF8 | zinc finger protein 8 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
