global brain atrophy Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Unlocalized atrophy of the brain with decreased total brain matter volume and increased ventricular size. (Human Phenotype Ontology, HP_0002283)
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10 genes associated with the global brain atrophy phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
GFM1 G elongation factor, mitochondrial 1
L2HGDH L-2-hydroxyglutarate dehydrogenase
PANK2 pantothenate kinase 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PRNP prion protein
PSAP prosaposin
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
WDR81 WD repeat domain 81