glutathione biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. (Gene Ontology, GO_0006750)
External Link http://amigo.geneontology.org/amigo/term/GO:0006750
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Genes

7 genes participating in the glutathione biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GGT1 gamma-glutamyltransferase 1
HAGH hydroxyacylglutathione hydrolase
MGST2 microsomal glutathione S-transferase 2