gliquidone-6505 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the gliquidone-6505 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AGO4 argonaute RISC catalytic component 4
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BGN biglycan
C14ORF105 chromosome 14 open reading frame 105
C3ORF18 chromosome 3 open reading frame 18
C5ORF30 chromosome 5 open reading frame 30
CD6 CD6 molecule
CHGB chromogranin B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CMKLR1 chemerin chemokine-like receptor 1
COMT catechol-O-methyltransferase
CPN2 carboxypeptidase N, polypeptide 2
CRISP2 cysteine-rich secretory protein 2
DESI2 desumoylating isopeptidase 2
DMPK dystrophia myotonica-protein kinase
EDNRA endothelin receptor type A
EFNA3 ephrin-A3
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHA1 EPH receptor A1
ERC2-IT1 ERC2 intronic transcript 1
EXOSC1 exosome component 1
FAM76A family with sequence similarity 76, member A
FGF17 fibroblast growth factor 17
FLRT2 fibronectin leucine rich transmembrane protein 2
GLG1 golgi glycoprotein 1
GLS glutaminase
GPC1 glypican 1
GRM3 glutamate receptor, metabotropic 3
GSTA3 glutathione S-transferase alpha 3
HOMER3 homer scaffolding protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
HPSE2 heparanase 2 (inactive)
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFFO1 intermediate filament family orphan 1
ING1 inhibitor of growth family, member 1
IQCK IQ motif containing K
JAK2 Janus kinase 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KRT12 keratin 12, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC2 laminin, gamma 2
LHX6 LIM homeobox 6
MATN1 matrilin 1, cartilage matrix protein
MAX MYC associated factor X
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MR1 major histocompatibility complex, class I-related
MST1 macrophage stimulating 1
NRN1 neuritin 1
OCA2 oculocutaneous albinism II
PACRG PARK2 co-regulated
PDE4DIP phosphodiesterase 4D interacting protein
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
POFUT1 protein O-fucosyltransferase 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS12 regulator of G-protein signaling 12
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SATB2 SATB homeobox 2
SBF1 SET binding factor 1
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNRPN small nuclear ribonucleoprotein polypeptide N
SORBS1 sorbin and SH3 domain containing 1
SPATA6 spermatogenesis associated 6
SRPK2 SRSF protein kinase 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYT13 synaptotagmin XIII
TAPBP TAP binding protein (tapasin)
TESPA1 thymocyte expressed, positive selection associated 1
TEX14 testis expressed 14
THRB thyroid hormone receptor, beta
TLN1 talin 1
TMEM242 transmembrane protein 242
TMPRSS3 transmembrane protease, serine 3
TP63 tumor protein p63
TRA T cell receptor alpha locus
TSSK2 testis-specific serine kinase 2
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UTRN utrophin
WIPI2 WD repeat domain, phosphoinositide interacting 2
WNK1 WNK lysine deficient protein kinase 1
YIPF4 Yip1 domain family, member 4
ZBTB39 zinc finger and BTB domain containing 39
ZNF510 zinc finger protein 510
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRA3 adhesion G protein-coupled receptor A3
ADGRG2 adhesion G protein-coupled receptor G2
AMT aminomethyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARR3 arrestin 3, retinal (X-arrestin)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAG4 BCL2-associated athanogene 4
BBS7 Bardet-Biedl syndrome 7
BIRC7 baculoviral IAP repeat containing 7
C17ORF80 chromosome 17 open reading frame 80
C2ORF27A chromosome 2 open reading frame 27A
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASD1 CAS1 domain containing 1
CCDC9 coiled-coil domain containing 9
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDH10 cadherin 10, type 2 (T2-cadherin)
CDKN2AIP CDKN2A interacting protein
CHEK2 checkpoint kinase 2
CHST10 carbohydrate sulfotransferase 10
CLDND1 claudin domain containing 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COMMD10 COMM domain containing 10
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EAF2 ELL associated factor 2
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FBRS fibrosin
FBXL6 F-box and leucine-rich repeat protein 6
GADD45G growth arrest and DNA-damage-inducible, gamma
GALK1 galactokinase 1
GAR1 GAR1 ribonucleoprotein
GPR87 G protein-coupled receptor 87
GRPR gastrin-releasing peptide receptor
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HIST1H4F histone cluster 1, H4f
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIFAP3 kinesin-associated protein 3
LAMP3 lysosomal-associated membrane protein 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LYRM9 LYR motif containing 9
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBTPS2 membrane-bound transcription factor peptidase, site 2
MTMR12 myotubularin related protein 12
MTSS1L metastasis suppressor 1-like
MYO1D myosin ID
NARFL nuclear prelamin A recognition factor-like
NBEAL2 neurobeachin-like 2
NIPAL2 NIPA-like domain containing 2
NMU neuromedin U
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB3 protocadherin beta 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RARS arginyl-tRNA synthetase
RNF122 ring finger protein 122
SCN10A sodium channel, voltage gated, type X alpha subunit
SCPEP1 serine carboxypeptidase 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A6 solute carrier family 16, member 6
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TEX30 testis expressed 30
TM7SF3 transmembrane 7 superfamily member 3
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAPPC13 trafficking protein particle complex 13
TSPAN2 tetraspanin 2
TSSC4 tumor suppressing subtransferable candidate 4
TTC4 tetratricopeptide repeat domain 4
TTLL1 tubulin tyrosine ligase-like family member 1
TUBG2 tubulin, gamma 2
TWSG1 twisted gastrulation BMP signaling modulator 1
USP18 ubiquitin specific peptidase 18
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZBTB22 zinc finger and BTB domain containing 22
ZFHX2 zinc finger homeobox 2
ZNF219 zinc finger protein 219
ZNF35 zinc finger protein 35
ZNF492 zinc finger protein 492
ZNF74 zinc finger protein 74
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26