gout Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi. (Experimental Factor Ontology, EFO_0004274)
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Genes

32 genes associated with the disease gout in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGBL4 ATP/GTP binding protein-like 4
APOA1 apolipoprotein A-I
APOE apolipoprotein E
ASIC2 acid sensing (proton gated) ion channel 2
CNTLN centlein, centrosomal protein
COMT catechol-O-methyltransferase
GCKR glucokinase (hexokinase 4) regulator
GRIK2 glutamate receptor, ionotropic, kainate 2
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL4 interleukin 4
IL6 interleukin 6
LRRC16A leucine rich repeat containing 16A
MAOA monoamine oxidase A
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
PDZK1 PDZ domain containing 1
PRKG2 protein kinase, cGMP-dependent, type II
PYGM phosphorylase, glycogen, muscle
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RELN reelin
SF1 splicing factor 1
SLC16A9 solute carrier family 16, member 9
SLC17A1 solute carrier family 17 (organic anion transporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
TLL1 tolloid-like 1
TNF tumor necrosis factor