glycine encephalopathy Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An amino acid metabolic disorder that involves abnormally high levels of the amino acid glycine in bodily fluids and tissues. (Human Disease Ontology, DOID_9268)
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Genes

47 genes co-occuring with the disease glycine encephalopathy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GLDC glycine dehydrogenase (decarboxylating) 3.40943
GCSH glycine cleavage system protein H (aminomethyl carrier) 2.13971
AMT aminomethyltransferase 1.96239
BOLA3 bolA family member 3 1.7355
NICN1 nicolin 1 1.67277
LIPT2 lipoyl(octanoyl) transferase 2 (putative) 1.64262
GLRX5 glutaredoxin 5 1.4733
LIAS lipoic acid synthetase 1.46144
SUOX sulfite oxidase 1.39608
LIPT1 lipoyltransferase 1 1.29964
GLRB glycine receptor, beta 1.1456
DLD dihydrolipoamide dehydrogenase 1.11561
NFU1 NFU1 iron-sulfur cluster scaffold 1.0627
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.02271
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 1.01174
GLRA1 glycine receptor, alpha 1 0.976323
PNPO pyridoxamine 5'-phosphate oxidase 0.955779
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.931656
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.863456
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.783936
GPHN gephyrin 0.759416
ASL argininosuccinate lyase 0.720461
TALDO1 transaldolase 1 0.691495
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.681894
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.625319
PHGDH phosphoglycerate dehydrogenase 0.608885
PMM2 phosphomannomutase 2 0.606543
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.577327
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.573828
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.552851
ASS1 argininosuccinate synthase 1 0.529994
MUT methylmalonyl CoA mutase 0.390397
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.357814
FABP3 fatty acid binding protein 3, muscle and heart 0.337975
OAT ornithine aminotransferase 0.332487
GC group-specific component (vitamin D binding protein) 0.331025
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.315003
CS citrate synthase 0.309928
LAMA2 laminin, alpha 2 0.30848
MAG myelin associated glycoprotein 0.296211
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.294772
GLUL glutamate-ammonia ligase 0.283655
TH tyrosine hydroxylase 0.279724
HEXA hexosaminidase A (alpha polypeptide) 0.257005
G6PC glucose-6-phosphatase, catalytic subunit 0.238752
MMD monocyte to macrophage differentiation-associated 0.206248
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.205254