gossypol-6058 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the gossypol-6058 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AMPD3 adenosine monophosphate deaminase 3
ARHGAP26 Rho GTPase activating protein 26
ATF3 activating transcription factor 3
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATXN2L ataxin 2-like
BHLHE40 basic helix-loop-helix family, member e40
BLK BLK proto-oncogene, Src family tyrosine kinase
BTF3P11 basic transcription factor 3 pseudogene 11
C19ORF26 chromosome 19 open reading frame 26
C21ORF2 chromosome 21 open reading frame 2
C8A complement component 8, alpha polypeptide
CABP2 calcium binding protein 2
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CCL23 chemokine (C-C motif) ligand 23
CD70 CD70 molecule
CDHR2 cadherin-related family member 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CRLF2 cytokine receptor-like factor 2
CROCC ciliary rootlet coiled-coil, rootletin
CST4 cystatin S
CTAG2 cancer/testis antigen 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOK4 docking protein 4
DUSP9 dual specificity phosphatase 9
EDA ectodysplasin A
EMID1 EMI domain containing 1
FHL1 four and a half LIM domains 1
FRS3 fibroblast growth factor receptor substrate 3
GAP43 growth associated protein 43
GAS7 growth arrest-specific 7
GLP1R glucagon-like peptide 1 receptor
GPR183 G protein-coupled receptor 183
GRK4 G protein-coupled receptor kinase 4
GRM4 glutamate receptor, metabotropic 4
GRM8 glutamate receptor, metabotropic 8
HCG4B HLA complex group 4B (non-protein coding)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
INHBE inhibin, beta E
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JPH3 junctophilin 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIF1C kinesin family member 1C
KIF21B kinesin family member 21B
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MEF2D myocyte enhancer factor 2D
MIR622 microRNA 622
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NDRG1 N-myc downstream regulated 1
NRL neural retina leucine zipper
NUPR1 nuclear protein, transcriptional regulator, 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PAX8 paired box 8
PCDHB17P protocadherin beta 17 pseudogene
PDLIM5 PDZ and LIM domain 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRB1 proline-rich protein BstNI subfamily 1
PRDM9 PR domain containing 9
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB3B RAB3B, member RAS oncogene family
RAG2 recombination activating gene 2
RNF126P1 ring finger protein 126 pseudogene 1
SAA3P serum amyloid A3 pseudogene
SAMD9 sterile alpha motif domain containing 9
SARM1 sterile alpha and TIR motif containing 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRPK3 SRSF protein kinase 3
SSX1 synovial sarcoma, X breakpoint 1
STS steroid sulfatase (microsomal), isozyme S
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TPMT thiopurine S-methyltransferase
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPM1 transient receptor potential cation channel, subfamily M, member 1
ULBP1 UL16 binding protein 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WNT8B wingless-type MMTV integration site family, member 8B
ZNF44 zinc finger protein 44
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD17B abhydrolase domain containing 17B
ADCY7 adenylate cyclase 7
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARRB1 arrestin, beta 1
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
B3GNT1
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
C1ORF115 chromosome 1 open reading frame 115
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CBR3 carbonyl reductase 3
CCNJ cyclin J
CDCA8 cell division cycle associated 8
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLEC16A C-type lectin domain family 16, member A
COPZ2 coatomer protein complex, subunit zeta 2
CRY2 cryptochrome circadian clock 2
DGAT1 diacylglycerol O-acyltransferase 1
DNA2 DNA replication helicase/nuclease 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F8 E2F transcription factor 8
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
ERCC6L excision repair cross-complementation group 6-like
F2R coagulation factor II (thrombin) receptor
FAM204A family with sequence similarity 204, member A
FBXO3 F-box protein 3
FHOD1 formin homology 2 domain containing 1
GLI3 GLI family zinc finger 3
HSPA2 heat shock 70kDa protein 2
IL17RB interleukin 17 receptor B
IQCG IQ motif containing G
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIFC1 kinesin family member C1
KLHL21 kelch-like family member 21
KLHL26 kelch-like family member 26
LOXL1 lysyl oxidase-like 1
MMP3 matrix metallopeptidase 3
MSX1 msh homeobox 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NEK11 NIMA-related kinase 11
NES nestin
NOL12 nucleolar protein 12
NPY1R neuropeptide Y receptor Y1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDHB8 protocadherin beta 8
PCNXL4 pecanex-like 4 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMP22 peripheral myelin protein 22
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PORCN porcupine homolog (Drosophila)
RAB30 RAB30, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBL1 retinoblastoma-like 1
REEP1 receptor accessory protein 1
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPIA ribose 5-phosphate isomerase A
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SP1 Sp1 transcription factor
SPC25 SPC25, NDC80 kinetochore complex component
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYCP2 synaptonemal complex protein 2
TESC tescalcin
TMEM180 transmembrane protein 180
TMEM2 transmembrane protein 2
TPST2 tyrosylprotein sulfotransferase 2
TRIM5 tripartite motif containing 5
TSPYL2 TSPY-like 2
TTF2 transcription termination factor, RNA polymerase II
VWA1 von Willebrand factor A domain containing 1
WDR37 WD repeat domain 37
WLS wntless Wnt ligand secretion mediator
ZBED1 zinc finger, BED-type containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF227 zinc finger protein 227
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573
ZNF767P zinc finger family member 767, pseudogene
ZNF83 zinc finger protein 83