glomerulonephritis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A nephritis that causes inflammation of the glomeruli located_in kidney. (Human Disease Ontology, DOID_2921)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002743
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Genes

81 gene mutations causing the glomerulonephritis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ANK1 ankyrin 1, erythrocytic
APCS amyloid P component, serum
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
CCR1 chemokine (C-C motif) receptor 1
CD1D CD1d molecule
CD72 CD72 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFH complement factor H
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CORO1A coronin, actin binding protein, 1A
DNASE1 deoxyribonuclease I
DTX1 deltex 1, E3 ubiquitin ligase
E2F2 E2F transcription factor 2
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GLIS2 GLIS family zinc finger 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPX7 glutathione peroxidase 7
GSTK1 glutathione S-transferase kappa 1
HMOX1 heme oxygenase 1
HR hair growth associated
IFNG interferon, gamma
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL12RB2 interleukin 12 receptor, beta 2
LAMB2 laminin, beta 2 (laminin S)
LAT linker for activation of T cells
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN2A1 mannosidase, alpha, class 2A, member 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MET MET proto-oncogene, receptor tyrosine kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTA2 metastasis associated 1 family, member 2
MTUS1 microtubule associated tumor suppressor 1
NFE2L2 nuclear factor, erythroid 2-like 2
PDCD1 programmed cell death 1
PGM3 phosphoglucomutase 3
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKN1 protein kinase N1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLB polymerase (DNA directed), beta
PRKCD protein kinase C, delta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RC3H1 ring finger and CCCH-type domains 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL22 ribosomal protein L22
SCARF1 scavenger receptor class F, member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIAE sialic acid acetylesterase
SIRT1 sirtuin 1
SOCS1 suppressor of cytokine signaling 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SYK spleen tyrosine kinase
TANK TRAF family member-associated NFKB activator
TLR8 toll-like receptor 8
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNIP1 TNFAIP3 interacting protein 1
TNS2 tensin 2
TOP3B topoisomerase (DNA) III beta
TRAF3IP2 TRAF3 interacting protein 2
TREX1 three prime repair exonuclease 1
TROVE2 TROVE domain family, member 2
TUSC2 tumor suppressor candidate 2
UNC93B1 unc-93 homolog B1 (C. elegans)
WAS Wiskott-Aldrich syndrome
WT1 Wilms tumor 1