Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the glycocholic acid-2454 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
ADCY9 | adenylate cyclase 9 |
AGGF1 | angiogenic factor with G patch and FHA domains 1 |
ANGPTL2 | angiopoietin-like 2 |
ANK1 | ankyrin 1, erythrocytic |
APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
AQP4 | aquaporin 4 |
ARHGAP32 | Rho GTPase activating protein 32 |
ARMCX4 | armadillo repeat containing, X-linked 4 |
BAIAP2 | BAI1-associated protein 2 |
BCAP29 | B-cell receptor-associated protein 29 |
BEGAIN | brain-enriched guanylate kinase-associated |
BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
CCDC85B | coiled-coil domain containing 85B |
CCR2 | chemokine (C-C motif) receptor 2 |
CD59 | CD59 molecule, complement regulatory protein |
CDC14A | cell division cycle 14A |
CDH10 | cadherin 10, type 2 (T2-cadherin) |
CFLAR | CASP8 and FADD-like apoptosis regulator |
COL18A1 | collagen, type XVIII, alpha 1 |
COL4A1 | collagen, type IV, alpha 1 |
CREBZF | CREB/ATF bZIP transcription factor |
CTRL | chymotrypsin-like |
CTSE | cathepsin E |
DEAF1 | DEAF1 transcription factor |
ECE1 | endothelin converting enzyme 1 |
EIF1 | eukaryotic translation initiation factor 1 |
FAM131A | family with sequence similarity 131, member A |
FAM182B | family with sequence similarity 182, member B |
FASLG | Fas ligand (TNF superfamily, member 6) |
FCMR | Fc fragment of IgM receptor |
FGF12 | fibroblast growth factor 12 |
GABARAPL1 | GABA(A) receptor-associated protein like 1 |
GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
HNRNPM | heterogeneous nuclear ribonucleoprotein M |
IGFBP4 | insulin-like growth factor binding protein 4 |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
INCENP | inner centromere protein antigens 135/155kDa |
ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
KDM4B | lysine (K)-specific demethylase 4B |
LAMB3 | laminin, beta 3 |
MAOA | monoamine oxidase A |
MAPK14 | mitogen-activated protein kinase 14 |
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
METTL16 | methyltransferase like 16 |
NEBL | nebulette |
NFYA | nuclear transcription factor Y, alpha |
NOTCH2 | notch 2 |
NPC1 | Niemann-Pick disease, type C1 |
NRF1 | nuclear respiratory factor 1 |
NUP188 | nucleoporin 188kDa |
OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
PARP12 | poly (ADP-ribose) polymerase family, member 12 |
PDE4C | phosphodiesterase 4C, cAMP-specific |
PDIA2 | protein disulfide isomerase family A, member 2 |
PLA2G3 | phospholipase A2, group III |
PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
PNPLA3 | patatin-like phospholipase domain containing 3 |
POU2F2 | POU class 2 homeobox 2 |
PQLC2 | PQ loop repeat containing 2 |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
RNF6 | ring finger protein (C3H2C3 type) 6 |
ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
RPS28 | ribosomal protein S28 |
RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
SAMD4A | sterile alpha motif domain containing 4A |
SFTPC | surfactant protein C |
SIGLEC8 | sialic acid binding Ig-like lectin 8 |
SLC17A2 | solute carrier family 17, member 2 |
SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
SMAD5 | SMAD family member 5 |
SNX13 | sorting nexin 13 |
SOCS1 | suppressor of cytokine signaling 1 |
SPPL2B | signal peptide peptidase like 2B |
ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
STS | steroid sulfatase (microsomal), isozyme S |
SYCP2 | synaptonemal complex protein 2 |
SYT2 | synaptotagmin II |
SYT5 | synaptotagmin V |
TBX5 | T-box 5 |
TEC | tec protein tyrosine kinase |
TEX40 | testis expressed 40 |
TFF2 | trefoil factor 2 |
TMEM140 | transmembrane protein 140 |
TPM3 | tropomyosin 3 |
TRD | T cell receptor delta locus |
TRIM23 | tripartite motif containing 23 |
UCN | urocortin |
VAV2 | vav 2 guanine nucleotide exchange factor |
WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
ZER1 | zyg-11 related, cell cycle regulator |
ZMIZ2 | zinc finger, MIZ-type containing 2 |
ZNF235 | zinc finger protein 235 |
ZNF492 | zinc finger protein 492 |
ZNF507 | zinc finger protein 507 |
ZNF75D | zinc finger protein 75D |
Symbol | Name |
---|---|
ACPP | acid phosphatase, prostate |
ADTRP | androgen-dependent TFPI-regulating protein |
ANXA2P2 | annexin A2 pseudogene 2 |
ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
ATP7B | ATPase, Cu++ transporting, beta polypeptide |
BRAF | B-Raf proto-oncogene, serine/threonine kinase |
BTF3P12 | basic transcription factor 3 pseudogene 12 |
C22ORF46 | chromosome 22 open reading frame 46 |
CA11 | carbonic anhydrase XI |
CBX7 | chromobox homolog 7 |
CD79A | CD79a molecule, immunoglobulin-associated alpha |
CD82 | CD82 molecule |
CDK3 | cyclin-dependent kinase 3 |
CDKL3 | cyclin-dependent kinase-like 3 |
CDR2L | cerebellar degeneration-related protein 2-like |
CENPT | centromere protein T |
CHML | choroideremia-like (Rab escort protein 2) |
CLCF1 | cardiotrophin-like cytokine factor 1 |
COL9A2 | collagen, type IX, alpha 2 |
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
DOK3 | docking protein 3 |
EFNA3 | ephrin-A3 |
EPHA4 | EPH receptor A4 |
EXOSC1 | exosome component 1 |
FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
FGF23 | fibroblast growth factor 23 |
GIPC1 | GIPC PDZ domain containing family, member 1 |
GJA8 | gap junction protein, alpha 8, 50kDa |
HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
HAMP | hepcidin antimicrobial peptide |
HDAC7 | histone deacetylase 7 |
HIST1H2AE | histone cluster 1, H2ae |
HIST1H2AJ | histone cluster 1, H2aj |
HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
HOXA5 | homeobox A5 |
HOXC8 | homeobox C8 |
IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
IGSF6 | immunoglobulin superfamily, member 6 |
IL18 | interleukin 18 |
IL24 | interleukin 24 |
INF2 | inverted formin, FH2 and WH2 domain containing |
KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
KLHL21 | kelch-like family member 21 |
KLHL28 | kelch-like family member 28 |
LIMD2 | LIM domain containing 2 |
LNPEP | leucyl/cystinyl aminopeptidase |
LOC257152 | uncharacterized LOC257152 |
LRP3 | low density lipoprotein receptor-related protein 3 |
LY6D | lymphocyte antigen 6 complex, locus D |
LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
MAPK10 | mitogen-activated protein kinase 10 |
MRAS | muscle RAS oncogene homolog |
MRPL52 | mitochondrial ribosomal protein L52 |
MYBPH | myosin binding protein H |
NCALD | neurocalcin delta |
NCKAP1L | NCK-associated protein 1-like |
NINJ2 | ninjurin 2 |
NIPAL2 | NIPA-like domain containing 2 |
NPFFR1 | neuropeptide FF receptor 1 |
NXPH4 | neurexophilin 4 |
OCEL1 | occludin/ELL domain containing 1 |
OLAH | oleoyl-ACP hydrolase |
OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PADI1 | peptidyl arginine deiminase, type I |
PADI2 | peptidyl arginine deiminase, type II |
PDGFD | platelet derived growth factor D |
PER3 | period circadian clock 3 |
PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
QPCTL | glutaminyl-peptide cyclotransferase-like |
QSER1 | glutamine and serine rich 1 |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RHOB | ras homolog family member B |
SMYD5 | SMYD family member 5 |
SPIN1 | spindlin 1 |
TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
TMEM180 | transmembrane protein 180 |
TMEM209 | transmembrane protein 209 |
TMOD3 | tropomodulin 3 (ubiquitous) |
TRAIP | TRAF interacting protein |
TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
UBTD1 | ubiquitin domain containing 1 |
VEGFC | vascular endothelial growth factor C |
VNN1 | vanin 1 |
YPEL1 | yippee-like 1 (Drosophila) |
ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
ZNF10 | zinc finger protein 10 |
ZNF155 | zinc finger protein 155 |
ZNF493 | zinc finger protein 493 |
ZNF506 | zinc finger protein 506 |
ZNF528 | zinc finger protein 528 |
ZNF552 | zinc finger protein 552 |
ZNF747 | zinc finger protein 747 |