globozoospermia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Any structural anomaly of the acrosome resulting in a round sperm head. (Human Phenotype Ontology, HP_0012205)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002686
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Genes

31 gene mutations causing the globozoospermia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGFG1 ArfGAP with FG repeats 1
AKAP9 A kinase (PRKA) anchor protein 9
BRWD1 bromodomain and WD repeat domain containing 1
CADM1 cell adhesion molecule 1
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DPCD deleted in primary ciliary dyskinesia homolog (mouse)
DPY19L2 dpy-19-like 2 (C. elegans)
GBA2 glucosidase, beta (bile acid) 2
GMCL1 germ cell-less, spermatogenesis associated 1
GOLGA3 golgin A3
GOPC golgi-associated PDZ and coiled-coil motif containing
ING2 inhibitor of growth family, member 2
JAM3 junctional adhesion molecule 3
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KMT2E lysine (K)-specific methyltransferase 2E
M1AP meiosis 1 associated protein
PICK1 protein interacting with PRKCA 1
PLA2G3 phospholipase A2, group III
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
SEC23IP SEC23 interacting protein
SEPT12 septin 12
SIRT1 sirtuin 1
SPACA1 sperm acrosome associated 1
STYX serine/threonine/tyrosine interacting protein
TDRD5 tudor domain containing 5
TMF1 TATA element modulatory factor 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZPBP zona pellucida binding protein