goiter Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency ( HYPOTHYROIDISM), or hormone overproduction ( HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic ( GOITER, ENDEMIC). (Experimental Factor Ontology, EFO_0004283)
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Genes

22 genes co-occuring with the biological term goiter in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CCL5 chemokine (C-C motif) ligand 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DICER1 dicer 1, ribonuclease type III
DIO1 deiodinase, iodothyronine, type I
DIO2 deiodinase, iodothyronine, type II
EDN1 endothelin 1
FAS Fas cell surface death receptor
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FOXP3 forkhead box P3
GPR39 G protein-coupled receptor 39
HMGA1P2 high mobility group AT-hook 1 pseudogene 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IL6 interleukin 6
IYD iodotyrosine deiodinase
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
TEK TEK tyrosine kinase, endothelial
TG thyroglobulin
TPO thyroid peroxidase
TSHR thyroid stimulating hormone receptor
VEGFA vascular endothelial growth factor A