gossypol-3740 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the gossypol-3740 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ACTN3 actinin, alpha 3 (gene/pseudogene)
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPTL4 angiopoietin-like 4
ARC activity-regulated cytoskeleton-associated protein
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARTN artemin
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BBC3 BCL2 binding component 3
BCL6 B-cell CLL/lymphoma 6
BEND5 BEN domain containing 5
BHLHE40 basic helix-loop-helix family, member e40
BHMT2 betaine--homocysteine S-methyltransferase 2
CARS cysteinyl-tRNA synthetase
CBS cystathionine-beta-synthase
CCNG2 cyclin G2
CCNT2 cyclin T2
CCR4 chemokine (C-C motif) receptor 4
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN4 chloride channel, voltage-sensitive 4
CLDN11 claudin 11
CLTCL1 clathrin, heavy chain-like 1
COL7A1 collagen, type VII, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DESI2 desumoylating isopeptidase 2
DMC1 DNA meiotic recombinase 1
DST dystonin
DUSP1 dual specificity phosphatase 1
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EGR4 early growth response 4
ENO2 enolase 2 (gamma, neuronal)
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FAM129A family with sequence similarity 129, member A
GABARAPL1 GABA(A) receptor-associated protein like 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
HMOX1 heme oxygenase 1
IL1RN interleukin 1 receptor antagonist
INSIG2 insulin induced gene 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0040 KIAA0040
KLF4 Kruppel-like factor 4 (gut)
KLHL18 kelch-like family member 18
KREMEN2 kringle containing transmembrane protein 2
LOXL2 lysyl oxidase-like 2
LPIN1 lipin 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MST1 macrophage stimulating 1
MUC13 mucin 13, cell surface associated
NCOA2 nuclear receptor coactivator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRP1 neuropilin 1
NUPR1 nuclear protein, transcriptional regulator, 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORAI2 ORAI calcium release-activated calcium modulator 2
OSMR oncostatin M receptor
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE4D phosphodiesterase 4D, cAMP-specific
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGM5 phosphoglucomutase 5
PLK4 polo-like kinase 4
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLL polymerase (DNA directed), lambda
POU2F2 POU class 2 homeobox 2
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAT1 phosphoserine aminotransferase 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTX3 pentraxin 3, long
PVR poliovirus receptor
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD52 RAD52 homolog (S. cerevisiae)
RARG retinoic acid receptor, gamma
RECQL5 RecQ protein-like 5
RNASE4 ribonuclease, RNase A family, 4
RXRB retinoid X receptor, beta
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQLE squalene epoxidase
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TET3 tet methylcytosine dioxygenase 3
THBD thrombomodulin
TLK1 tousled-like kinase 1
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIB3 tribbles pseudokinase 3
TTC12 tetratricopeptide repeat domain 12
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANKH ANKH inorganic pyrophosphate transport regulator
ARMCX4 armadillo repeat containing, X-linked 4
ASIC3 acid sensing (proton gated) ion channel 3
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BMP4 bone morphogenetic protein 4
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CA11 carbonic anhydrase XI
CBX8 chromobox homolog 8
CD79B CD79b molecule, immunoglobulin-associated beta
CDH19 cadherin 19, type 2
CDON cell adhesion associated, oncogene regulated
CFAP45 cilia and flagella associated protein 45
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CLCN2 chloride channel, voltage-sensitive 2
CORO7 coronin 7
CORT cortistatin
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
CYB5R2 cytochrome b5 reductase 2
CYBRD1 cytochrome b reductase 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DDN dendrin
DMPK dystrophia myotonica-protein kinase
DNAH7 dynein, axonemal, heavy chain 7
DTX2 deltex 2, E3 ubiquitin ligase
EDAR ectodysplasin A receptor
EPHA4 EPH receptor A4
EPN3 epsin 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
FAM189A2 family with sequence similarity 189, member A2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMD1 FERM domain containing 1
GALT galactose-1-phosphate uridylyltransferase
GAN gigaxonin
GBP2 guanylate binding protein 2, interferon-inducible
GLB1L galactosidase, beta 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HOXB5 homeobox B5
HPN hepsin
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KDM8 lysine (K)-specific demethylase 8
KIAA1549L KIAA1549-like
LMTK2 lemur tyrosine kinase 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAK male germ cell-associated kinase
MAP2 microtubule-associated protein 2
MED31 mediator complex subunit 31
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MXD3 MAX dimerization protein 3
NPHP1 nephronophthisis 1 (juvenile)
PAQR5 progestin and adipoQ receptor family member V
PCBP3 poly(rC) binding protein 3
PCDHA9 protocadherin alpha 9
PICK1 protein interacting with PRKCA 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
QSER1 glutamine and serine rich 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPL10L ribosomal protein L10-like
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIX3 SIX homeobox 3
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUSD4 sushi domain containing 4
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TESPA1 thymocyte expressed, positive selection associated 1
TEX15 testis expressed 15
TMEM121 transmembrane protein 121
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRAC T cell receptor alpha constant
TUBA4B tubulin, alpha 4b
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VASH2 vasohibin 2
VGLL3 vestigial-like family member 3
WDR4 WD repeat domain 4
WFDC2 WAP four-disulfide core domain 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF107 zinc finger protein 107
ZNF516 zinc finger protein 516
ZNF702P zinc finger protein 702, pseudogene
ZNF747 zinc finger protein 747