glomerulosclerosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A glomerulonephritis that is characterized by hardening of the glomerulus in the kidney. (Human Disease Ontology, DOID_0050851)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005264
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Genes

53 gene mutations causing the glomerulosclerosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACTN4 actinin, alpha 4
ADM adrenomedullin
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
BCL2 B-cell CLL/lymphoma 2
CCNI cyclin I
CCR1 chemokine (C-C motif) receptor 1
CD151 CD151 molecule (Raph blood group)
CD1D CD1d molecule
CD2AP CD2-associated protein
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DKC1 dyskeratosis congenita 1, dyskerin
FRAS1 Fraser extracellular matrix complex subunit 1
GAS6 growth arrest-specific 6
GLIS2 GLIS family zinc finger 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLM1 golgi membrane protein 1
GRM1 glutamate receptor, metabotropic 1
HMOX1 heme oxygenase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
INS insulin
ITGA1 integrin, alpha 1
LCAT lecithin-cholesterol acyltransferase
LEP leptin
LEPR leptin receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MPV17 MpV17 mitochondrial inner membrane protein
MTSS1 metastasis suppressor 1
MYH9 myosin, heavy chain 9, non-muscle
MYO1E myosin IE
NFE2L2 nuclear factor, erythroid 2-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
RET ret proto-oncogene
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SCTR secretin receptor
TAL1 T-cell acute lymphocytic leukemia 1
TK1 thymidine kinase 1, soluble
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNS1 tensin 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1